T3S0012 |
Coniferyl ferulate
|
63644-62-2
|
98%
|
|
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental...
|
T17216 |
Valspodar
|
121584-18-7
|
98%
|
|
Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.
|
T16026 |
MCI826
|
140646-80-6
|
98%
|
|
MCI826 is a potent and selective antagonist of P-glycoprotein (P-gp) and peptide leukotrienes (p-LTs), showing anti-asthmatic activity in a guinea pig model of a...
|
T60009 |
YS-370
|
2470908-79-1
|
98%
|
|
YS-370 is an orally active inhibitor of P-gp and shows moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance to paclitaxel and col...
|
TN1651 |
Furanodiene
|
19912-61-9
|
98%
|
|
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
|
TN1425 |
Bacoside A3
|
157408-08-7
|
98%
|
|
Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
|
T12341 |
P-gp inhibitor 1
|
2050747-49-2
|
98%
|
|
P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).
|
T2S1200 |
Sinapine
|
18696-26-9
|
98%
|
|
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant an...
|
T77575 |
P-gb-IN-1
|
2632874-49-6
|
98%
|
|
P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydr...
|
T12540 |
Pristinamycin IA
|
3131-03-1
|
98%
|
|
Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.
|
T2S1120 |
Ganoderenic acid B
|
100665-41-6
|
98%
|
|
Ganoderenic acid B, a natural product derived from Ganoderma lucidum, can work by inhibiting the transport function of ABCB1 and enhancing the cytotoxicity of ch...
|
T4059 |
Selamectin
|
220119-17-5
|
98%
|
|
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in ...
|
T9601 |
Tepotinib hydrochloride(1 : x)
|
1103508-80-0
|
98%
|
|
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14 s...
|