TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.

Cat. No.	Product name	CAS No.	Purity
T24477	MK6-83	1062271-24-2	98%
T24477	MK6-83 is the transient receptor potential channel ML3 agonist.
T77723	RN-1665	1803003-65-7	98%
T77723	RN-1665 is a potent and selective TRPV4 receptor antagonist.
T21543	AP 18	55224-94-7	98%
T21543	AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human a...
T9818	NGD-8243	573678-04-3	98%
T9818	NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention and...
T37428	TRPC6-PAM-C20	667427-75-0	98%
T37428	TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 wi...
T1062	Capsaicin	404-86-4	98%
T1062	Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory,...
T10300	AMG2850	1470018-52-0	98%
T10300	AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
T40042	Evifacotrep	2413739-88-3	98%
T40042	Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100). Evifacotrep can be used for the research of neur...
TQ0157	EIPA	1154-25-2	98%
TQ0157	EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
TN1927	Methyl Kakuol	70342-29-9	98%
TN1927	Methyl Kakuol is an agonist of TRPA1 with an EC50 of 0.27 µM and can be used in studies about acting as an active ingredient in MBST constituent Asiasari Radix.
T4680	HC-067047	883031-03-6	98%
T4680	HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
T8562	A 425619	581809-67-8	98%
T8562	A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist
T2007	RQ-00203078	1254205-52-1	98%
T2007	RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
T6977	SB-366791	472981-92-3	98%
T6977	SB-366791 is a new and selective cinnamide TRPV1 antagonist.
TN1377	α-Spinasterol	481-18-5	98%
TN1377	α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α...
T12849	SAR7334	1333210-07-3	98%
T12849	SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
T7572	RN-1734	946387-07-1	98%
T7572	RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)
T1622	Rosiglitazone maleate	155141-29-0	98%
T1622	Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplas...
T77645	JC-229		98%
T77645	JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
T7177	Capsazepine	138977-28-3	98%
T7177	Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of c...