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Search Results for " tsh receptor "

Targets

8

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1022 Protirelin Acetate TSH-RF Acetate,TRH Acetate,TRF Acetate Thyroid hormone receptor(THR) , Endogenous Metabolite
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
T12073 ML-109 TSH Receptor
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)
T12192 NCGC00229600 Others , TSH Receptor
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
T5383 D3-βArr NCGC00379308 TSH Receptor
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
T7618 Pyributicarb TSH-888 P450
Pyributicarb (TSH-888) is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR).
T76727 Teprotumumab R 1507,HZN 001 TSH Receptor , IGF-1R
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te...
T24502 MS437 MS 437,MS-437
MS437 is a potent TSH receptor agonist.
T24503 MS438 MS-438,MS 438
MS438 is an effective agonist of the TSH receptor.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04853 TSHR Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre...
TMPY-03784 GPHA2 Protein, Human, Recombinant (His) Human HEK293
GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The a...
TMPY-03812 GPHA2 Protein, Human, Recombinant (mFc) Human HEK293
GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The a...
TMPY-06821 THRB Protein, Human, Recombinant (His) Human E. coli
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
TargetMol