Reverse Transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases are used by retroviruses to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes, and by some non-retroviruses such as the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses.

Cat No.	product name
T0153	Oltipraz	Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as ...
T0220	Foscarnet sodium	Foscarnet sodium is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
T0682	Lamivudine	Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HI...
T0753	Salicylanilide	Salicylanilides are a group of compounds with antiviral potency, antibacterial and antifungal activities.
T11189	Emtricitabine S-oxide	Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.Emtricitabine S-oxide (Emtricitabine sulfoxide) is ...
T1404	Stavudine	Stavudine, a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T1416	Zidovudine	Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the ...
T1513	Telbivudine	Telbivudine is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcri...
T15784	LP99	LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9...
T1649	Tenofovir	Tenofovir is an adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHR...
T1675	Adefovir dipivoxil	Adefovir Dipivoxil is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B vi...
T2330	Rilpivirine	Rilpivirine is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infe...
T2409	Tenofovir alafenamide	Tenofovir Alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.
T2551	Etravirine	Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that co...
T2578	Didanosine	Didanosine is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).
T3730	Methyl gallate	Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
T6214	Emtricitabine	Emtricitabine (FTC)， a nucleoside reverse transcriptase inhibitor， exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B v...

Cat No.

product name

T0153

Oltipraz

Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as ...

T0220

Foscarnet sodium

Foscarnet sodium is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.

T0682

Lamivudine

Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HI...

T0753

Salicylanilide

Salicylanilides are a group of compounds with antiviral potency, antibacterial and antifungal activities.

T11189

Emtricitabine S-oxide

Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.Emtricitabine S-oxide (Emtricitabine sulfoxide) is ...

T1404

Stavudine

Stavudine, a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.

T1416

Zidovudine

Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the ...

T1513

Telbivudine

Telbivudine is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcri...

T15784

LP99

LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9...

T1649

Tenofovir

Tenofovir is an adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHR...

T1675

Adefovir dipivoxil

Adefovir Dipivoxil is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B vi...

T2330

Rilpivirine

Rilpivirine is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infe...

T2409

Tenofovir alafenamide

Tenofovir Alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.

T2551

Etravirine

Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that co...

T2578

Didanosine

Didanosine is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).

T3730

Methyl gallate

Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.

T6214

Emtricitabine

Emtricitabine (FTC)， a nucleoside reverse transcriptase inhibitor， exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B v...