T5S0890 |
Oleandrin
|
465-16-7
|
99.31%
|
|
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcr...
|
T5850 |
Benzamil
|
2898-76-2
|
99.3%
|
|
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
|
TQ0014 |
GNE-131
|
1629063-81-5
|
99.29%
|
|
GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).
|
TP1852L |
Myomodulin acetate(110570-93-9 free base)
|
TP1852L
|
99.24%
|
|
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
|
T15260 |
Evenamide
|
1092977-61-1
|
99.15%
|
|
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
|
T17227 |
Vernakalant Hydrochloride
|
748810-28-8
|
99.04%
|
|
Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.
|
T69795 |
Crobenetine
|
221019-25-6
|
99%
|
|
Crobenetine (BIII 890 CL) Free Base is a selective NaV channel blocker that eliminates VTD-induced [Ca2+] elevation.
|
T15207 |
Eleclazine hydrochloride
|
1448754-43-5
|
98.95%
|
|
Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
|
T21996 |
Zoniporide hydrochloride
|
241800-97-5
|
98.93%
|
|
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride ...
|
T1334 |
Hydroquinidine
|
1435-55-8
|
98.9%
|
|
Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.
|
T1033 |
Monensin sodium salt
|
22373-78-0
|
98.74%
|
|
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the...
|
T3956 |
Sodium ionophore III
|
81686-22-8
|
98.54%
|
|
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
|
T23070 |
Nisoxetine hydrochloride
|
57754-86-6
|
98.52%
|
|
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
|
T3524 |
Halofuginone hydrobromide
|
64924-67-0
|
98.5%
|
|
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
|
T1046 |
Mexiletine hydrochloride
|
5370-01-4
|
98.44%
|
|
Mexiletine hydrochloride (KOE-1173 (hydrochloride)) is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structur...
|
T0468 |
Lidocaine
|
137-58-6
|
98.35%
|
|
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation o...
|
T13428 |
(5R)-BW-4030W92
|
189013-61-4
|
98.27%
|
|
(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer. (5R)-BW-4030W92 is an orally available, non-selective, voltage-dependent and use-dependent so...
|
T6633 |
Ranolazine
|
95635-55-5
|
98.2%
|
|
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium cha...
|
T8444 |
N-Me-aminopyrimidinone9
|
1356834-62-2
|
98.2%
|
|
N-Me-aminopyrimidinone9 is a sodium channel antagonist
|
T4550 |
Ajmaline
|
4360-12-7
|
98.19%
|
|
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or v...
|