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Prostaglandin Receptor

Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for one or more of the classical, naturally occurring prostanoids viz., prostaglandin D2, , PGE2, PGF2alpha, prostacyclin (PGI2), thromboxane A2 (TXA2), and PGH2.[1] They are named based on the prostanoid to which they preferentially bind and respond, e.g. the receptor responsive to PGI2 at lower concentrations than any other prostanoid is named the Prostacyclin receptor (IP). One exception to this rule is the receptor for thromboxane A2 (TP) which binds and responds to PGH2 and TXA2 equally well.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T67958 Pirmagrel 85691-74-3 98.83%
Pirmagrel
pirmagrel is a potent thromboxane synthase inhibitor.
TN3669 Cis-N-Feruloyltyramine 80510-09-4 98.75%
Cis-N-Feruloyltyramine
Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyram...
T23861 CAY10526 938069-71-7 98.75%
CAY10526
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
T2786 Oxysophocarpine 26904-64-3 98.73%
Oxysophocarpine
Oxysophocarpine is extracted from Sophra flavescens Ait.
T5774 Demethylsuberosin 21422-04-8 98.65%
Demethylsuberosin
7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory ...
T36619 Aligeron 70713-45-0 98.57%
Aligeron
Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit P...
T10031 EP1-antagonist-1 851204-35-8 98.51%
EP1-antagonist-1
EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
T3276 Benorilate 5003-48-5 98.39%
Benorilate
Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
TN1524 Continentalic acid 19889-23-7 98.39%
Continentalic acid
Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including the Methicilli...
T63349 Treprostinil diethanolamine 830354-48-8 98.21%
Treprostinil diethanolamine
Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4...
T36683 Vedaprofen 71109-09-6 98.12%
Vedaprofen
Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli slidi...
T14565 BI-671800 1093108-50-9 98.06%
BI-671800
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 n...
TN6647 4-O-Cinnamoylquinic acid 5509-70-6 98.04%
4-O-Cinnamoylquinic acid
4-O-Cinnamoylquinic acid is a small molecule compound extracted from the dried fruits of Casearia grewiifolia, which has an inhibitory effect on prostaglandins a...
TQ0290 ONO-AE3-208 402473-54-5 98.04%
ONO-AE3-208
ONO-AE3-208 (AE 3-208) is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer.
T8993L BGC-20-1531 hydrochloride(1186532-61-5 free base) 1962928-26-2 98.02%
BGC-20-1531 hydrochloride(1186532-61-5 free base)
BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine.
T7652 AM211 1175526-27-8 98%
AM211
AM211 (AM211 free acid) is a potent and orally bioavailable antagonist of prostaglandin D2 (PGD2) receptor type 2 (DP2)
TN1650 Friedelin 559-74-0 98%
Friedelin
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities.
T5847 Cloprostenol sodium salt 55028-72-3 98%
Cloprostenol sodium salt
Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid, is a synthetic analog of prostaglan...
T5758 Sphondin 483-66-9 98%
sphondin
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of...
T3965 Fevipiprant 872365-14-5 98%
Fevipiprant
Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist.
Pirmagrel
T67958
pirmagrel is a potent thromboxane synthase inhibitor.
Cis-N-Feruloyltyramine
TN3669
Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyram...
CAY10526
T23861
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
Oxysophocarpine
T2786
Oxysophocarpine is extracted from Sophra flavescens Ait.
Demethylsuberosin
T5774
7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory ...
Aligeron
T36619
Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit P...
EP1-antagonist-1
T10031
EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
Benorilate
T3276
Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
Continentalic acid
TN1524
Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including the Methicilli...
Treprostinil diethanolamine
T63349
Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4...
Vedaprofen
T36683
Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli slidi...
BI-671800
T14565
BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2). With IC50 values of 4.5 n...
4-O-Cinnamoylquinic acid
TN6647
4-O-Cinnamoylquinic acid is a small molecule compound extracted from the dried fruits of Casearia grewiifolia, which has an inhibitory effect on prostaglandins a...
ONO-AE3-208
TQ0290
ONO-AE3-208 (AE 3-208) is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer.
BGC-20-1531 hydrochloride(1186532-61-5 free base)
T8993L
BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine.
AM211
T7652
AM211 (AM211 free acid) is a potent and orally bioavailable antagonist of prostaglandin D2 (PGD2) receptor type 2 (DP2)
Friedelin
TN1650
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities.
Cloprostenol sodium salt
T5847
Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid, is a synthetic analog of prostaglan...
sphondin
T5758
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of...
Fevipiprant
T3965
Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist.
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TargetMol