SARS-CoV

Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1) is a strain of virus that causes severe acute respiratory syndrome (SARS). It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the ACE2 receptor. It infects humans, bats, and palm civets.

Cat. No.	Product name	CAS No.	Purity	Chemical Structure
T5539	GS-443902	1355149-45-9
T5539	GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
T78252	Bebtelovimab	2578319-11-4	98%	Bebtelovimab
T78252	Bebtelovimab is a humanized IgG1-λ2 antibody specifically targeting SARS-CoV-2 and has demonstrated potent neutralization against its variants, exhibiting mild-t...			Bebtelovimab
T78659	Crexavibart	2599039-61-7	98%	Crexavibart
T78659	Crexavibart (BMS-986413; C-144-LS), an IgG1 λ2 antibody, specifically targets the receptor-binding domain of the SARS-CoV-2 spike (S) glycoprotein [1].			Crexavibart
T78704	PLpro/RBD-IN-1	1282451-83-5	98%
T78704	PLpro/RBD-IN-1 (Compound 5) serves as a dual inhibitor targeting both the SARS-CoV-2 papain-like protease (PLpro) and the receptor-binding domain (RBD) of the sp...
T78713	SARS-CoV-2-IN-40		98%
T78713	SARS-CoV-2-IN-40 (Compound 19), a SARS-CoV-2 inhibitor, effectively suppresses the infection of Calu3 lung cells by the BA.1 and BA.5 variants, exhibiting half-m...
T78719	SARS-CoV-2-IN-47		98%
T78719	SARS-CoV-2-IN-47 (Compound 13), with IC50 values of 0.77 μM against Omicron BA.1 and 0.93 μM against the Delta strain, serves as an inhibitor of SARS-CoV-2 and i...
T78720	SARS-CoV-2-IN-48		98%
T78720	SARS-CoV-2-IN-48 (compound 19) is an inhibitor of SARS-CoV-2, exhibiting an IC50 of 2.7 μM against the Omicron BA.1 variant and demonstrating antiviral activitie...
T78722	ZINC475239213	2871002-89-8	98%
T78722	ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 μM [1].
T78723	ZINC61142882		98%
T78723	ZINC61142882 is a SARS-CoV-2 Nsp14 N7-Methyltransferase inhibitor with an IC50 value of 6 μM [1].
T78724	Acryl42-10		98%
T78724	Acryl42-10 serves as a covalent inhibitor for the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an inhibition concentration (IC50) of 7 μM [1].
T78725	SARS-CoV-2 nsp14-IN-3	2920574-16-7	98%
T78725	SARS-CoV-2 nsp14-IN-3 (4975) is a potent inhibitor targeting the N7-Methyltransferase activity of SARS-CoV-2 nonstructural protein 14 (Nsp14), with an IC50 value...
T78726	Z795161988		98%
T78726	Z795161988 functions as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase, exhibiting an inhibitory concentration (IC50) of 2.2 μM [1].
T78760	MTase-IN-1		98%
T78760	MTase-IN-1 (compound 26), a potent and selective inhibitor of coronavirus nsp14 N7-methyltransferases, exhibits an IC50 of 0.72 nM. It disrupts viral RNA transla...
T78765	SARS-CoV-2-IN-51		98%
T78765	SARS-CoV-2-IN-51 (S-10), a lead compound for Omicron fusion inhibition, demonstrates potent activity against Omicron and other SARS-CoV-2 variants, with EC50 val...
T78867	WU-04	2921711-74-0	98%
T78867	WU-04 is a non-covalent inhibitor targeting the 3CLpro protein of SARS-CoV-2, demonstrating high inhibitory effects on 3CLpro from six SARS-CoV-2 variants (Alpha...
T78895	TKB245	2892688-16-1	98%
T78895	TKB245 is a potent inhibitor of the SARS-CoV-2 main protease (Mpro), effectively inhibiting viral replication in VeroE6 cells [1].
T78926	SARS-CoV-2-IN-42		98%
T78926	SARS-CoV-2-IN-42 (Compound 8q) effectively inhibits SARS-CoV-2 replication with an EC50 value of 0.4 μM and demonstrates no significant toxicity to the host cell...
T78953	SIMR3030	2708270-99-7	98%
T78953	SIMR3030, a potent inhibitor of SARS-CoV-2 PLpro, possesses an IC50 of 0.0399 µg/mL and demonstrates antiviral activity by diminishing the expression of SARS-CoV...
T78961	SARS-CoV-2-IN-38	2882823-27-8	98%
T78961	SARS-CoV-2-IN-38, also known as compound 24, is an inhibitor of SARS-CoV-2 that demonstrates favorable oral bioavailability in mice, with an absorption fraction ...
T79218	SARS-CoV-2-IN-41	2920904-06-7	98%
T79218	SARS-CoV-2-IN-41 (compound 2) is a potent inhibitor of SARS-CoV-2 3CL protease, exhibiting an IC50 of 0.022 µM and demonstrating antiviral efficacy [1].