T67933 |
BAY-4931
|
423150-91-8
|
99.47%
|
|
BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.
|
T6917 |
Oleuropein
|
32619-42-4
|
99.46%
|
|
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
|
T23389 |
SR1664
|
1338259-05-4
|
99.43%
|
|
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphoryl...
|
T14176 |
Aleglitazar
|
475479-34-6
|
99.42%
|
|
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for ...
|
T67936 |
BAY-0069
|
420826-65-9
|
99.41%
|
|
BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be u...
|
T12527L |
Mavodelpar free acid hydrochloride
|
|
99.39%
|
|
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.
|
T9767 |
CC618
|
1680204-90-3
|
99.37%
|
|
CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.
|
T19500 |
Palmitelaidic Acid
|
10030-73-6
|
99.36%
|
|
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
|
T3170 |
Troglitazone
|
97322-87-7
|
99.36%
|
|
Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.
|
T6689 |
T0070907
|
313516-66-4
|
99.36%
|
|
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
|
T3954 |
Adelmidrol
|
1675-66-7
|
99.35%
|
|
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
|
T28501 |
Ragaglitazar
|
222834-30-2
|
99.33%
|
|
Ragaglitazar(NNC-61-0029) is a potent dual PPARα and PPARγ agonist that has shown potent lipid-lowering and insulin sensitizing effects in animal models.Ragaglit...
|
T1622 |
Rosiglitazone maleate
|
155141-29-0
|
99.33%
|
|
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplas...
|
T25741 |
Linotroban
|
120824-08-0
|
99.31%
|
|
Linotroban(CL-871502) is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.
|
T21587 |
Muraglitazar
|
331741-94-7
|
99.31%
|
|
Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitr...
|
T7395 |
Lanifibranor
|
927961-18-0
|
99.3%
|
|
Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα...
|
T68022 |
Sulotroban
|
72131-33-0
|
99.29%
|
|
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
|
TN1525 |
Convallatoxin
|
508-75-8
|
99.27%
|
|
Convallatoxin is a natural product
|
T13289 |
EHP-101
|
1818428-24-8
|
99.22%
|
|
EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents die...
|
T31213 |
Dazmegrel
|
76894-77-4
|
99.20%
|
|
Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal preg...
|