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Microbiology/Virology SARS-CoV

SARS-CoV

Cat No. product name
T8689 CHLOROQUINE Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria an...
T12502 PLpro inhibitor PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
T11464 GRL0617 GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
T3S0136 O-Methylbroussochalcone B 4'-O-Methylbavachalcone is isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) ac...
T8688 CPD77 CPD77 is a potent SARS-​CoV-​2 main protease inhibitor.
T8419 XP-59 XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
T8371 ML188 ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
T8309 EIDD-2801 EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviru...
T7766 Remdesivir Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)
CHLOROQUINE
T8689CAS 54-05-7
Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria an...
PLpro inhibitor
T12502CAS 1093070-14-4
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
GRL0617
T11464CAS 1093070-16-6
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
O-Methylbroussochalcone B
T3S0136CAS 20784-60-5
4'-O-Methylbavachalcone is isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) ac...
CPD77
T8688CAS 2144491-78-9
CPD77 is a potent SARS-​CoV-​2 main protease inhibitor.
XP-59
T8419CAS 890402-73-0
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
ML188
T8371CAS 1417700-13-0
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
EIDD-2801
T8309CAS 2349386-89-4
EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviru...
Remdesivir
T7766CAS 1809249-37-3
Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)