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Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T14842 BW 245C 72814-32-5 98%
BW 245C
BW 245C is a selective prostaglandin-like DP receptor (DP1) agonist, a prostaglandin analogue with inhibitory effects on the aggregation response of collagen, wh...
TN1171 6-Dehydrogingerdione 76060-35-0 98%
6-Dehydrogingerdione
1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
T8993 BGC201531 1186532-61-5 98%
BGC201531
BGC201531 (AP-1531) is a EP4 antagonist for the treatment of acute migraine.
TN2169 Saikogenin D 5573-16-0 98%
Saikogenin D
Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of...
TN5017 Sideritoflavone 70360-12-2 98%
Sideritoflavone
Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.
TN5011 Shizukaol B 142279-40-1 98%
Shizukaol B
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
T12100 MPGES1-IN-3 1469976-70-2 98%
mPGES1-IN-3
mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .
TN4062 Flavidin 83924-98-5 98%
Flavidin
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
T37991 15-keto Prostaglandin F2α 35850-13-6 98%
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
T14139 Aganepag 910562-18-4 98%
Aganepag
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its a...
TN4748 Penduletin 569-80-2 98%
Penduletin
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
T17092 Tiaprost 71116-82-0 98%
Tiaprost
Tiaprost is a analog of prostaglandin F2α .
T37326 Prostaglandin F2α 1,11-lactone 62410-84-8 98%
Prostaglandin F2α 1,11-lactone
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostagla...
TN1378 α-Viniferin 62218-13-7 98%
α-Viniferin
α-Viniferin known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin has anti-Alzheimer's disease, anti-tuberculosis...
T15642 KAG-308 1215192-68-9 98%
KAG-308
KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP...
TN1009 Epimagnolin B 1134188-26-3 98%
Epimagnolin B
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the s...
TN4463 Lupeolic acid 87355-32-6 98%
Lupeolic acid
Lupeolic acid has anti-inflammatory activity.
TN4064 Flavoglaucin 523-73-9 98%
Flavoglaucin
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
T14146 AGN 210676 910562-15-1 98%
AGN 210676
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
TN4303 Isokaempferide 1592-70-7 98%
Isokaempferide
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
BW 245C
T14842
BW 245C is a selective prostaglandin-like DP receptor (DP1) agonist, a prostaglandin analogue with inhibitory effects on the aggregation response of collagen, wh...
6-Dehydrogingerdione
TN1171
1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
BGC201531
T8993
BGC201531 (AP-1531) is a EP4 antagonist for the treatment of acute migraine.
Saikogenin D
TN2169
Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of...
Sideritoflavone
TN5017
Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro.
Shizukaol B
TN5011
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...
mPGES1-IN-3
T12100
mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .
Flavidin
TN4062
Flavidin shows very good antioxidant capacity. Flavidin can enhance fluorescent imaging, allowing more sensitive and specific cell labeling in tissues, it should...
15-keto Prostaglandin F2α
T37991
15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
Aganepag
T14139
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its a...
Penduletin
TN4748
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
Tiaprost
T17092
Tiaprost is a analog of prostaglandin F2α .
Prostaglandin F2α 1,11-lactone
T37326
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostagla...
α-Viniferin
TN1378
α-Viniferin known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin has anti-Alzheimer's disease, anti-tuberculosis...
KAG-308
T15642
KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP...
Epimagnolin B
TN1009
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the s...
Lupeolic acid
TN4463
Lupeolic acid has anti-inflammatory activity.
Flavoglaucin
TN4064
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannab...
AGN 210676
T14146
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
Isokaempferide
TN4303
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
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TargetMol