T9017 |
HPK1-IN-2
|
2056122-11-1
|
99.62%
|
|
HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) is a potent and orally active inhibitor of hema...
|
T22306 |
DGY-06-116
|
T22306
|
99.6%
|
|
DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.
|
T6227 |
Benidipine hydrochloride
|
91599-74-5
|
99.56%
|
|
Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.
|
T9002 |
SquarunkinA
|
2101958-02-3
|
99.52%
|
|
squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-t...
|
T4597 |
UM-164
|
903564-48-7
|
99.52%
|
|
UM-164 (DAS-DFGO-II) is a highly potent inhibitor of c-Src with a Kd of 2.7 nM. UM-164 also potently inhibits p38α and p38β.
|
TQ0132 |
A 419259 trihydrochloride
|
1435934-25-0
|
99.47%
|
|
A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).
|
T1812 |
KX1-004
|
518058-84-9
|
99.42%
|
|
KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.
|
T15675 |
Tirbanibulin Mesylate
|
1080645-95-9
|
99.42%
|
|
Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
|
T11916 |
Lyn-IN-1
|
887650-05-7
|
99.33%
|
|
Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and Lyn
|
T1754 |
ZM 306416
|
690206-97-4
|
99.31%
|
|
ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
|
T3063 |
PD173955
|
260415-63-2
|
99.28%
|
|
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and PKC...
|
T16760 |
RK-24466
|
213743-31-8
|
99.26%
|
|
RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.
|
T23127 |
PD-161570
|
192705-80-9
|
99.23%
|
|
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c...
|
T8995 |
NCGC00262650
|
344359-25-7
|
99.23%
|
|
NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
|
T2070 |
Agerafenib
|
1188910-76-0
|
99.23%
|
|
Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.
|
T6920 |
ON123300
|
1357470-29-1
|
99.22%
|
|
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
|
T13824 |
PP58
|
212391-58-7
|
99.21%
|
|
PP58 is an inhibitor of PDGFR, FGFR and Src family.
|
T2153 |
1-NM-PP1
|
221244-14-0
|
99.2%
|
|
1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
|
T6419 |
BMS-536924
|
468740-43-4
|
99.19%
|
|
BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for ...
|
T2415 |
PP121
|
1092788-83-4
|
99.19%
|
|
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , ...
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