T21267 |
HODHBt
|
28230-32-2
|
99.99%
|
|
HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.
|
TN1674 |
Garcinone D
|
107390-08-9
|
99.94%
|
|
Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal a...
|
TN2269 |
Tetramethylcurcumin
|
52328-97-9
|
99.94%
|
|
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also i...
|
T8597 |
ML116
|
744270-00-6
|
99.94%
|
|
ML116 is a potent and selective STAT3 inhibitor.
|
T0433 |
Artesunate
|
88495-63-0
|
99.91%
|
|
Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and m...
|
T2896 |
Alantolactone
|
546-43-0
|
99.91%
|
|
Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing th...
|
T3971 |
CASIN
|
425399-05-9
|
99.86%
|
|
CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
|
T6S1966 |
Curculigoside
|
85643-19-2
|
99.85%
|
|
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulat...
|
T2168 |
2-(1,8-naphthyridin-2-yl)phenol
|
65182-56-1
|
99.84%
|
|
2-NP is a STAT1 enhancer.
|
T0711L |
Niclosamide olamine
|
1420-04-8
|
99.83%
|
|
Niclosamide olamine (Niclosamide Ethanolamine salt) is an Repellent, Insect Attractant and Chemosterilant.
|
T8546 |
BD750
|
892686-59-8
|
99.76%
|
|
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in ...
|
T5S1607 |
Morusin
|
62596-29-6
|
99.72%
|
|
1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuat...
|
T8719 |
SC99
|
882290-02-0
|
99.68%
|
|
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation...
|
T6308 |
Stattic
|
19983-44-9
|
99.64%
|
|
Stattic (STAT3 Inhibitor V) is a small molecule inhibitor of STAT3. It selectively inhibits STAT3 activation, dimerization, and nuclear translocation (IC50: 5.1 ...
|
T2546 |
Pimozide
|
2062-78-4
|
99.63%
|
|
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopamine...
|
T8213 |
Isolinderalactone
|
957-66-4
|
99.62%
|
|
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
|
T15582 |
InS3-54A18
|
328998-53-4
|
99.54%
|
|
inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.
|
T21694 |
(R)-Lisofylline
|
100324-81-0
|
99.50%
|
|
(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated ...
|
T3S1775 |
Tectochrysin
|
520-28-5
|
99.49%
|
|
1. Tectochrysin (Techtochrysine) has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrys...
|
T4S0145 |
Corylifol A
|
775351-88-7
|
99.48%
|
|
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respe...
|