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Search Result

Search Results for " potassium-channel "

Targets

Potassium Channel

261

Compounds

31

Natural Products

11

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T10674 Potassium Channel Activator 1 ZINC34634569 Potassium Channel
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.
T20968 CyPPA Potassium Channel , Dopamine Receptor
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization.
T10977 DCEBIO Potassium Channel
DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84...
T27624 Iptakalim Hydrochloride Potassium Channel , AChR
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2...
T15385 Glibornuride Potassium Channel
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.
T13164 Tipepidine hydrochloride Potassium Channel , Dopamine Receptor
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
T2604 1-EBIO Calcium Channel
1-EBIO (1-EBIO) is a calium channel agonist.
T14982 Clofilium tosylate Potassium Channel
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.
T9714 Atpenin A5 Potassium Channel
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].
T10979 DCPIB Potassium Channel , Chloride channel
DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1...
T4294 NS 11021 NS11021 Potassium Channel
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels
T0386L Ropivacaine LEA-103 HCl Potassium Channel , Sodium Channel
Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.
T0386 Ropivacaine hydrochloride Ropivacaine monohydrochloride Potassium Channel , Sodium Channel
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity.
T10566 BMS-191095 Potassium Channel
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
T13320L VU591 Potassium Channel
1222810-74-3
T7653 JNJ 303 Potassium Channel
JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
T4224 ML335 Potassium Channel
ML335 is a selective activator of TREK-1 and TREK-2.
T3102 NS-1619 Apoptosis , Potassium Channel
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T3959 ICA-069673 ICA069673 Potassium Channel
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
T16347 NS3623 Potassium Channel
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic e...
T7612 ICA 110381 Potassium Channel
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
T16110 ML418 Potassium Channel
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
T3192 NS1643 Potassium Channel , HER , Autophagy
NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.
T1752 NS6180 Potassium Channel
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
T22745 DPO-1 Potassium Channel
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
T12255 NS19504 Potassium Channel
NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM. NS19504 shows relaxing effect on bladder smooth muscle spontaneous phasic contractions[1].
T60061 RU-TRAAK-2 Potassium Channel
RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.
T8581 Flecainide hydrochloride Others
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.
T5444 CLP290 CLP-290 Potassium Channel
CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatric indications.
T6245 BAPTA-AM BAPTA/AM Potassium Channel
BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM). BAPTA-AM has a 105-fold higher affinity for Ca2+ than for Mg2+, and can be used for...
T4316 ML365 Potassium Channel
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
T13320 VU591 hydrochloride Potassium Channel
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50：0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr...
T2712 Nifekalant hydrochloride Potassium Channel
Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.
T7538 Tetraethylammonium chloride Potassium Channel
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties.
T7899 VU0810464 Potassium Channel
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
T9778 KCNQ1 activator-1  Potassium Channel
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- is a potent KCNQ1 channel activator that can be used in long QT syndrome (LQTS) studies.
T16420 P-1075 Potassium Channel
P-1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species causing cardioprotection of rabbit hearts. P-1075 is an effective activator of sulfonylurea receptor 2-associated ATP-sensitive potassium c...
T0916 Butamben Butyl 4-aminobenzoate Potassium Channel , Calcium Channel , Sodium Channel
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
T15545 ICA-27243 Potassium Channel
ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-27243 also has antiepileptic and anticonvulsant effects.
T1449 Hydrochlorothiazide HCTZ Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
T7506 Yoda 1 Piezo Channel
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
T0030 Bupivacaine hydrochloride Vivacaine,Bupivacaine HCl Sodium Channel
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol...
T0858 Flufenamic acid Arlef,Nichisedan,Achless Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T0451 Minoxidil U10858 Potassium Channel , COX
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
T9070 ASP2905 ASP-2905 Potassium Channel
ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities
T9522 Rimtuzalcap CAD-1883 Potassium Channel
Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), is employed in the study of movement disorders such as spin...
T6186 TRAM-34 Triarylmethane-34,TRAM 34 Potassium Channel , IκB/IKK
TRAM-34 (Triarylmethane-34) (Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34(TRA...
T3528 Senicapoc ICA-17043 Potassium Channel
Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 =...
T0979 Dequalinium chloride Dequafungan,Danical,Decabis Potassium Channel , PKC
Dequalinium chloride (Decabis) , a topical bacteriostat, is a selective blocker of apamin-sensitive K+ channels. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ...
T1054 Tolbutamide HLS 831 Potassium Channel , Autophagy
Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.

Compounds

Potassium Channel Activator 1
T10674
Synonym: ZINC34634569
Target: Potassium Channel
CyPPA
T20968
Synonym:
Target: Potassium Channel, Dopamine Receptor
DCEBIO
T10977
Synonym:
Target: Potassium Channel
Iptakalim Hydrochloride
T27624
Synonym:
Target: Potassium Channel, AChR
Glibornuride
T15385
Synonym:
Target: Potassium Channel
Tipepidine hydrochloride
T13164
Synonym:
Target: Potassium Channel, Dopamine Receptor
1-EBIO
T2604
Synonym:
Target: Calcium Channel
Clofilium tosylate
T14982
Synonym:
Target: Potassium Channel
Atpenin A5
T9714
Synonym:
Target: Potassium Channel
DCPIB
T10979
Synonym:
Target: Potassium Channel, Chloride channel
NS 11021
T4294
Synonym: NS11021
Target: Potassium Channel
Ropivacaine
T0386L
Synonym: LEA-103 HCl
Target: Potassium Channel, Sodium Channel
Ropivacaine hydrochloride
T0386
Synonym: Ropivacaine monohydrochloride
Target: Potassium Channel, Sodium Channel
BMS-191095
T10566
Synonym:
Target: Potassium Channel
VU591
T13320L
Synonym:
Target: Potassium Channel
JNJ 303
T7653
Synonym:
Target: Potassium Channel
ML335
T4224
Synonym:
Target: Potassium Channel
NS-1619
T3102
Synonym:
Target: Apoptosis, Potassium Channel
ICA-069673
T3959
Synonym: ICA069673
Target: Potassium Channel
NS3623
T16347
Synonym:
Target: Potassium Channel
ICA 110381
T7612
Synonym:
Target: Potassium Channel
ML418
T16110
Synonym:
Target: Potassium Channel
NS1643
T3192
Synonym:
Target: Potassium Channel, HER, Autophagy
NS6180
T1752
Synonym:
Target: Potassium Channel
DPO-1
T22745
Synonym:
Target: Potassium Channel
NS19504
T12255
Synonym:
Target: Potassium Channel
RU-TRAAK-2
T60061
Synonym:
Target: Potassium Channel
Flecainide hydrochloride
T8581
Synonym:
Target: Others
CLP290
T5444
Synonym: CLP-290
Target: Potassium Channel
BAPTA-AM
T6245
Synonym: BAPTA/AM
Target: Potassium Channel
ML365
T4316
Synonym:
Target: Potassium Channel
VU591 hydrochloride
T13320
Synonym:
Target: Potassium Channel
Nifekalant hydrochloride
T2712
Synonym:
Target: Potassium Channel
Tetraethylammonium chloride
T7538
Synonym:
Target: Potassium Channel
VU0810464
T7899
Synonym:
Target: Potassium Channel
KCNQ1 activator-1 
T9778
Synonym:
Target: Potassium Channel
P-1075
T16420
Synonym:
Target: Potassium Channel
Butamben
T0916
Synonym: Butyl 4-aminobenzoate
Target: Potassium Channel, Calcium Channel, Sodium Channel
ICA-27243
T15545
Synonym:
Target: Potassium Channel
Hydrochlorothiazide
T1449
Synonym: HCTZ
Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad
Yoda 1
T7506
Synonym:
Target: Piezo Channel
Bupivacaine hydrochloride
T0030
Synonym: Vivacaine,Bupivacaine HCl
Target: Sodium Channel
Flufenamic acid
T0858
Synonym: Arlef,Nichisedan,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
Minoxidil
T0451
Synonym: U10858
Target: Potassium Channel, COX
ASP2905
T9070
Synonym: ASP-2905
Target: Potassium Channel
Rimtuzalcap
T9522
Synonym: CAD-1883
Target: Potassium Channel
TRAM-34
T6186
Synonym: Triarylmethane-34,TRAM 34
Target: Potassium Channel, IκB/IKK
Senicapoc
T3528
Synonym: ICA-17043
Target: Potassium Channel
Dequalinium chloride
T0979
Synonym: Dequafungan,Danical,Decabis
Target: Potassium Channel, PKC
Tolbutamide
T1054
Synonym: HLS 831
Target: Potassium Channel, Autophagy
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T0690 Quinine Potassium Channel , Platelet aggregation , Parasite
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances...
T37709 2,2,2-Trichloroethanol Potassium Channel , Endogenous Metabolite
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...
T8189 Dihydroberberine Potassium Channel , HSP , HER
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...
TN1092 O-Nornuciferine Potassium Channel , HER
O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
T0801 Tannic acid Gallotannic acid Potassium Channel , HER , CXCR
Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
T3S1873 Talatisamine Potassium Channel
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...
T3054 Daurisoline (R,R)-Daurisoline Others , Potassium Channel , Autophagy
Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.
T1186 Ifenprodil Tartrate Potassium Channel , NMDAR , iGluR
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T3A2467 Allocryptopine Thalictrimine,Fagarine I Potassium Channel
Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
T4333 Quinine dihydrochloride Quinine bimuriate Others
Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).
TMS2171 (±)-Naringenin Salipurpol,Naringenine,Naringenin Potassium Channel
(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
T7938 Quinidine Parasite
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.
T7210 Guanosine 5'-diphosphate GDP Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T8182 Guanfu base A Guan-fu base A P450 , Potassium Channel , HER
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
T3S0081 Oxypeucedanin (+-)-Oxypeucedanin,Oxypeucadanin Potassium Channel
1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...
T3876 Loureirin B PAI-1 , ERK , Potassium Channel , JNK
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...
T3S0870 Paederosidic acid methyl ester ATPase , Potassium Channel , NO Synthase
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
T3092 Nigericin sodium salt Potassium Channel , NOD-like Receptor (NLR) , Antibacterial , Antibiotic , NOD
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-...
T0266 Quinidine hydrochloride monohydrate Quinidine hydrochloride Potassium Channel , Sodium Channel , Parasite
Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and decreases automaticity. This alkaloid...
T7056 Dronedarone SR 33589 P450 , Potassium Channel , Calcium Channel , Sodium Channel , Adrenergic Receptor , AChR , Autophagy
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
T2996 Tetrandrine NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A Potassium Channel , Calcium Channel
Tetrandrine (Sinomenine A) is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade of the G1 phase of the c...
T6631 Quinine hydrochloride dihydrate Quinine HCl Dihydrate Potassium Channel , Parasite
Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.
T8040 Cholesterol myristate Cholesteryl myristate,Cholesteryl tetradecanoate Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the i...
T3402 20(S)-Ginsenoside Rg3 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3 EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
T8125 Quinidine sulfate dihydrate Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate P450
Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor
TN4883 Quinine sulfate dihydrate Others
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...
T3604 Sodium dichloroacetate Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA) Apoptosis , Dehydrogenase , Reactive Oxygen Species , PDK
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion chann...
T3929 Kaurenoic acid Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid Others
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...
T75333 Quinine hemisulfate hydrate
Quinine hemisulfate hydrate, an alkaloid extracted from the cinchona tree bark, serves as an anti-malarial agent and potassium channel inhibitor. It specifically targets and inhibits WT mouse Slo3 (K Ca 5.1) channel curr...
TN3636 Chlorahololide C Potassium Channel
Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with the IC(50) value of 3.6 +/- 10.1 mu M.
T27564 Hymenidin 5-HT Receptor
Hymenidin, an alkaloid isolated from the Okinawan sponge Hymeniacidon sp. is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor with potential antiprotozoal effects.It selectively...

Natural Products

Quinine
T0690
Synonym:
Target: Potassium Channel, Platelet aggregation, Parasite
2,2,2-Trichloroethanol
T37709
Synonym:
Target: Potassium Channel, Endogenous Metabolite
Dihydroberberine
T8189
Synonym:
Target: Potassium Channel, HSP, HER
O-Nornuciferine
TN1092
Synonym:
Target: Potassium Channel, HER
Tannic acid
T0801
Synonym: Gallotannic acid
Target: Potassium Channel, HER, CXCR
Talatisamine
T3S1873
Synonym:
Target: Potassium Channel
Daurisoline
T3054
Synonym: (R,R)-Daurisoline
Target: Others, Potassium Channel, Autophagy
Ifenprodil Tartrate
T1186
Synonym:
Target: Potassium Channel, NMDAR, iGluR
Allocryptopine
T3A2467
Synonym: Thalictrimine,Fagarine I
Target: Potassium Channel
Quinine dihydrochloride
T4333
Synonym: Quinine bimuriate
Target: Others
(±)-Naringenin
TMS2171
Synonym: Salipurpol,Naringenine,Naringenin
Target: Potassium Channel
Quinidine
T7938
Synonym:
Target: Parasite
Guanosine 5'-diphosphate
T7210
Synonym: GDP
Target: Endogenous Metabolite
Guanfu base A
T8182
Synonym: Guan-fu base A
Target: P450, Potassium Channel, HER
Oxypeucedanin
T3S0081
Synonym: (+-)-Oxypeucedanin,Oxypeucadanin
Target: Potassium Channel
Loureirin B
T3876
Synonym:
Target: PAI-1, ERK, Potassium Channel, JNK
Paederosidic acid methyl ester
T3S0870
Synonym:
Target: ATPase, Potassium Channel, NO Synthase
Nigericin sodium salt
T3092
Synonym:
Target: Potassium Channel, NOD-like Receptor (NLR), Antibacterial, Antibiotic, NOD
Quinidine hydrochloride monohydrate
T0266
Synonym: Quinidine hydrochloride
Target: Potassium Channel, Sodium Channel, Parasite
Dronedarone
T7056
Synonym: SR 33589
Target: P450, Potassium Channel, Calcium Channel, Sodium Channel, Adrenergic Receptor, AChR, Autophagy
Tetrandrine
T2996
Synonym: NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A
Target: Potassium Channel, Calcium Channel
Quinine hydrochloride dihydrate
T6631
Synonym: Quinine HCl Dihydrate
Target: Potassium Channel, Parasite
Cholesterol myristate
T8040
Synonym: Cholesteryl myristate,Cholesteryl tetradecanoate
Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR
20(S)-Ginsenoside Rg3
T3402
Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Quinidine sulfate dihydrate
T8125
Synonym: Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate
Target: P450
Quinine sulfate dihydrate
TN4883
Synonym:
Target: Others
Sodium dichloroacetate
T3604
Synonym: Sodium Dichloroacetate,DCA,BCA,bichloroacetic acid,Sodium dichloroacetate (DCA)
Target: Apoptosis, Dehydrogenase, Reactive Oxygen Species, PDK
Kaurenoic acid
T3929
Synonym: Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid
Target: Others
Quinine hemisulfate hydrate
T75333
Synonym:
Target:
Chlorahololide C
TN3636
Synonym:
Target: Potassium Channel
Hymenidin
T27564
Synonym:
Target: 5-HT Receptor

Recombinant Proteins

Species：
Human (9)
Heteroscodra maculata (1)
Rat (1)
Expression System：
E. coli (8)
in vitro E. coli expression system (3)
Tag：
N-terminal 10xHis-tagged (2)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (2)
N-terminal 6xHis-tagged (2)
His (1)
N-6His (1)
N-terminal 6xHis-SUMO-tagged (1)
N-terminal 6xHis-SUMO-tagged and C-terminal Myc-tagged (1)
Tag-Free (1)
Cat No. Product Name Species Expression System
TMPH-01889 KCNK3 Protein, Human, Recombinant (His & Myc) Human in vitro E. coli expression system
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassi...
TMPH-01891 KCNE2 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled wit...
TMPH-02309 KCNAB2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expressi...
TMPH-01890 KCNA1 Protein, Human, Recombinant (His) Human E. coli
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney. Contributes to the regulation of the ...
TMPY-03615 CSEN Protein, Human, Recombinant (His) Human E. coli
KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to th...
TMPH-01609 LGI1 Protein, Human, Recombinant (His & Myc) Human E. coli
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regula...
TMPJ-00652 PSD-95 Protein, Rat, Recombinant (His) Rat E. coli
Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain，3 PDZ (DHR) domains and 1 SH3 dom...
TMPH-01746 NOX4 Protein, Human, Recombinant (E. coli, His) Human E. coli
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-00818 Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO) Heteroscodra maculata E. coli
Gating-modifier toxin that potently inhibits inactivation of the mammalian Nav1.1/SCN1A sodium channel (EC(50)=38 nM). Also moderately inhibits inactivation of Nav1.2/SCN2A (EC(50)=236 nM) and Nav1.3/SCN3A (EC(50)=220 nM...
TMPH-01745 NOX4 Protein, Human, Recombinant (Cell-Free, His) Human in vitro E. coli expression system
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-01028 KCNMA1 Protein, Human, Recombinant Human E. coli
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitato...
Cat No. Product Name
L7300 Potassium Channel Blocker Library

160 compounds
A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening;
L7400 Sodium Channel Blocker Library

128 compounds
A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening;

Libraries

Potassium Channel Blocker Library
L7300
Compounds: 160
Sodium Channel Blocker Library
L7400
Compounds: 128
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