T8419 |
XP-59
|
890402-73-0
|
100%
|
|
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
|
T8309 |
EIDD-2801
|
2349386-89-4
|
100%
|
|
EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronavirus...
|
T3089 |
6-Thioguanine
|
154-42-7
|
100%
|
|
Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
|
T5863 |
Indinavir sulfate
|
157810-81-6
|
100%
|
|
Indinavir is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
|
TP1016L |
Aviptadil Acetate
|
1444827-29-5
|
100%
|
|
Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for resear...
|
T2869 |
Emodin
|
518-82-1
|
94.4%
|
|
Emodin is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated b...
|
T5188 |
GC376 sodium
|
1416992-39-6
|
96.56%
|
|
GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.
|
T6190 |
Telaprevir
|
402957-28-2
|
96.9%
|
|
Telaprevir (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
|
T1131 |
Ivermectin
|
70288-86-7
|
97.74%
|
|
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
|
T3S0136 |
4'-O-Methylbavachalcone
|
20784-60-5
|
97.85%
|
|
4'-O-Methylbavachalcone is isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) act...
|
T3S1447 |
Arteannuin B
|
50906-56-4
|
98%
|
|
1. Arteannuin B has potent antimalarial activity.
|
T1303 |
Auranofin
|
34031-32-8
|
98%
|
|
Auranofin is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and mornin...
|
T8371 |
ML188
|
1417700-13-0
|
98.04%
|
|
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
|
T9066 |
Merafloxacin
|
91188-00-0
|
98.2%
|
|
Merafloxacin is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.
|
T40660 |
Kansuinine B
|
57685-46-8
|
98.49%
|
|
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research.
|
T1307 |
Carmofur
|
61422-45-5
|
98.59%
|
|
Carmofur is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopat...
|
T8688 |
(Rac)-X77
|
2144491-78-9
|
98.62%
|
|
CPD77 is a potent SARS- CoV- 2 main protease inhibitor.
|
T9287 |
Hydroxychloroquine
|
118-42-3
|
99.03%
|
|
Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a med...
|
T8676 |
FOY 251
|
71079-09-9
|
99.04%
|
|
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
|
TQ0302 |
Thapsigargin
|
67526-95-8
|
99.07%
|
|
Thapsigargin is a microsomal Ca2+-ATPase inhibitor and Endoplasmic Reticulum stress-inducing agent.
|