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SARS-CoV

Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1) is a strain of virus that causes severe acute respiratory syndrome (SARS). It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the ACE2 receptor. It infects humans, bats, and palm civets.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0951 Hydroxychloroquine sulfate 747-36-4 99.87%
Hydroxychloroquine sulfate
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
T0104 Umifenovir hydrochloride 131707-23-8 99.85%
Umifenovir hydrochloride
Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with h...
T7991 2-Hydroxycinnamic acid 614-60-8 99.83%
2-Hydroxycinnamic acid
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.
T9672 GRL-0496 1087243-14-8 99.83%
GRL-0496
GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μ...
T79659 SARS-CoV-2 3CLpro-IN-16 352659-40-6 99.81%
SARS-CoV-2 3CLpro-IN-16
SARS-CoV-2 3CLpro-IN-16 is a covalent SARS-CoV-2 3CLpro inhibitor that inhibits 3CLpro activity and achieves its inhibitory effect by forming a covalent bond wit...
T3S1447 Arteannuin B 50906-56-4 99.8%
Arteannuin B
1. Arteannuin B has potent antimalarial activity.
T6388 Amprenavir 161814-49-9 99.79%
Amprenavir
Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) proteas...
T1803 GNF-5 778277-15-9 99.78%
GNF-5
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic propertie...
T1076 Dexamethasone 50-02-2 99.77%
Dexamethasone
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activit...
T11464 GRL0617 1093070-16-6 99.77%
GRL0617
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
T4686 Simeprevir 923604-59-5 99.77%
Simeprevir
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
T0100L Atazanavir 198904-31-3 99.76%
Atazanavir
Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.
T7222 GS-441524 1191237-69-0 99.73%
GS-441524
GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.
T3319 Scutellarein 529-53-3 99.7%
Scutellarein
Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.
T2391 Camostat mesylate 59721-29-8 99.69%
Camostat mesylate
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
T9341 Bemnifosbuvir 1998705-64-8 99.69%
Bemnifosbuvir
Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.
T0100 Atazanavir sulfate 229975-97-7 99.67%
Atazanavir sulfate
Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with ...
T8309 EIDD-2801 2349386-89-4 99.66%
EIDD-2801
EIDD-2801 (Molnupiravir) is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multi...
T4578 Tipranavir 174484-41-4 99.66%
Tipranavir
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activit...
T0860 Mefloquine hydrochloride 51773-92-3 99.65%
Mefloquine hydrochloride
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
Hydroxychloroquine sulfate
T0951
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
Umifenovir hydrochloride
T0104
Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with h...
2-Hydroxycinnamic acid
T7991
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.
GRL-0496
T9672
GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μ...
SARS-CoV-2 3CLpro-IN-16
T79659
SARS-CoV-2 3CLpro-IN-16 is a covalent SARS-CoV-2 3CLpro inhibitor that inhibits 3CLpro activity and achieves its inhibitory effect by forming a covalent bond wit...
Arteannuin B
T3S1447
1. Arteannuin B has potent antimalarial activity.
Amprenavir
T6388
Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) proteas...
GNF-5
T1803
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic propertie...
Dexamethasone
T1076
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activit...
GRL0617
T11464
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
Simeprevir
T4686
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
Atazanavir
T0100L
Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.
GS-441524
T7222
GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.
Scutellarein
T3319
Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.
Camostat mesylate
T2391
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
Bemnifosbuvir
T9341
Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.
Atazanavir sulfate
T0100
Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with ...
EIDD-2801
T8309
EIDD-2801 (Molnupiravir) is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multi...
Tipranavir
T4578
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activit...
Mefloquine hydrochloride
T0860
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
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TargetMol