T38001 |
LEI-401
|
2393840-15-6
|
99.79%
|
|
LEI-401 is a selective and potent NAPE-PLD inhibitor that crosses the blood-brain barrier (IC50: 27 nM).LEI-401 reduces the level of n-acylethanolamines (NAEs) i...
|
T14829 |
Bromoenol lactone
|
88070-98-8
|
98%
|
|
Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2β; IC50: ~7 μM). It inhibits antigen...
|
T11873 |
Lp-PLA2-IN-2
|
2071636-15-0
|
98%
|
|
Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.
|
T78141 |
LFHP-1c
|
2102347-47-5
|
98%
|
|
LFHP-1c, a neuroprotective PGAM5 inhibitor, demonstrates efficacy in preserving blood-brain barrier integrity following ischemic stroke. It achieves this by bind...
|
T78161 |
VU0364739
|
1244639-78-8
|
98%
|
|
VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].
|
T79010 |
Lp-PLA2-IN-12
|
2637485-14-2
|
98%
|
|
Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-relate...
|
T79073 |
Lp-PLA2-IN-13
|
2756855-62-4
|
98%
|
|
Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].
|
T79074 |
Lp-PLA2-IN-14
|
2756855-66-8
|
98%
|
|
Lp-PLA2-IN-14 (Compound 19), an inhibitor of rhLp-PLA2, exhibits a potent inhibitory effect with a pIC50 value of 8.4. This compound is applicable in research pe...
|
T79075 |
Lp-PLA2-IN-15
|
1865796-11-7
|
98%
|
|
Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].
|
T79076 |
Lp-PLA2-IN-16
|
1865780-73-9
|
98%
|
|
Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].
|
T79321 |
NSMase2-IN-1
|
|
98%
|
|
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM. It demonstrates metabolic stabilit...
|
T82421 |
FAAH/cPLA2α-IN-1
|
1696401-38-3
|
98%
|
|
FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (IC50...
|
T83225 |
A4333
|
|
98%
|
|
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2. It is noted for its significant role in antitumor act...
|
T83226 |
A3373
|
|
98%
|
|
A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of 325...
|
T11835 |
LCL521
|
1226851-11-1
|
98%
|
|
LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor.
|
TN3139 |
5α-Hydroxycostic acid
|
132185-83-2
|
98%
|
|
5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.
|
T74778 |
ASM-IN-1
|
2913151-46-7
|
98%
|
|
ASM-IN-1 is a potent, orally active inhibitor of acid sphingomyelinase (ASM) with an IC50 of 1.5 µM, demonstrating antiatherosclerotic and anti-inflammatory acti...
|
T9001 |
Desketoraloxifene
|
216570-81-9
|
98%
|
|
Desketoraloxifene is a selective estrogen receptor modulator, inhibiting mammalian PLD (PLD1 and PLD2).
|
T15948 |
MAFP
|
188404-10-6
|
98%
|
|
MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase. MAFP is an active-site directed and irreversible inhibi...
|
TN4247 |
Ikshusterol 3-O-glucoside
|
112137-81-2
|
98%
|
|
Ikshusterol 3-O-glucoside has a potent snake-venom neutralizing capacity and it might be a potential molecule for the therapeutic treatment for snakebites.
|