Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat No.	product name
T0038	Doxapram hydrochloride monohydrate	Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
T0075	Nicorandil	Nicorandil(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. First...
T0126	Diazoxide	Diazoxide is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it l...
T0127	Glimepiride	Glimepiride is a long-acting, third-generation sulfonylurea with hypoglycemic activity.
T0150	Hydroxyhexamide	Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.
T0150	Hydroxyhexamide	Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.
T0161	Pantoprazole Sodium Hydrate	Pantoprazole is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease...
T0266	Quinidine hydrochloride	Quinidine is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and dec...
T0342	Carvedilol phosphate	Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
T0344	Miconazole	Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion.
T0365	Thioridazine hydrochloride	Thioridazine, an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
T0371	Gliquidone	Gliquidone is a potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater bindin...
T0386	Ropivacaine hydrochloride	Ropivacaine hydrochloride is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity.
T0447	Carvedilol	Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intr...
T0451	Minoxidil	Minoxidil is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
T0483	Sotalol hydrochloride	Sotalol Hydrochloride is the hydrochloride salt form of sotalol, an ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties.
T0690	Quinine	Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cra...
T0700	Ursodeoxycholic acid	Ursodeoxycholic acid can be used to dissolve gallstones and reduce cholesterol absorption.
T0791	Reserpine	Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resu...
T0816	Acetohexamide	Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwa...
T0847	Chenodeoxycholic acid	Chenodiol is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorb...
T0866	Propafenone	Propafenone is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythm...
T0916	Butyl 4-aminobenzoate	Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
T0954	Anestan	Halothane is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be ade...
T0974	Novobiocin Sodium	Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces nive...
T1050	Prazosin hydrochloride	Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not complet...
T1054	Tolbutamide	Tolbutamide is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
T1073	Dronedarone hydrochloride	Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
T1088	Repaglinide	Repaglinide is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been...
T10979	DCPIB	DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μ...
T1138	Taurocholic acid sodium salt hydrate	Taurocholic acid sodium salt hydrate is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredient of the bile of carnivorous ...
T1146	Nifedipine	Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and v...
T11753	Keto Ziprasidone	Ziprasidone, an antipsychotic agent, is a combined 5-HT (serotonin) and dopamine receptor antagonist. Keto Ziprasidone is an impurity of Ziprasidone.
T1204	Bendroflumethiazide	A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, ede...
T1206	Amsacrine	Amsacrine (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. Amsacrine also expresses topoisomerase inhibitor activity, specific...
T12478	Pinacidil monohydrate	Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.
T12504	(+)-KCC2 blocker 1	(+)-KCC2 blocker 1 is a selective blocker of K+-Cl- cotransporter KCC2(IC50 of 0.4 μM).
T1260	Sodium cromoglycate	Cromolyn sodium is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
T1266	Terfenadine	Terfenadine is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistami...
T1278	Astemizole	Astemizole is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors...