T12655 |
(Rac)-AMG8379
|
1641574-26-6
|
99.6%
|
|
(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.
|
T0460 |
Pramocaine hydrochloride
|
637-58-1
|
99.57%
|
|
Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.
|
T0386 |
Ropivacaine hydrochloride
|
98717-15-8
|
99.55%
|
|
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity....
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T6234 |
Ambroxol hydrochloride
|
23828-92-4
|
99.55%
|
|
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is ...
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T22675 |
Co 102862
|
181144-66-1
|
99.54%
|
|
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.
|
T1308 |
Orphenadrine hydrochloride
|
341-69-5
|
99.54%
|
|
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
|
T80626 |
VGSCs-IN-1
|
1204296-79-6
|
99.50%
|
|
VGSCs-IN-1 is a potent VGSC inhibitor, a 2-piperazine analog of Riluzole that exhibits good blocking activity on Nav1.4.VGSCs-IN-1 can be used to study cellular ...
|
T7064 |
Valproic Acid
|
99-66-1
|
99.49%
|
|
Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. C...
|
T1389 |
Dyclonine hydrochloride
|
536-43-6
|
99.49%
|
|
Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .
|
T9647 |
GX 201
|
1788071-27-1
|
99.46%
|
|
GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
|
T0364L |
Dibucaine hydrochloride
|
61-12-1
|
99.45%
|
|
Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.
|
T16897 |
SM-6586
|
103898-38-0
|
99.43%
|
|
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular ...
|
T7502L |
PF 05089771
|
1235403-62-9
|
99.42%
|
|
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that...
|
T0862 |
Diphenidol hydrochloride
|
3254-89-5
|
99.42%
|
|
Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
|
T79835 |
Aneratrigine hydrochloride
|
2097163-75-0
|
99.39%
|
|
Aneratrigine hydrochloride is a sodium channel protein type 9 subunit blocker that may be used for the prevention or treatment of sodium channel blocker-related ...
|
T2342 |
Raxatrigine
|
934240-30-9
|
99.39%
|
|
Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
|
T68599 |
Orphenadrine
|
83-98-7
|
99.38%
|
|
Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner, producin...
|
T8711 |
PF-05186462
|
1235406-03-7
|
99.37%
|
|
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
|
T22361 |
Mepivacaine
|
96-88-8
|
99.35%
|
|
Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by bi...
|
T12181 |
NaV1.7 inhibitor-1
|
1494585-79-3
|
99.35%
|
|
NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).
|