Retinoid Receptor

Cat No.	product name
T1002	Etodolac	Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, ...
T1051	Tretinoin	Tretinoin binds to and activates retinoic acid receptors (RARs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell p...
T1093	Adapalene	Adapalene is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.
T1288	TTNPB	TTNPB, a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM), respectively.
T1330	Acitretin	Acitretin is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
T1611	Isotretinoin	Isotretinoin binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and ...
T1872	Fenretinide	Fenretinide is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.
T3955	AR7	AR7 is a retinoic acid receptor α (RARα) antagonist.
T6410	Bexarotene	Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
T6694	Tamibarotene	Tamibarotene is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity.
T6696	Tazarotene	Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazar...
T6831	Etretinate	Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an ind...
T4371	CD437	CD437 is a specifc Retinoic Acid Receptor γ (RARγ) agonist.
T4538	palovarotene	Palovarotene is an agonist of nuclear retinoic acid receptor γ (RAR-γ).
T5341	WYC209	WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
T5854	AM580	AM580 is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )
T5843	R-flurbiprofen	R-flurbiprofen is the non-cyclooxygenase inhibiting R-enantiomer of the non-steroidal anti-inflammatory drug flurbiprofen, which was assessed as a remedy for Al...
TQ0064	Peretinoin	Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.
TQ0097	AGN 193109	AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
T3000	Magnolol	Magnolol is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T14143	AGN 194310	AGN 194310 (VTP-194310) is retinioic acid receptors (RARs) pan-antagonist. The Kd values of 3 nM, 2 nM, 5 nM for RARα, RARβ, RARγ, respectively[1][2].
T14689	BMS493	BMS493 is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 also could prevent retinoic acid-induced differentiation. BMS493 increases nuclear corepre...
T14911	CD2665	CD2665 is an antagonist of RAR-beta/gamma (Ki: 110 nM and 306 nM for RARγ and RARβ).
T14912	CD3254	CD3254 a selective agonist of retinoid-X-receptor (RXR).
T14946	Ch55	Ch55 is a potent inducer of the differentiation of HL60 cells (EC50: 200 nM). Ch55 binds to RAR-α and RAR-β receptors with high affinity. Ch55 shows a low aff...
T15825	LY 178002	LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production ...
T16425	PA452	PA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.
T11844	LG-100064	LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)