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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T5S0890 Oleandrin 465-16-7 99.31%
Oleandrin
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcr...
T5850 Benzamil 2898-76-2 99.3%
Benzamil
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
TQ0014 GNE-131 1629063-81-5 99.29%
GNE-131
GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).
TP1852L Myomodulin acetate(110570-93-9 free base) TP1852L 99.24%
Myomodulin acetate(110570-93-9 free base)
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
T15260 Evenamide 1092977-61-1 99.15%
Evenamide
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
T17227 Vernakalant Hydrochloride 748810-28-8 99.04%
Vernakalant Hydrochloride
Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.
T69795 Crobenetine 221019-25-6 99%
Crobenetine
Crobenetine (BIII 890 CL) Free Base is a selective NaV channel blocker that eliminates VTD-induced [Ca2+] elevation.
T15207 Eleclazine hydrochloride 1448754-43-5 98.95%
Eleclazine hydrochloride
Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
T21996 Zoniporide hydrochloride 241800-97-5 98.93%
Zoniporide hydrochloride
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride ...
T1334 Hydroquinidine 1435-55-8 98.9%
Hydroquinidine
Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.
T1033 Monensin sodium salt 22373-78-0 98.74%
Monensin sodium salt
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the...
T3956 Sodium ionophore III 81686-22-8 98.54%
Sodium ionophore III
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
T23070 Nisoxetine hydrochloride 57754-86-6 98.52%
Nisoxetine hydrochloride
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
T3524 Halofuginone hydrobromide 64924-67-0 98.5%
Halofuginone hydrobromide
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
T1046 Mexiletine hydrochloride 5370-01-4 98.44%
Mexiletine hydrochloride
Mexiletine hydrochloride (KOE-1173 (hydrochloride)) is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structur...
T0468 Lidocaine 137-58-6 98.35%
Lidocaine
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation o...
T13428 (5R)-BW-4030W92 189013-61-4 98.27%
(5R)-BW-4030W92
(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer. (5R)-BW-4030W92 is an orally available, non-selective, voltage-dependent and use-dependent so...
T6633 Ranolazine 95635-55-5 98.2%
Ranolazine
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium cha...
T8444 N-Me-aminopyrimidinone9 1356834-62-2 98.2%
N-Me-aminopyrimidinone9
N-Me-aminopyrimidinone9 is a sodium channel antagonist
T4550 Ajmaline 4360-12-7 98.19%
Ajmaline
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or v...
Oleandrin
T5S0890
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcr...
Benzamil
T5850
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
GNE-131
TQ0014
GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).
Myomodulin acetate(110570-93-9 free base)
TP1852L
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
Evenamide
T15260
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
Vernakalant Hydrochloride
T17227
Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.
Crobenetine
T69795
Crobenetine (BIII 890 CL) Free Base is a selective NaV channel blocker that eliminates VTD-induced [Ca2+] elevation.
Eleclazine hydrochloride
T15207
Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
Zoniporide hydrochloride
T21996
Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride ...
Hydroquinidine
T1334
Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.
Monensin sodium salt
T1033
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the...
Sodium ionophore III
T3956
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
Nisoxetine hydrochloride
T23070
Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitor
Halofuginone hydrobromide
T3524
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
Mexiletine hydrochloride
T1046
Mexiletine hydrochloride (KOE-1173 (hydrochloride)) is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structur...
Lidocaine
T0468
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation o...
(5R)-BW-4030W92
T13428
(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer. (5R)-BW-4030W92 is an orally available, non-selective, voltage-dependent and use-dependent so...
Ranolazine
T6633
Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium cha...
N-Me-aminopyrimidinone9
T8444
N-Me-aminopyrimidinone9 is a sodium channel antagonist
Ajmaline
T4550
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or v...
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TargetMol