T12770 |
RR-11a analog
|
685543-66-2
|
98.64%
|
|
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vagin...
|
T10339 |
Antitrypanosomal agent 1
|
75144-12-6
|
98.6%
|
|
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase...
|
T16326 |
Cipargamin
|
1193314-23-6
|
98.58%
|
|
Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum.
|
T23132 |
Pentamidine dihydrochloride
|
50357-45-4
|
98.58%
|
|
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Trypa...
|
T3202 |
Fluensulfone
|
318290-98-1
|
98.57%
|
|
Fluensulfone (MCW-2) is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target...
|
T10423 |
AWZ1066S
|
2239272-16-1
|
98.54%
|
|
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).
|
T77684 |
4-(2-Aminoethyl)amino-7-chloroquinoline
|
5407-57-8
|
98.53%
|
|
4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study of malaria...
|
T15277 |
Fervenulin
|
483-57-8
|
98.51%
|
|
Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 with nematicidal activity. It also inhibits egg hatch and J2 mortality of M. in...
|
T3524 |
Halofuginone hydrobromide
|
64924-67-0
|
98.5%
|
|
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
|
T23411L |
T-0156
|
324572-92-1
|
98.42%
|
|
T-0156 is a novel, potent and selective phosphodiesterase type 5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinit...
|
T8193 |
α-Thujone
|
546-80-5
|
98.41%
|
|
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
|
T10835L1 |
Cletoquine hydrochloride
|
159358-29-9
|
98.4%
|
|
Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to aga...
|
T0969 |
Doramectin
|
117704-25-3
|
98.4%
|
|
Doramectin (Dectomax) is an antiparasitic agent.
|
T38724 |
Modoflaner
|
1331922-53-2
|
98.4%
|
|
Modoflaner is an antiparasitic (veterinary use).
|
T5S2358 |
Dehydrocorydaline
|
30045-16-0
|
98.36%
|
|
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stim...
|
T0836 |
Sulfadoxine
|
2447-57-6
|
98.36%
|
|
Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial propert...
|
T0838 |
Triclabendazole
|
68786-66-3
|
98.35%
|
|
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
|
T1383 |
Bitoscanate
|
4044-65-9
|
98.32%
|
|
Bitoscanate (PDITC) is used in the treatment of hookworms.
|
TN3033 |
4'-Hydroxy-2,4-dimethoxychalcone
|
151135-64-7
|
98.31%
|
|
4'-Hydroxy-2,4-dimethoxychalcone is a naturally occurring chalcone derivative from the herbal resin of the red geranium Dragon's Blood.4'-Hydroxy-2,4-dimethoxych...
|
T16125 |
MMV390048
|
1314883-11-8
|
98.28%
|
|
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP bindin...
|