Progesterone Receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone. In humans, PR is encoded by a single PGR gene residing on chromosome 11q22, it has two isoforms, PR-A and PR-B, that differ in their molecular weight. The PR-B is the positive regulator of the effects of progesterone, while PR-A serve to antagonize the effects of PR-B.

Cat. No.	Product name	CAS No.	Purity
T17189	U-46619	56985-40-1	98%
T17189	U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (SM...
T5317	Cridanimod	38609-97-1	99.96%
T5317	Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/...
T6819	Desogestrel	54024-22-5	99.96%
T6819	Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
T8395	Nomegestrol acetate	58652-20-3	99.93%
T8395	Nomegestrol acetate is a widely used progestin-like drug,which is characterized as a full agonist at the progesterone receptor
T6713	Ulipristal	159811-51-5	99.9%
T6713	Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.
T0996	Ethynodiol diacetate	297-76-7	99.89%
T0996	Ethynodiol diacetate (Ethynodiol acetate) is a synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive.
T2577	Dienogest	65928-58-7	99.89%
T2577	Dienogest (STS 557) is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory a...
T0478	Progesterone	57-83-0	99.89%
T0478	Progesterone (Pregn-4-ene-3,20-dione) is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on ...
T7537	Norgestimate	35189-28-7	99.87%
T7537	Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.
T1541	Drospirenone	67392-87-4	99.85%
T1541	Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
T5174	Nestoron	7759-35-5	99.83%
T5174	Nestoron (Segesterone Acetate), a synthetic progestin, is a high-affinity agonist of the progesterone receptor (EC50: 10.3 nM).
T60056	Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl-	936345-34-5	99.81%
T60056	Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin e...
T1263	Levonorgestrel	797-63-7	99.79%
T1263	Levonorgestrel (D-Norgestrel) is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum F...
T2527	Ulipristal acetate	126784-99-4	99.79%
T2527	Ulipristal acetate (CDB-2914) is an orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity....
T1429	17α-Hydroxyprogesterone	68-96-2	99.79%
T1429	17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the th...
T3036	Dydrogesterone	152-62-5	99.78%
T3036	Dydrogesterone is a potent progestogen which can be used in progesterone deficiency studies.
T35054	Vilaprisan	1262108-14-4	99.78%
T35054	Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroid...
T1102	Mifepristone	84371-65-3	99.74%
T1102	Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T1284	Megestrol acetate	595-33-5	99.72%
T1284	Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic pr...
T2567	Etonogestrel	54048-10-1	99.69%
T2567	Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.