Src

Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck, Blk, and Lyn in the SrcB subfamily, and Frk in its own subfamily. Frk has homologs in invertebrates such as flies and worms, and Src homologs exist in organisms as diverse as unicellular choanoflagellates, but the SrcA and SrcB subfamilies are specific to vertebrates. Src family kinases contain six conserved domains: a N-terminal myristoylated segment, a SH2 domain, a SH3 domain, a linker region, a tyrosine kinase domain, and C-terminal tail.

Cat. No.	Product name	CAS No.	Purity
T8995	NCGC00262650	344359-25-7	99.23%
T8995	NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
T2070	Agerafenib	1188910-76-0	99.23%
T2070	Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.
T13824	PP58	212391-58-7	99.21%
T13824	PP58 is an inhibitor of PDGFR, FGFR and Src family.
T2153	1-NM-PP1	221244-14-0	99.2%
T2153	1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
T6419	BMS-536924	468740-43-4	99.19%
T6419	BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for ...
T2415	PP121	1092788-83-4	99.19%
T2415	PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , ...
T1985	WHI-P154	211555-04-3	99.19%
T1985	WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
T6077	ZM-447439	331771-20-1	99.11%
T6077	ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective f...
T6315	MLN8054	869363-13-3	99.05%
T6315	MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.
T6732	WYE-687	1062161-90-3	98.98%
T6732	WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(...
T17267	XL228	898280-07-4	98.92%
T17267	XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).
T23176	PP 3	5334-30-5	98.92%
T23176	PP 3 is a Negative control for the Src kinase inhibitor PP 2
T78605	CpCDPK1/TgCDPK1-IN-1	1092788-23-2	98.71%
T78605	CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infectio...
T6982	SGI-7079	1239875-86-5	98.7%
T6982	SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR...
T37603L	Osteogenic Growth Peptide (10-14) acetate		98.69%
T37603L	Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesi...
T9411	KX2-361	897016-26-1	98.52%
T9411	KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
T23128	PD180970	287204-45-9	98.47%
T23128	PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies...
T6594	MNS	1485-00-3	98.45%
T6594	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T2327	Pelitinib	257933-82-7	98.37%
T2327	Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).
T6350	CHIR-124	405168-58-3	98.35%
T6350	CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.