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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T16964 SYM2206 173952-44-8 99.88%
SYM2206
SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated ...
T0943 Carbamazepine 298-46-4 99.88%
Carbamazepine
Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazep...
T0378 Oxybuprocaine hydrochloride 5987-82-6 99.87%
Oxybuprocaine hydrochloride
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.
T0678 Amitriptyline hydrochloride 549-18-8 99.87%
Amitriptyline hydrochloride
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive ...
T27753 KT-362 fumarate 105394-80-7 99.87%
KT-362 fumarate
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
T27830L Lifarizine FA 99.87%
Lifarizine FA
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.
TN6713 6-Benzoylheteratisine 99759-48-5 99.87%
6-Benzoylheteratisine
6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid. It can inhibits voltage-gated Na+ channels...
T9461 AZ194 2241651-99-8 99.86%
AZ194
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
T5333 Rimeporide hydrochloride 187870-95-7 99.84%
Rimeporide hydrochloride
Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
T12608 QX-314 chloride 5369-03-9 99.84%
QX-314 chloride
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
T77693 Nav1.8-IN-4 1620846-16-3 99.83%
Nav1.8-IN-4
Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.
T4008 Metergoline 17692-51-2 99.83%
Metergoline
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
T1053 Mebeverine hydrochloride 2753-45-9 99.83%
Mebeverine hydrochloride
Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut....
T1386 Phenazopyridine hydrochloride 136-40-3 99.83%
Phenazopyridine hydrochloride
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include na...
T1144 Lidocaine hydrochloride 73-78-9 99.83%
Lidocaine hydrochloride
Lidocaine hydrochloride (Lignocaine hydrochloride) is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and...
T0792 (-)-Sparteine sulfate pentahydrate 6160-12-9 99.82%
(-)-Sparteine sulfate pentahydrate
(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium ...
T0349 Riluzole 1744-22-5 99.81%
Riluzole
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMY...
T39630 Zandatrigine 2154406-04-7 99.81%
Zandatrigine
Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy tre...
T16514 PF 04531083 1079400-07-9 99.81%
PF 04531083
PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.
T5324 BI 01383298 2227549-00-8 99.81%
BI 01383298
BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).
SYM2206
T16964
SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated ...
Carbamazepine
T0943
Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazep...
Oxybuprocaine hydrochloride
T0378
Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.
Amitriptyline hydrochloride
T0678
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive ...
KT-362 fumarate
T27753
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by...
Lifarizine FA
T27830L
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.
6-Benzoylheteratisine
TN6713
6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid. It can inhibits voltage-gated Na+ channels...
AZ194
T9461
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
Rimeporide hydrochloride
T5333
Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
QX-314 chloride
T12608
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
Nav1.8-IN-4
T77693
Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.
Metergoline
T4008
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migrain...
Mebeverine hydrochloride
T1053
Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut....
Phenazopyridine hydrochloride
T1386
Phenazopyridine hydrochloride (Pyridium) is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include na...
Lidocaine hydrochloride
T1144
Lidocaine hydrochloride (Lignocaine hydrochloride) is a local anesthetic and cardiac depressant used as an antiarrhythmic agent. Its actions are more intense and...
(-)-Sparteine sulfate pentahydrate
T0792
(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium ...
Riluzole
T0349
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMY...
Zandatrigine
T39630
Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy tre...
PF 04531083
T16514
PF 04531083 is a selective blocker of the NaV1.8 channel. PF 04531083 can be used for neuropathic and inflammatory pain studies.
BI 01383298
T5324
BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).
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TargetMol