ROS

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen (O2) produces superoxide (•O−2), which is the precursor of most other reactive oxygen species.In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress (e.g., UV or heat exposure), ROS levels can increase dramatically.

Cat. No.	Product name	CAS No.	Purity
T4309	CIL56	300802-28-2	99.91%
T4309	CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumul...
T6947	Piperlongumine	20069-09-4	99.89%
T6947	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (RO...
T1630	Tiopronin	1953-02-2	99.87%
T1630	Tiopronin (Acadione), a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone f...
T4071	Repotrectinib	1802220-02-5	99.86%
T4071	Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respec...
TN1949	Moracin C	69120-06-5	99.86%
TN1949	Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release ...
T10668	Camalexin	135531-86-1	99.84%
T10668	Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce RO...
T2841	Plumbagin	481-42-5	99.82%
T2841	Plumbagin (Plumbaein) is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. I...
T0437	Inosine	58-63-9	99.78%
T0437	Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, ...
TN1725	Hederacolchiside E	33783-82-3	99.78%
TN1725	Hederacolchiside E has antioxidant activity and shows neuroprotective effects in Alzheimer's disease (AD) models via modulating oxidative stress. Hederacolchisid...
T23046	N-tert-butyl-α-Phenylnitrone	3376-24-7	99.69%
T23046	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-...
T8255	(±)-Catechin	7295-85-4	99.69%
T8255	(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.
T24865	Tenivastatin	121009-77-6	99.68%
T24865	Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be us...
TN1146	8-Prenylnaringenin	53846-50-7	99.67%
TN1146	8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,
T8399	Crizotinib hydrochloride	1415560-69-8	99.67%
T8399	Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)
TN1721	Gypenoside L	94987-09-4	99.65%
TN1721	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also i...
T3678	Entrectinib	1108743-60-7	99.61%
T3678	Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1....
T3455	Merestinib	1206799-15-6	99.56%
T3455	Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib...
T3415	Secoisolariciresinol diglucoside	158932-33-3	99.54%
T3415	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglu...
T3S1692	Octahydrocurcumin	36062-07-4	99.54%
T3S1692	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechani...
TN1731	Hernandezine	6681-13-6	99.53%
TN1731	Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.