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PPAR

In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis of higher organisms.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T67933 BAY-4931 423150-91-8 99.47%
BAY-4931
BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.
T6917 Oleuropein 32619-42-4 99.46%
Oleuropein
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
T23389 SR1664 1338259-05-4 99.43%
SR1664
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphoryl...
T14176 Aleglitazar 475479-34-6 99.42%
Aleglitazar
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for ...
T67936 BAY-0069 420826-65-9 99.41%
BAY-0069
BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be u...
T12527L Mavodelpar free acid hydrochloride 99.39%
Mavodelpar free acid hydrochloride
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.
T9767 CC618 1680204-90-3 99.37%
CC618
CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.
T19500 Palmitelaidic Acid 10030-73-6 99.36%
Palmitelaidic Acid
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
T3170 Troglitazone 97322-87-7 99.36%
Troglitazone
Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.
T6689 T0070907 313516-66-4 99.36%
T0070907
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
T3954 Adelmidrol 1675-66-7 99.35%
Adelmidrol
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
T28501 Ragaglitazar 222834-30-2 99.33%
Ragaglitazar
Ragaglitazar(NNC-61-0029) is a potent dual PPARα and PPARγ agonist that has shown potent lipid-lowering and insulin sensitizing effects in animal models.Ragaglit...
T1622 Rosiglitazone maleate 155141-29-0 99.33%
Rosiglitazone maleate
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplas...
T25741 Linotroban 120824-08-0 99.31%
Linotroban
Linotroban(CL-871502) is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.
T21587 Muraglitazar 331741-94-7 99.31%
Muraglitazar
Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitr...
T7395 Lanifibranor 927961-18-0 99.3%
Lanifibranor
Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα...
T68022 Sulotroban 72131-33-0 99.29%
Sulotroban
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
TN1525 Convallatoxin 508-75-8 99.27%
Convallatoxin
Convallatoxin is a natural product
T13289 EHP-101 1818428-24-8 99.22%
EHP-101
EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents die...
T31213 Dazmegrel 76894-77-4 99.20%
Dazmegrel
Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal preg...
BAY-4931
T67933
BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.
Oleuropein
T6917
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
SR1664
T23389
SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphoryl...
Aleglitazar
T14176
Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for ...
BAY-0069
T67936
BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be u...
Mavodelpar free acid hydrochloride
T12527L
Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.
CC618
T9767
CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.
Palmitelaidic Acid
T19500
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
Troglitazone
T3170
Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.
T0070907
T6689
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
Adelmidrol
T3954
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
Ragaglitazar
T28501
Ragaglitazar(NNC-61-0029) is a potent dual PPARα and PPARγ agonist that has shown potent lipid-lowering and insulin sensitizing effects in animal models.Ragaglit...
Rosiglitazone maleate
T1622
Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplas...
Linotroban
T25741
Linotroban(CL-871502) is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.
Muraglitazar
T21587
Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitr...
Lanifibranor
T7395
Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα...
Sulotroban
T68022
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
Convallatoxin
TN1525
Convallatoxin is a natural product
EHP-101
T13289
EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents die...
Dazmegrel
T31213
Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal preg...
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TargetMol