T61424 |
OD36 hydrochloride
|
2387510-88-3
|
98%
|
|
OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently ...
|
T78597 |
RIPK2-IN-3
|
1290490-78-6
|
98%
|
|
RIPK2-IN-3 (FCG806791773) is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with an IC50 value of 6.39 μM against recombinant truncated RIPK2. It is a...
|
T79041 |
RIP1 kinase inhibitor 4
|
2919836-00-1
|
98%
|
|
RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].
|
T79042 |
RIP1 kinase inhibitor 5
|
2428422-17-5
|
98%
|
|
RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) in suppres...
|
T79043 |
RIP1 kinase inhibitor 6
|
2428401-62-9
|
98%
|
|
RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1 ki...
|
T79044 |
RIP1 kinase inhibitor 7
|
2428401-23-2
|
98%
|
|
RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM. Addition...
|
T79352 |
RIPK2/3-IN-1
|
|
98%
|
|
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3. Additionally, in a 14-TriLAN-G...
|
T81267 |
RIPK3-IN-4
|
2304617-58-9
|
98%
|
|
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage. It alleviates acute kidney injury by atte...
|
T81268 |
RIPK1-IN-17
|
|
98%
|
|
RIPK1/3-IN-1 (Compound 10) is a selective inhibitor of both RIPK1 and RIPK3, effectively preventing necroptosis by blocking the phosphorylation of RIPK1, RIPK3, ...
|
T81269 |
RIPK1-IN-16
|
2561431-77-2
|
98%
|
|
RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo. It shields mi...
|
T73382 |
SZM-1209
|
2919801-86-6
|
98%
|
|
SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM. It demonstrates substantial anti-necropto...
|
T73493 |
RI-962
|
2763831-53-2
|
98%
|
|
RI-962 is a potent and selective inhibitor of receptor-interacting protein kinase 1 (RIPK1), exhibiting an IC50 of 35.0 nM. It is utilized for the investigation ...
|
T73511 |
SZM679
|
T73511
|
98%
|
|
SZM679 is an orally active, selective RIPK1 inhibitor displaying potent affinity with a dissociation constant (Kd) of 8.6 nM for RIPK1, while exhibiting minimal ...
|
T3997 |
WEHI-345
|
1354825-58-3
|
98%
|
|
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.
|
T4074L |
GSK872 HCl(1346546-69-7 free base)
|
2703752-81-0
|
99.82%
|
|
GSK872 HCl(1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM...
|
T6852 |
GSK481
|
1622849-58-4
|
99.71%
|
|
GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.
|
T12730 |
RIPK1-IN-4
|
1481641-08-0
|
99.66%
|
|
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of...
|
T2048 |
LY-364947
|
396129-53-6
|
99.65%
|
|
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
|
T11501 |
GSK840
|
2361146-30-5
|
99.48%
|
|
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase act...
|
T4074 |
GSK-872
|
1346546-69-7
|
99.3%
|
|
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activ...
|