TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.

Cat. No.	Product name	CAS No.	Purity
T10929L	D-3263 hydrochloride	1008763-54-9	99.85%
T10929L	D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
T2170	SKF-96365 hydrochloride	130495-35-1	99.85%
T2170	SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells...
T2994	(E)-Cardamonin	19309-14-9	99.84%
T2994	(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel...
T8607	M084	51314-51-3	99.84%
T8607	M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.
T16483	PF-05105679	1398583-31-7	99.82%
T16483	PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.
T6646	Rosiglitazone hydrochloride	302543-62-0	99.79%
T6646	Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
T3727	Methyl syringate	884-35-5	99.76%
T3727	Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with a different mode of action from that of gallic ac...
T10537	BI-749327	2361241-23-6	99.74%
T10537	BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).
T12306	OMDM-5	616884-66-3	99.72%
T12306	OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
T29522	ABT 102	808756-71-0	99.72%
T29522	ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.
T8442	M8-B Hydrochloride	883976-12-3	99.71%
T8442	M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
T7416	WS-12	68489-09-8	99.71%
T7416	WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)
T29968	AMG-0347	946615-43-6	99.7%
T29968	AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neuron...
T16686	Pyr10	1315323-00-2	99.7%
T16686	Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal in...
T4680L	HC067047 Hydrochloride(883031-03-6 free base)	1481646-76-7	99.68%
T4680L	HC-067047 hydrochloride is a potent and selective TRPV4 antagonist. HC-067047 hydrochloride reversibly inhibited currents through the human, rat, and mouse TRPV4...
T12514	Podocarpic acid	5947-49-9	99.67%
T12514	Podocarpic acid is a natural product and a novel TRPA1 activator.
T1109	(Z)-Capsaicin	25775-90-0	99.67%
T1109	(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of natur...
T6379	AMG 517	659730-32-2	99.66%
T6379	AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1...
T9263	Cim0216	1031496-06-6	99.6%
T9263	CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
T2952	Camphor	76-22-2	99.53%
T2952	Camphor (2-Camphanone) is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and a...