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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1022 | Protirelin Acetate | TSH-RF Acetate,TRH Acetate,TRF Acetate | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary. | |||
T12073 | ML-109 | TSH Receptor | |
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM) | |||
T12192 | NCGC00229600 | Others , TSH Receptor | |
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies. | |||
T5383 | D3-βArr | NCGC00379308 | TSH Receptor |
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. | |||
T7618 | Pyributicarb | TSH-888 | P450 |
Pyributicarb (TSH-888) is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR). | |||
T76727 | Teprotumumab | R 1507,HZN 001 | TSH Receptor , IGF-1R |
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te... | |||
T24502 | MS437 | MS 437,MS-437 | |
MS437 is a potent TSH receptor agonist. | |||
T24503 | MS438 | MS-438,MS 438 | |
MS438 is an effective agonist of the TSH receptor. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04853 | TSHR Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre... | |||
TMPY-03784 | GPHA2 Protein, Human, Recombinant (His) | Human | HEK293 |
GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The a... | |||
TMPY-03812 | GPHA2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The a... | |||
TMPY-06821 | THRB Protein, Human, Recombinant (His) | Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin... |