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RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T28437 Pomisartan 144702-17-0 99.51%
Pomisartan
Pomisartan (BIBR-363) is a small molecule angiotensin type 1 receptor (AT1R) antagonist that is used in the treatment of cardiovascular disease, studying heart f...
T1484 Perindoprilat 95153-31-4 99.48%
Perindoprilat
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
T1605 Enalapril 75847-73-3 99.47%
Enalapril
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
TP1579 Angiotensin I/II (1-6) 47896-63-9 99.44%
Angiotensin I/II (1-6)
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.
TP1920L1 Acein acetate TP1920L1 99.43%
Acein acetate
Acein acetate is a high affinity ACE ligand (Kd = 2.79 nM). Acein potentiates NMDA+D-serine-induced dopamine release from the striatum.
T13376 YS-49 132836-42-1 99.42%
YS-49
YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).
T9109 SSAA09E2 883944-52-3 99.41%
SSAA09E2
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2...
T5796 Plantainoside D 147331-98-4 99.39%
Plantainoside D
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibit...
T7575L1 [Sar1, Ile8]-Angiotensin II acetate 99.36%
[Sar1, Ile8]-Angiotensin II acetate
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1,...
TP2158L1 TRV-120027 acetate (1234510-46-3 free base) 1824712-70-0 99.34%
TRV-120027 acetate (1234510-46-3 free base)
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
T3461 Losartan Carboxylic Acid 124750-92-1 99.28%
Losartan Carboxylic Acid
Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carbox...
T13865 Resorcinolnaphthalein 41307-63-5 99.25%
Resorcinolnaphthalein
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
T25832 Moveltipril 85856-54-8 99.25%
Moveltipril
Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.
T6716 Valsartan 137862-53-4 99.24%
Valsartan
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
T3281 Delapril hydrochloride 83435-67-0 99.24%
Delapril hydrochloride
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites b...
T13390 ZD 7155 hydrochloride 146709-78-6 99.23%
ZD 7155 hydrochloride
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
T22574L Angiotensin 1/2 (5-7) acetate T22574L 99.13%
Angiotensin 1/2 (5-7) acetate
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is d...
T16116 MLN-4760 305335-31-3 99.05%
MLN-4760
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including ...
T67848 Valsartan Methyl Ester 137863-17-3 98.94%
Valsartan Methyl Ester
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
T7797 Tasosartan 145733-36-4 98.93%
Tasosartan
Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Pomisartan
T28437
Pomisartan (BIBR-363) is a small molecule angiotensin type 1 receptor (AT1R) antagonist that is used in the treatment of cardiovascular disease, studying heart f...
Perindoprilat
T1484
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
Enalapril
T1605
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Angiotensin I/II (1-6)
TP1579
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.
Acein acetate
TP1920L1
Acein acetate is a high affinity ACE ligand (Kd = 2.79 nM). Acein potentiates NMDA+D-serine-induced dopamine release from the striatum.
YS-49
T13376
YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).
SSAA09E2
T9109
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2...
Plantainoside D
T5796
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibit...
[Sar1, Ile8]-Angiotensin II acetate
T7575L1
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1,...
TRV-120027 acetate (1234510-46-3 free base)
TP2158L1
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
Losartan Carboxylic Acid
T3461
Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carbox...
Resorcinolnaphthalein
T13865
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
Moveltipril
T25832
Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.
Valsartan
T6716
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
Delapril hydrochloride
T3281
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites b...
ZD 7155 hydrochloride
T13390
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
Angiotensin 1/2 (5-7) acetate
T22574L
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is d...
MLN-4760
T16116
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including ...
Valsartan Methyl Ester
T67848
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
Tasosartan
T7797
Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
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TargetMol