Ras

Ras is a family of related proteins which is expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily of proteins, which are all related in 3D structure and regulate diverse cell behaviours.

Cat. No.	Product name	CAS No.	Purity
T11778	KRas G12C inhibitor 3	2206735-75-1	98%
T11778	KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.
T11769	KRAS G12C inhibitor 15	2349393-21-9	98%
T11769	KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .
T22991	ML-099	496775-95-2	98%
T22991	pan activator of Ras-related GTPases
T39738	ASP2453	2241719-73-1	98%
T39738	ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf wi...
T20759	XRP44X	729605-21-4	98%
T20759	XRP44X is a potent inhibitor of Ras-Net (Elk-3) pathway.
T24437	MCP110	521310-51-0	98%
T24437	MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.
T5S1261	Methylophiopogonanone B	74805-91-7	98%
T5S1261	1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.
T16432	Pan-RAS-IN-1	1835283-94-7	98%
T16432	Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.
T9407	Rasarfin	674359-73-0
T9407	Rasarfin inhibits Ras and ARF6.
T12979	BI-3406	2230836-55-0	100%
T12979	BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
T3553	Y16	429653-73-6	100%
T3553	Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign...
T8843	APS6-45	2188236-41-9	100%
T8843	APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
T9198	SCH54292	188480-51-5	95.65%
T9198	SCH-54292 is a GDP exchange inhibitor.
T37422L	Ras Inhibitory Peptide acetate		96.63%
T37422L	Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic ...
T7414	ARS-853	1629268-00-3	96.64%
T7414	ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
T5418	BAY-293	2244904-70-7	96.8%
T5418	BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).
T8375	ML-210	1360705-96-9	97%
T8375	ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
T2427	EHop-016	1380432-32-5	97.69%
T2427	EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
T10376	ARS-1630	1698055-86-5	97.81%
T10376	ARS-1630 is a mutant K-ras G12C inhibitor extracted from patent WO 2015054572 A1. It is a less active enantiomer of ARS-1620.
T22249	1588-A4	1698027-20-1	98%
T22249	1588-A4 is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.