Search Result

Search Results for " reactive oxygen species "

Targets

Reactive Oxygen Species Others

218

Compounds

177

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
TP1344	Luciferase		Others
	Luciferase is a flavin-dependent monooxygenase found in bioluminescent bacteria. Luciferase is an invaluable tool for identifying and characterizing functional variants, allowing investigations of gene expression, intrac...		Others
T16951	Sulcotrione		Reactive Oxygen Species
	Sulcotrione is a β-triketone herbicide. It also can inhibit hydroxyphenylpyruvate dioxygenase.		Reactive Oxygen Species
T5426	DMNQ		Reactive Oxygen Species , ROS
	DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation.DMNQ increases ROS generation		Reactive Oxygen Species , ROS
T1710	Trolox		Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species
	Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T15030	CycLuc1		Others
	CycLuc1 is a brain penetrant luciferase substrate. CycLuc1 may be a superior BLI substrate as compared to D-luciferin for monitoring tumor growth of intracranial GBM xenografts.		Others
T3496	Buprofezin	NNI 750,Applaud,Buprofezine	Reactive Oxygen Species
	Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.		Reactive Oxygen Species
T5116	Iprodione		Others , Reactive Oxygen Species , Antifungal
	Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.		Others , Reactive Oxygen Species , Antifungal
T3952	TPEN	TPEDA	Apoptosis , Reactive Oxygen Species , Autophagy
	TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.		Apoptosis , Reactive Oxygen Species , Autophagy
T5966	Hexaconazole	(-)-Hexaconazol	Reactive Oxygen Species , Antifungal
	Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of ...		Reactive Oxygen Species , Antifungal
T19428	Mito-TEMPO		Reactive Oxygen Species , Mitochondrial Metabolism
	Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis.		Reactive Oxygen Species , Mitochondrial Metabolism
T5518	N-acetylcysteine amide		Reactive Oxygen Species , ROS
	N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that can permeate cell membranes and the blood-brain barrier.		Reactive Oxygen Species , ROS
T4168	Visomitin	SKQ1	Reactive Oxygen Species
	Visomitin (SKQ1) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).		Reactive Oxygen Species
T8370	GSK5182		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Reactive Oxygen Species
	GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
T7703	PK11007		Reactive Oxygen Species , p53
	PK11007 is an anti-p53 drug.		Reactive Oxygen Species , p53
T38155	N-Acetyl-D-cysteine		Reactive Oxygen Species
	N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.		Reactive Oxygen Species
T15433	GSK2795039		Apoptosis , Reactive Oxygen Species , ROS , NADPH
	GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).		Apoptosis , Reactive Oxygen Species , ROS , NADPH
T2090	Lexibulin	CYT-997	Apoptosis , Reactive Oxygen Species , Microtubule Associated
	Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this...
T0756	Ethoxyquin	Santoquin,Quinol,Santoflex	HSP , Reactive Oxygen Species
	Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.		HSP , Reactive Oxygen Species
T0418	Allylthiourea	N-Allylthiourea,Thiosinamine	MAO , Reactive Oxygen Species
	Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.		MAO , Reactive Oxygen Species
T8320	J14	J-14	Reactive Oxygen Species
	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death		Reactive Oxygen Species
T17250	W-54011		ROS , Complement System
	W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g...		ROS , Complement System
T13019	Succinyl phosphonate trisodium salt		Dehydrogenase , Reactive Oxygen Species , Endogenous Metabolite
	Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)
T6699	Tempol	TMPN,Tanol,4-Hydroxy-TEMPO	Reactive Oxygen Species , ROS , Autophagy
	Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.		Reactive Oxygen Species , ROS , Autophagy
T8377	Mesotrione		Reactive Oxygen Species
	Mesotrione is a selective triketone herbicide		Reactive Oxygen Species
T4287	Succinobucol	Probucol monosuccinate,AGI-1067	Antioxidant , Reactive Oxygen Species
	Succinobucol (Probucol monosuccinate) is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the heart or coronary ...		Antioxidant , Reactive Oxygen Species
T6482	Efaproxiral Sodium	RSR13 sodium	Reactive Oxygen Species
	Efaproxiral Sodium (RSR13 sodium), a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.		Reactive Oxygen Species
T0163	Nisoldipine	BAY-k 5552	Calcium Channel , Reactive Oxygen Species
	Nisoldipine (BAY-k 5552) is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.		Calcium Channel , Reactive Oxygen Species
T38423	CL097	CL097	Reactive Oxygen Species , TLR
	CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production.		Reactive Oxygen Species , TLR
T7191	Diphenyleneiodonium chloride	DPI	NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel
	Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.
T11580	Heme Oxygenase-1-IN-1	HO-1-IN-1	Reactive Oxygen Species
	Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).		Reactive Oxygen Species
T40612	Manganese(salen) chloride	EUK-8	Others
	Manganese(salen) chloride (EUK-8) (EUK-8) is a superoxide dismutase and catalase mimetic. Manganese(salen) chloride (EUK-8) is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates a...		Others
T15213	Emeramide	BDTH2	Reactive Oxygen Species
	Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator.		Reactive Oxygen Species
T4172	Methoxy-PMS	1-Methoxyphenazine methosulfate,1-Methoxy PMS	Reactive Oxygen Species
	Methoxy-PMS (1-Methoxyphenazine methosulfate) is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.		Reactive Oxygen Species
T2587	Ecabet Sodium	TA-2711E,TA-2711	Reactive Oxygen Species , Antibacterial
	Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.		Reactive Oxygen Species , Antibacterial
T7717	Sodium 2-oxopropanoate	Sodium pyruvate	Reactive Oxygen Species , Endogenous Metabolite
	Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease.		Reactive Oxygen Species , Endogenous Metabolite
T9211	Mito-LND	Mito-Loidamine	OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
	Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T12059L	Mitoquinone mesylate	MitoQ mesylate,MitoQ10 mesylate	Reactive Oxygen Species
	Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.		Reactive Oxygen Species
T21011	Buspirone	Buspirone free base,Ansial	5-HT Receptor
	Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.		5-HT Receptor
T5030	Zofenopril calcium	SQ26991,Zofenopril (calcium)	RAAS , Reactive Oxygen Species
	Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z...		RAAS , Reactive Oxygen Species
T6201	Disufenton sodium	Cerovive,NXY059,OKN007,NXY-059,NXY 059	Reactive Oxygen Species
	Disufenton sodium (NXY-059), a new-type nitrone, exhibits potently neuroprotective effects.		Reactive Oxygen Species
T5363	Tempo	2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T1057	Azilsartan	TAK-536	RAAS
	Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect of azilsartan is by means of Decreased Blood Pres...		RAAS
T3103	L67	DNA Ligase Inhibitor	DNA , DNA/RNA Synthesis
	L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).		DNA , DNA/RNA Synthesis
T15458	H2DCFDA	2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA	Reactive Oxygen Species
	H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) with cell membrane permeability.		Reactive Oxygen Species
T0498	Salsalate	Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171	Reactive Oxygen Species , COX
	Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.		Reactive Oxygen Species , COX
T5016	Tofogliflozin (hydrate)	Tofogliflozin hydrate,CSG-452 hydrate	SGLT , Reactive Oxygen Species , ROS
	Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).		SGLT , Reactive Oxygen Species , ROS
T0860	Mefloquine hydrochloride	Mefloquin hydrochloride,Mefloquine HCl	Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy
	Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T8132	Iron sucrose	Iron saccharate,Sucroferric oxyhydroxide	Reactive Oxygen Species
	Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.		Reactive Oxygen Species
T2132	Buspirone hydrochloride	Buspirone HCl,Narol,Buspar	Dopamine Receptor , 5-HT Receptor
	Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).		Dopamine Receptor , 5-HT Receptor
T0223	Tetrahydroxyquinone	4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone	Apoptosis , Antioxidant , Reactive Oxygen Species
	Tetrahydroxyquinone (Tetroquinone) is a molecule best known as a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle with semiquinone radicals, leading to the formation...		Apoptosis , Antioxidant , Reactive Oxygen Species

Compounds

Target: Reactive Oxygen Species

DMNQ

T5426

Synonym:

Target: Reactive Oxygen Species, ROS

Trolox

T1710

Synonym:

Target: Apoptosis, Antioxidant, Ferroptosis, Reactive Oxygen Species

Synonym: NNI 750,Applaud,Buprofezine

Target: Reactive Oxygen Species

Iprodione

T5116

Synonym:

Target: Others, Reactive Oxygen Species, Antifungal

TPEN

T3952

Synonym: TPEDA

Target: Apoptosis, Reactive Oxygen Species, Autophagy

Hexaconazole

T5966

Synonym: (-)-Hexaconazol

Target: Reactive Oxygen Species, Antifungal

Mito-TEMPO

T19428

Synonym:

Target: Reactive Oxygen Species, Mitochondrial Metabolism

N-acetylcysteine amide

T5518

Synonym:

Target: Reactive Oxygen Species, ROS

Visomitin

T4168

Synonym: SKQ1

Target: Reactive Oxygen Species

GSK5182

T8370

Synonym:

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Reactive Oxygen Species

PK11007

T7703

Synonym:

Target: Reactive Oxygen Species, p53

N-Acetyl-D-cysteine

T38155

Synonym:

Target: Reactive Oxygen Species

GSK2795039

T15433

Synonym:

Target: Apoptosis, Reactive Oxygen Species, ROS, NADPH

Lexibulin

T2090

Synonym: CYT-997

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated

Ethoxyquin

T0756

Synonym: Santoquin,Quinol,Santoflex

Target: HSP, Reactive Oxygen Species

Allylthiourea

T0418

Synonym: N-Allylthiourea,Thiosinamine

Target: MAO, Reactive Oxygen Species

J14

T8320

Synonym: J-14

Target: Reactive Oxygen Species

W-54011

T17250

Synonym:

Target: ROS, Complement System

Succinyl phosphonate trisodium salt

T13019

Synonym:

Target: Dehydrogenase, Reactive Oxygen Species, Endogenous Metabolite

Tempol

T6699

Synonym: TMPN,Tanol,4-Hydroxy-TEMPO

Target: Reactive Oxygen Species, ROS, Autophagy

Mesotrione

T8377

Synonym:

Target: Reactive Oxygen Species

Succinobucol

T4287

Synonym: Probucol monosuccinate,AGI-1067

Target: Antioxidant, Reactive Oxygen Species

Efaproxiral Sodium

T6482

Synonym: RSR13 sodium

Target: Reactive Oxygen Species

Nisoldipine

T0163

Synonym: BAY-k 5552

Target: Calcium Channel, Reactive Oxygen Species

CL097

T38423

Synonym: CL097

Target: Reactive Oxygen Species, TLR

Diphenyleneiodonium chloride

T7191

Synonym: DPI

Target: NOS, Reactive Oxygen Species, NADPH, TRP/TRPV Channel

Heme Oxygenase-1-IN-1

T11580

Synonym: HO-1-IN-1

Target: Reactive Oxygen Species

Manganese(salen) chloride

Target: Reactive Oxygen Species

Methoxy-PMS

T4172

Synonym: 1-Methoxyphenazine methosulfate,1-Methoxy PMS

Target: Reactive Oxygen Species

Ecabet Sodium

T2587

Synonym: TA-2711E,TA-2711

Target: Reactive Oxygen Species, Antibacterial

Sodium 2-oxopropanoate

T7717

Synonym: Sodium pyruvate

Target: Reactive Oxygen Species, Endogenous Metabolite

Mito-LND

T9211

Synonym: Mito-Loidamine

Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy

Mitoquinone mesylate

T12059L

Synonym: MitoQ mesylate,MitoQ10 mesylate

Target: Reactive Oxygen Species

Buspirone

T21011

Synonym: Buspirone free base,Ansial

Target: 5-HT Receptor

Zofenopril calcium

T5030

Synonym: SQ26991,Zofenopril (calcium)

Target: RAAS, Reactive Oxygen Species

Disufenton sodium

T6201

Synonym: Cerovive,NXY059,OKN007,NXY-059,NXY 059

Target: Reactive Oxygen Species

Tempo

T5363

Synonym: 2,2,6,6-Tetramethylpiperidinooxy

Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism

Synonym: DNA Ligase Inhibitor

Target: DNA, DNA/RNA Synthesis

H2DCFDA

T15458

Synonym: 2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA

Target: Reactive Oxygen Species

Salsalate

T0498

Synonym: Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171

Target: Reactive Oxygen Species, COX

Tofogliflozin (hydrate)

T5016

Synonym: Tofogliflozin hydrate,CSG-452 hydrate

Target: SGLT, Reactive Oxygen Species, ROS

Mefloquine hydrochloride

T0860

Synonym: Mefloquin hydrochloride,Mefloquine HCl

Target: Potassium Channel, SARS-CoV, Reactive Oxygen Species, Parasite, Autophagy

Iron sucrose

T8132

Synonym: Iron saccharate,Sucroferric oxyhydroxide

Target: Reactive Oxygen Species

Buspirone hydrochloride

T2132

Synonym: Buspirone HCl,Narol,Buspar

Target: Dopamine Receptor, 5-HT Receptor

Tetrahydroxyquinone

T0223

Synonym: 4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Cat No.	Product Name	Synonyms	Targets
TQ0212	Glucoraphanin		Antioxidant , Reactive Oxygen Species
	Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.		Antioxidant , Reactive Oxygen Species
T1716	Echinacoside		Reactive Oxygen Species , Wnt/beta-catenin
	Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat...		Reactive Oxygen Species , Wnt/beta-catenin
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...
T16747	Riboflavin Tetrabutyrate		Reactive Oxygen Species
	Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.		Reactive Oxygen Species
T6S2038	Ziyuglycoside II		Apoptosis , Antioxidant , Reactive Oxygen Species
	1. Ziyuglycoside II has anti-inflammation and antioxidation properties. 2. Ziyuglycoside II has antibiosis, and homeostasis properties. 3. Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer ...		Apoptosis , Antioxidant , Reactive Oxygen Species
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T3399	Psoralidin		Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial
	Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T2866	Echinocystic acid		Apoptosis , Antioxidant , Reactive Oxygen Species
	Echinocystic acid (EA), a natural triterpone enriched in various herbs, shows a range of pharmacological activities including anti-inflammatory and antioxidant effects.		Apoptosis , Antioxidant , Reactive Oxygen Species
T2818	Methyl Vanillate		Reactive Oxygen Species , Wnt/beta-catenin , Endogenous Metabolite
	Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightl...
TN1403	Arjunolic acid		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
	Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim...
TN2167	Rutaevin		Reactive Oxygen Species , NO Synthase
	Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent.		Reactive Oxygen Species , NO Synthase
T8033	Sodium Thiocyanate		Others , Reactive Oxygen Species , Interleukin
	Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals.		Others , Reactive Oxygen Species , Interleukin
T9057	Norbergenin		IL Receptor , TNF , Reactive Oxygen Species
	Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi.		IL Receptor , TNF , Reactive Oxygen Species
T10668	Camalexin		Reactive Oxygen Species , ROS , Antibacterial , Antifungal
	Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.
TN1674	Garcinone D		Reactive Oxygen Species , Nrf2 , STAT
	Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti...		Reactive Oxygen Species , Nrf2 , STAT
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
TN6735	Bigelovin		Apoptosis , Reactive Oxygen Species , Retinoid Receptor , Autophagy , RAR/RXR
	Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a pote...
T36735	3,5-Di-tert-butylphenol		Reactive Oxygen Species , Antifungal
	3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.		Reactive Oxygen Species , Antifungal
T8347	Rifamycin S		Reactive Oxygen Species , ROS , Antibacterial , Antibiotic
	Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria
T3332	Isosteviol	(-)-Isosteviol	IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
	Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
TN5634	Aureusidin	Auresudidin,Auresidin	Antioxidant , Reactive Oxygen Species , Lipoxygenase
	Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.		Antioxidant , Reactive Oxygen Species , Lipoxygenase
T0465	Ellagic acid	Gallogen,Elagostasine	Hedgehog/Smoothened , Casein Kinase , Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , PKA , Syk , PKC , Carbonic Anhydrase
	Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used...
T2174	Quercetin	Sophoretin	Apoptosis , Mitophagy , Reactive Oxygen Species , PI3K , Autophagy
	Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1. Quercetin is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ (IC50=2.4/3.0/5.4 μM). Quercetin can induce apoptosis and autophagy.
TN1651	Furanodiene		Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp
	Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
T3861	Isobavachalcone	Corylifolinin,Isobacachalcone	Apoptosis , Others , Reactive Oxygen Species , Akt , Autophagy
	Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation.
T2864	Lycopene	ψ,ψ-Carotene	Reactive Oxygen Species , ROS
	Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids ...		Reactive Oxygen Species , ROS
T6947	Piperlongumine	PPLGM,Piplartine	Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy
	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
T2834	Nobiletin	Hexamethoxyflavone	Apoptosis , MMP , Reactive Oxygen Species , ROR , Autophagy
	Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic...
T6S1653	Albiflorin	Alibiflorin	Reactive Oxygen Species
	1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...		Reactive Oxygen Species
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
T41358	2-Hydroxybenzylamine		Others
	2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a...		Others
T3429	Protopine	Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine	Reactive Oxygen Species , Platelet aggregation , Histamine Receptor
	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
T8072	S-Methyl-L-cysteine	S-Methylcysteine	Antioxidant , Reactive Oxygen Species
	S-Methyl-L-cysteine (S-Methylcysteine) is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with neuroprotective, antioxidative, and anti-...		Antioxidant , Reactive Oxygen Species
T0480	Doxofylline	Doxophylline	PDE , Adenosine Receptor
	Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s...		PDE , Adenosine Receptor
T3240	Citronellol	dihydrogeraniol,(±)-β-Citronellol	Reactive Oxygen Species
	Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.		Reactive Oxygen Species
T7781	Reynoutrin	Reinutrin,Quercetin-3-D-xyloside	Reactive Oxygen Species
	Reynoutrin (Reinutrin) with antioxidant and radical-scavenging activity.		Reactive Oxygen Species
T5852	Canthaxanthin	all-trans-Canthaxanthin,E 161g	Reactive Oxygen Species
	Canthaxanthin (E 161g) is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.		Reactive Oxygen Species
T3744	Veratric acid	Veratrumenoic acid,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species , COX
	Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.		Reactive Oxygen Species , COX
T2992	Pinocembrin	5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone	NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
	Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.
T5A2461	Bufotalin	Bufotaline	Apoptosis , Others , Reactive Oxygen Species
	1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.		Apoptosis , Others , Reactive Oxygen Species
TN1141	Isodeoxyelephantopin		NF-κB , Reactive Oxygen Species , Autophagy
	Isodeoxyelephantopin exerts antitumor effects on several cancer cells by inducing apoptosis , cell cycle arrest , and inhibiting proliferation. It enhances apoptosis and inhibit invasion and osteoclastogenesis by inhibit...		NF-κB , Reactive Oxygen Species , Autophagy
T2796	Coenzyme Q10	Ubiquinone-10,CoQ10	Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite
	Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T3S1089	Phillygenin	Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol	Reactive Oxygen Species
	1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.		Reactive Oxygen Species
T8693	Diallyl Trisulfide		Apoptosis , Reactive Oxygen Species , Antifungal
	Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.		Apoptosis , Reactive Oxygen Species , Antifungal
T1717	Alpha-Mangostin	α-Mangostin,Mangostin	Apoptosis , Virus Protease , Dehydrogenase , Reactive Oxygen Species , Antibacterial , Antifungal
	alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
T3785	11-oxo-mogroside V	11-oxo Mogroside V	Reactive Oxygen Species
	11-oxo-mogroside V (11-oxo Mogroside V) is a sweet tasting cucurbitane glycoside derivative of mogroside V. It has antioxidant effects against both O2- and OH- and prevents OH-induced DNA damage.		Reactive Oxygen Species
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T0928	L-Ascorbic acid	Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate	Apoptosis , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
	L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-...
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Natural Products

Glucoraphanin

TQ0212

Synonym:

Target: Antioxidant, Reactive Oxygen Species

Echinacoside

T1716

Synonym:

Target: Reactive Oxygen Species, Wnt/beta-catenin

Octahydrocurcumin

T3S1692

Synonym:

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

Riboflavin Tetrabutyrate

T16747

Synonym:

Target: Reactive Oxygen Species

Ziyuglycoside II

T6S2038

Synonym:

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Hexahydrocurcumin

TQ0288

Synonym:

Target: Reactive Oxygen Species, ROS, COX

Psoralidin

T3399

Synonym:

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Echinocystic acid

T2866

Synonym:

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Methyl Vanillate

T2818

Synonym:

Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite

Arjunolic acid

TN1403

Synonym:

Target: IL Receptor, TNF, Reactive Oxygen Species, JNK, AChE

Rutaevin

TN2167

Synonym:

Target: Reactive Oxygen Species, NO Synthase

Sodium Thiocyanate

T8033

Synonym:

Target: Others, Reactive Oxygen Species, Interleukin

norbergenin

T9057

Synonym:

Target: IL Receptor, TNF, Reactive Oxygen Species

Camalexin

T10668

Synonym:

Target: Reactive Oxygen Species, ROS, Antibacterial, Antifungal

Garcinone D

TN1674

Synonym:

Target: Reactive Oxygen Species, Nrf2, STAT

Pelargonidin chloride

TN1058

Synonym:

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

Bigelovin

TN6735

Synonym:

Target: Apoptosis, Reactive Oxygen Species, Retinoid Receptor, Autophagy, RAR/RXR

3,5-Di-tert-butylphenol

T36735

Synonym:

Target: Reactive Oxygen Species, Antifungal

Rifamycin S

T8347

Synonym:

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

Isosteviol

T3332

Synonym: (-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Aureusidin

TN5634

Synonym: Auresudidin,Auresidin

Target: Antioxidant, Reactive Oxygen Species, Lipoxygenase

Ellagic acid

T0465

Synonym: Gallogen,Elagostasine

Target: Hedgehog/Smoothened, Casein Kinase, Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, PKA, Syk, PKC, Carbonic Anhydrase

Quercetin

T2174

Synonym: Sophoretin

Target: Apoptosis, Mitophagy, Reactive Oxygen Species, PI3K, Autophagy

Furanodiene

TN1651

Synonym:

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

Isobavachalcone

T3861

Synonym: Corylifolinin,Isobacachalcone

Target: Apoptosis, Others, Reactive Oxygen Species, Akt, Autophagy

Lycopene

T2864

Synonym: ψ,ψ-Carotene

Target: Reactive Oxygen Species, ROS

Piperlongumine

T6947

Synonym: PPLGM,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

Nobiletin

T2834

Synonym: Hexamethoxyflavone

Target: Apoptosis, MMP, Reactive Oxygen Species, ROR, Autophagy

Albiflorin

T6S1653

Synonym: Alibiflorin

Target: Reactive Oxygen Species

Synonym: Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine

Target: Reactive Oxygen Species, Platelet aggregation, Histamine Receptor

Uric Acid

T0626

Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

S-Methyl-L-cysteine

T8072

Synonym: S-Methylcysteine

Target: Antioxidant, Reactive Oxygen Species

Doxofylline

T0480

Synonym: Doxophylline

Target: PDE, Adenosine Receptor

Citronellol

T3240

Synonym: dihydrogeraniol,(±)-β-Citronellol

Target: Reactive Oxygen Species

Reynoutrin

T7781

Synonym: Reinutrin,Quercetin-3-D-xyloside

Target: Reactive Oxygen Species

Canthaxanthin

T5852

Synonym: all-trans-Canthaxanthin,E 161g

Target: Reactive Oxygen Species

Veratric acid

T3744

Synonym: Veratrumenoic acid,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Pinocembrin

T2992

Synonym: 5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone

Target: NF-κB, Reactive Oxygen Species, Antibacterial, Autophagy

Bufotalin

T5A2461

Synonym: Bufotaline

Target: Apoptosis, Others, Reactive Oxygen Species

Isodeoxyelephantopin

TN1141

Synonym:

Target: NF-κB, Reactive Oxygen Species, Autophagy

Coenzyme Q10

T2796

Synonym: Ubiquinone-10,CoQ10

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite

Sinapinic Acid

T3753

Synonym: Sinapic acid,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Phillygenin

T3S1089

Synonym: Epipinoresinol methyl ether,(+)-Phillygenin,Phillygenol,Sylvatesmin,Forsythigenol

Target: Reactive Oxygen Species

Diallyl Trisulfide

T8693

Synonym:

Target: Apoptosis, Reactive Oxygen Species, Antifungal

alpha-Mangostin

T1717

Synonym: α-Mangostin,Mangostin

Target: Apoptosis, Virus Protease, Dehydrogenase, Reactive Oxygen Species, Antibacterial, Antifungal

11-oxo-mogroside V

T3785

Synonym: 11-oxo Mogroside V

Target: Reactive Oxygen Species

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

L-Ascorbic acid

T0928

Synonym: Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-02198	TXNRD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
TMPH-00099	NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	Yeast
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a...
TMPY-02044	SOD2 Protein, Human, Recombinant	Human	E. coli
	Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is locat...
TMPK-00493	OSMR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and prom...
TMPK-00571	OSMR Protein, Canine, Recombinant (His)	Canine	HEK293
	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and prom...
TMPJ-00753	Myoglobin Protein, Human, Recombinant (His)	Human	E. coli
	Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as...
TMPH-02875	ROMO1 Protein, Mouse, Recombinant (His)	Mouse	in vitro E. coli expression system
	Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are n...
TMPH-02106	SH3PXD2A Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides...
TMPH-02104	Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may al...
TMPH-02470	PDK3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and incre...
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidat...
TMPJ-01274	ERO1L Protein, Human, Recombinant (His)	Human	Human Cells
	ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endopl...
TMPJ-00931	Serpin A4 Protein, Human, Recombinant (His)	Human	Human Cells
	Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec...
TMPH-01745	NOX4 Protein, Human, Recombinant (Cell-Free, His)	Human	in vitro E. coli expression system
	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-01746	NOX4 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-01688	UCP1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and...
TMPJ-00933	PRDX5 Protein, Human, Recombinant (His)	Human	Human Cells
	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox...
TMPH-02585	ACOD1 Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus
	Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna...
TMPJ-00848	NCF1 Protein, Human, Recombinant (His)	Human	E. coli
	Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem...
TMPH-01687	UCP1 Protein, Human, Recombinant (His)	Human	Yeast
	Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and...
TMPH-01098	ACOD1 Protein, Human, Recombinant (His)	Human	E. coli
	Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna...
TMPY-05001	MPZL3 Protein, Human, Recombinant (His)	Human	HEK293
	MPZL3 (Myelin Protein Zero Like 3) is a Protein Coding gene. The encoded protein belongs to the myelin P0 protein family. MPZL3 is broadly expressed in skin, esophagus, and other tissues. MPZL3 was essential for normal d...
TMPH-02930	TREX1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA f...
TMPH-02201	TREX1 Protein, Human, Recombinant (His & MBP)	Human	Baculovirus
	Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA f...
TMPY-02401	Tyrosine Hydroxylase Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw...
TMPY-02587	Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw...
TMPH-01739	NLRP3 Protein, Human, Recombinant (His)	Human	E. coli
	As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polym...
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e...
TMPH-00855	RPS3 Protein, Human, Recombinant (His)	Human	E. coli
	Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad spe...
TMPH-01788	NFE2L2 Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter region of many cytoprotective genes, such as phase 2 detoxifying enzyme...
TMPH-00297	S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)	Bovine	E. coli
	S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal act...
TMPH-03256	CNR1 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effe...
TMPH-02631	PRKN Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-01045	CEACAM1 Protein, Human, Recombinant	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPH-01263	PRKN Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-01035	CNR1 Protein-VLP, Human, Recombinant (His)	Human	HEK293
	G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrah...
TMPH-03281	PRKN Protein, Rat, Recombinant (His & Myc)	Rat	Baculovirus
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-01044	CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPH-01262	PRKN Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...

TXNRD2 Protein, Human, Recombinant (His & SUMO)

TMPH-02198

Species: Human

Expression System: E. coli

NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00099

Species: Arabidopsis thaliana

Expression System: Yeast

SOD2 Protein, Human, Recombinant

TMPY-02044

Species: Human

Expression System: E. coli

OSMR Protein, Cynomolgus, Recombinant (His)

TMPK-00493

Species: Cynomolgus

Expression System: HEK293

OSMR Protein, Canine, Recombinant (His)

TMPK-00571

Species: Canine

Expression System: HEK293

Myoglobin Protein, Human, Recombinant (His)

TMPJ-00753

Species: Human

Expression System: E. coli

ROMO1 Protein, Mouse, Recombinant (His)

TMPH-02875

Species: Mouse

Expression System: in vitro E. coli expression system

SH3PXD2A Protein, Human, Recombinant (His & Myc)

TMPH-02106

Species: Human

Expression System: E. coli

Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)

TMPH-02104

Species: Human

Expression System: E. coli

PDK3 Protein, Mouse, Recombinant (His)

TMPH-02470

Species: Mouse

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

TMPY-02271

Species: Human

Expression System: E. coli

ERO1L Protein, Human, Recombinant (His)

TMPJ-01274

Species: Human

Expression System: Human Cells

Serpin A4 Protein, Human, Recombinant (His)

TMPJ-00931

Species: Human

Expression System: Human Cells

NOX4 Protein, Human, Recombinant (Cell-Free, His)

TMPH-01745

Species: Human

Expression System: in vitro E. coli expression system

NOX4 Protein, Human, Recombinant (E. coli, His)

TMPH-01746

Species: Human

Expression System: E. coli

UCP1 Protein, Human, Recombinant (His & SUMO)

TMPH-01688

Species: Human

Expression System: E. coli

PRDX5 Protein, Human, Recombinant (His)

TMPJ-00933

Species: Human

Expression System: Human Cells

ACOD1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02585

Species: Mouse

Expression System: Baculovirus

NCF1 Protein, Human, Recombinant (His)

TMPJ-00848

Species: Human

Expression System: E. coli

UCP1 Protein, Human, Recombinant (His)

TMPH-01687

Species: Human

Expression System: Yeast

ACOD1 Protein, Human, Recombinant (His)

TMPH-01098

Species: Human

Expression System: E. coli

MPZL3 Protein, Human, Recombinant (His)

TMPY-05001

Species: Human

Expression System: HEK293

TREX1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02930

Species: Mouse

Expression System: E. coli

TREX1 Protein, Human, Recombinant (His & MBP)

TMPH-02201

Species: Human

Expression System: Baculovirus

Tyrosine Hydroxylase Protein, Human, Recombinant (His)

TMPY-02401

Species: Human

Expression System: Baculovirus-Insect Cells

Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)

TMPY-02587

Species: Mouse

Expression System: Baculovirus-Insect Cells

NLRP3 Protein, Human, Recombinant (His)

TMPH-01739

Species: Human

Expression System: E. coli

ACAT2 Protein, Rat, Recombinant (His)

TMPY-04813

Species: Rat

Expression System: E. coli

RPS3 Protein, Human, Recombinant (His)

TMPH-00855

Species: Human

Expression System: E. coli

NFE2L2 Protein, Human, Recombinant (His)

TMPH-01788

Species: Human

Expression System: E. coli

S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)

TMPH-00297

Species: Bovine

Expression System: E. coli

CNR1 Protein, Rat, Recombinant (His)

TMPH-03256

Species: Rat

Expression System: in vitro E. coli expression system

PRKN Protein, Mouse, Recombinant (GST)

TMPH-02631

Species: Mouse

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant

TMPH-01045

Species: Human

Expression System: E. coli

PRKN Protein, Human, Recombinant (His & SUMO)

TMPH-01263

Species: Human

Expression System: E. coli

CNR1 Protein-VLP, Human, Recombinant (His)

TMPH-01035

Species: Human

Expression System: HEK293

PRKN Protein, Rat, Recombinant (His & Myc)

TMPH-03281

Species: Rat

Expression System: Baculovirus

CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01044

Species: Human

Expression System: E. coli

PRKN Protein, Human, Recombinant (His & Myc)

TMPH-01262

Species: Human

Expression System: Baculovirus

Cat No.	Product Name
L2910	Antioxidant Compound Library	1330 compounds
	Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L5300	Mitochondria-Targeted Compound Library	830 compounds
	A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;

Libraries

Antioxidant Compound Library

L2910

Compounds: 1330

Mitochondria-Targeted Compound Library

L5300

Compounds: 830