TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.

Cat. No.	Product name	CAS No.	Purity
T9245	TRPM4-IN-1	351424-20-9	98.75%
T9245	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
T17006	TC-I 2014	1221349-53-6	98.75%
T17006	TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin...
TCS0102	Pulegone	89-82-7	98.74%
TCS0102	1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pule...
T22537	9-Phenanthrol	484-17-3	98.72%
T22537	9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
T16532	Pico145	1628287-16-0	98.71%
T16532	Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits ( )-englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cell...
T8307	Hydroxy-α-sanshool	83883-10-7	98.59%
T8307	Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).
T23322	SB 452533	459429-39-1	98.52%
T23322	SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).
T15628	JT010	917562-33-5	98.5%
T15628	JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
T41233	Cis-22a	1819366-84-1	98.49%
T41233	Cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative ...
T4385	PF-4840154	1332708-14-1	98.48%
T4385	PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 2...
T37097	SET 2	2313525-20-9	98.43%
T37097	SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.
T8440	LASSBio-1135	852453-71-5	98.43%
T8440	LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.
T4693	2-Aminoethyl diphenylborinate	524-95-8	98.43%
T4693	2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at high...
T8528	AC1903	831234-13-0	98.33%
T8528	AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.
T1062	Capsaicin	404-86-4	98.28%
T1062	Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory,...
T23107	Ononetin	487-49-0	98.15%
T23107	Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).
T8410	ASP7663	1190217-35-6	98.11%
T8410	ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.
T33429	MK-2295	878811-00-8	98.1%
T33429	MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment of chronic pain.
T2845	Imperatorin	482-44-0	98.07%
T2845	Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and m...
T77511	TRPA1-IN-2	2415206-22-1	98.05%
T77511	TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.