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Cat No. | Product Name | Synonyms | Targets |
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T17030 | Tegoprazan | ATPase , Proton pump | |
Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5... | |||
T20626 | Esomeprazole | Proton pump , Cysteine Protease | |
Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI). | |||
T22391 | Omeprazole Sodium | P450 , Proton pump , Antibacterial , Autophagy | |
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive... | |||
T11191 | EN6 | Proton pump , Autophagy | |
EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. EN6 clears TDP-43 aggregates, a causative ... | |||
T16682 | Pumaprazole | BY-841 | Proton pump |
Pumaprazole (BY-841) is an antagonist of a reversible proton pump. | |||
T10435 | Linaprazan | AZD0865 | Potassium Channel |
Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM. | |||
T2188 | Thonzonium Bromide | Proton pump , Antibacterial , Autophagy | |
Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 μM). It inhibits RANKL-induced osteocl... | |||
T8388 | Vonoprazan | TAK-438 (free base) | Proton pump |
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis | |||
T21254 | Vonoprazan Fumarate | TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 | Proton pump |
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19... | |||
T1756L | Ilaprazole | IY81149,IY 81149,IY-81149 | Proton pump , TOPK |
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm... | |||
T0502 | Zinc pyrithione | OM-1563 | Proton pump , Antibacterial , Antifungal |
Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump. | |||
T1756 | Ilaprazole sodium | IY-81149 sodium | Proton pump , TOPK |
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus... | |||
T1651 | Rabeprazole sodium | Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium | Apoptosis , Proton pump |
Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch... | |||
T9230 | KM 91104 | ATPase | |
KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2. | |||
T6700 | Tenatoprazole | TU-199 | Proton pump |
Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM). | |||
T2686L | Esomeprazole Sodium | (S)-Omeprazole sodium | ATPase , Proton pump |
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i... | |||
T1734 | Rabeprazole Sulfide | Rabeprazole Related Compound E | Proton pump , Antibacterial |
Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors. | |||
T0674 | Lansoprazole | A-65006,AG-1749 | Proton pump , Phospholipase , Antibacterial |
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo... | |||
T0757 | Omeprazole | Losec,Prilosec,H 16868,Antra | Proton pump , Phospholipase , Antibacterial , Autophagy |
Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). | |||
T1021 | (R)-Lansoprazole | Dexlansoprazole,T 168390,TAK 390,R-(+)-Lansoprazole | Proton pump |
(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity.Lansoprazole (AG 1749) is a potent brain penetrant neutra... | |||
T2686 | Esomeprazole Magnesium | (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium | ATPase , Proton pump |
Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block... | |||
T6928 | Pantoprazole | SKF96022,BY1023 | Apoptosis , Proton pump , Autophagy |
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T8386 | Esomeprazole Magnesium trihydrate | (S)-Omeprazole magnesium trihydrate | Proton pump |
Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit... | |||
T0161 | Pantoprazole Sodium Hydrate | SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) | Apoptosis , Potassium Channel , Proton pump , Autophagy |
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T6929 | Pantoprazole sodium | Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc | Apoptosis , Others , Proton pump , HIF , Autophagy |
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters... | |||
T5449 | Bamaquimast | F 10126,L 0042 | Proton pump |
Bamaquimast (L 0042) is an inhibitor of proton pump | |||
T29164 | WY-47766 | WY47766 | |
WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis. | |||
T28665 | Saviprazole | Hoe731,Hoe 731,Hoe-731 | Proton pump |
Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer. | |||
T12309 | Omeprazole metabolite Omeprazole sulfone | Omeprazole sulphone,Omeprazole sulfone | Others |
Omeprazole metabolite Omeprazole sulfone can inhibit proton pump. | |||
T2687 | Omeprazole sulfide | Omeprazole metabolite Omeprazole sulfide,Ufiprazole | Proton pump , Drug Metabolite |
Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor. | |||
T23667 | AGN-201904 | AGN201904,AGN 201904 | ATPase |
AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers. | |||
T10138 | 4-Desmethoxy Omeprazole | Drug Metabolite | |
4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM). | |||
T21023 | Bedaquiline fumarate | TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323 | Antibacterial , Antibiotic |
Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ... | |||
T20714 | Levolansoprazole | (S)-Lansoprazole,(-)-Lansoprazole | Proton pump |
Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM). It also inhibits acid formation in isolated canine parietal cells (IC50:... | |||
T10221 | Abeprazan hydrochloride | DWP14012 hydrochloride,Fexuprazan hydrochloride | Proton pump |
Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat... | |||
T28794 | SKF-97574 HCl | SKF97574,SKF-97574,B-9937-051,BY 574,SKF 97574,SK&F-97574 | |
SKF-97574 is proton pump inhibitor. | |||
T11817 | Lansoprazole Sulfide D4 | Proton pump | |
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.La... | |||
T28787 | SK&F-95601 | SK&F 95601,SKF95601,SKF 95601,SKF-95601 | |
F-95601 is a proton pump inhibitor. | |||
T70857 | Scopadulciol | ||
Scopadulciol is and enzyme and proton pump inhibitor. | |||
T70825 | TY 11345 | ||
TY 11345 is a proton pump inhibitor. | |||
T68303 | Esomeprazole strontium | ||
Esomeprazole strontium is a gastric proton pump inhibitor. | |||
T70135 | Nepaprazole sodium dihydrate | ||
Nepaprazole sodium dihydrate is a proton pump inhibitor potentially for treatment of gastric ulcers. | |||
T26727 | Azeloprazole | E-3710,Z215,E3710,Z 215,E 3710,Z-215 | |
Azeloprazole, a proton pump inhibitor, is used potentially for the treatment of gastroesophageal reflux disease (GERD). | |||
T39583 | Zastaprazan | ||
Zastaprazan, a proton pump inhibitor (WO2018008929), is utilized in the research of gastrointestinal inflammatory diseases and conditions related to gastric acid. | |||
T11816 | Lansoprazole-d4 | AG-1749 D4,Lansoprazole D4 | Proton pump |
Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid. | |||
T12308 | Omeprazole-d3 | H 16868 D3 | Others |
Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI) | |||
T68250 | Omeprazole magnesium | ||
Omeprazole magnesium, an orally active proton pump inhibitor (PPI), suppresses gastric acid and is utilized for managing symptoms related to acid reflux and frequent heartburn. | |||
T61445 | Tenatoprazole sodium | ||
Tenatoprazole sodium (TU-199 sodium) is a potent proton pump inhibitor that effectively suppresses the activity of hog gastric H+/K+-ATPase, a vital enzymatic pump involved in acid secretion. It achieves this inhibition ... | |||
T81119 | S-Pantoprazole sodium trihydrate | Proton pump | |
S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a proton pump inhibitor [1]. | |||
T14051 | 5-Hydroxylansoprazole | AG1908 | Proton pump |
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. The metabolism of Lansoprazole occurs through CYP2C19, result... |
Cat No. | Product Name | Synonyms | Targets |
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TQ0184 | Chebulinic acid | ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad | |
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity. | |||
TN1103 | Diphyllin | ATPase , Proton pump , Influenza Virus , HIV Protease | |
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. | |||
T6740 | Bafilomycin A1 | Apoptosis , Proton pump , Antibacterial , Antibiotic , Autophagy | |
Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autopha... | |||
T6368 | Abscisic Acid | Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin) | Others , Proton pump , Endogenous Metabolite |
Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth. | |||
T21651 | Lansoprazole sodium | Lansoprazole (sodium), AG-1749 sodium | Proton pump , Phospholipase , Antibacterial |
Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease. |
Cat No. | Product Name | Species | Expression System |
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TMPH-01892 | ATP4A Protein, Human, Recombinant (His & Myc) | Human | E. coli |
The catalytic subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Uses ATP as an energy source to pump H(+) ions to the gastric ... | |||
TMPH-01893 | ATP4B Protein, Human, Recombinant (GST) | Human | E. coli |
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane... | |||
TMPH-01894 | ATP4B Protein, Human, Recombinant | Human | E. coli |
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane... | |||
TMPH-02310 | ATP6V0D1 Protein, Human, Recombinant (GST) | Human | E. coli |
Subunit of the integral membrane V0 complex of the lysosomal proton-transporting V-type ATPase (v-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providin... | |||
TMPH-00785 | Bacteriorhodopsin Protein, Halobacterium halobium, Recombinant (His & Myc & SUMO) | Halobacterium halobium | E. coli |
Light-driven proton pump. |