T15656 |
KGA-2727
|
666842-36-0
|
98.95%
|
|
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/K...
|
T16083 |
Mizagliflozin
|
666843-10-3
|
98.32%
|
|
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over S...
|
T1782 |
Canagliflozin
|
842133-18-0
|
98.01%
|
|
Canagliflozin (JNJ 28431754AAA), a sodium-glucose transporter 2( SGLT2) and P-Glycoprotein inhibitor, is used in type 2 diabetes.
|
T38843 |
Enavogliflozin
|
1415472-28-4
|
97.81%
|
|
Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.
|
T67849 |
O-Desethyl Dapagliflozin
|
864070-37-1
|
97.09%
|
|
O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.
|
T5016 |
Tofogliflozin (hydrate)
|
1201913-82-7
|
97.02%
|
|
Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human,...
|
T28757 |
Sergliflozin etabonate
|
408504-26-7
|
95.59%
|
|
Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.
|
T7217 |
Bexagliflozin
|
1118567-05-7
|
|
|
Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6 μM and 2 nM for human SGLT1 and SGLT2, r...
|
T2924 |
Phloretin
|
60-82-2
|
98%
|
|
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a ...
|
T68174 |
Sergliflozin A
|
360775-96-8
|
98%
|
|
Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.
|
T15244 |
Ertugliflozin L-pyroglutamic acid
|
1210344-83-4
|
98%
|
|
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-p...
|