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Search Result

Search Results for " thyroid-hormone-receptor(thr) "

Targets

Thyroid hormone receptor(THR)

15

Compounds

4

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T40548 NH-3 Thyroid hormone receptor(THR)
NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...
T5360 Eprotirome KB2115 Thyroid hormone receptor(THR)
Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
T1604 Tiratricol 3,3',5-Triiodothyroacetic acid Thyroid hormone receptor(THR)
Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A...
T13072 Taltirelin acetate TA-0910 acetate Thyroid hormone receptor(THR)
Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).
T3595 Resmetirom VIA-3196,MGL3196 Thyroid hormone receptor(THR)
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.
T5313 Sobetirome IACS-010759,QRX-431 Thyroid hormone receptor(THR)
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T13492 3,5-Diiodothyropropionic acid C082182,Ditpa cpd Thyroid hormone receptor(THR)
3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).
T7578 REVERSE T3 3,3',5'-triiodo-L-thyronine Thyroid hormone receptor(THR)
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
TP1022 Protirelin Acetate TSH-RF Acetate,TRH Acetate,TRF Acetate Thyroid hormone receptor(THR) , Endogenous Metabolite
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
T1669 Liothyronine sodium 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel Thyroid hormone receptor(THR)
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine s...
T22355 L-Thyroxine sodium LT4 sodium,Levothyroxine sodium,L-T4 sodium Thyroid hormone receptor(THR)
L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.
T7590 Taltirelin TA-0910 Thyroid hormone receptor(THR)
Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].
T15699 L-Thyroxine sodium salt pentahydrate Sodium levothyroxine pentahydrate,Levothyroxine Thyroid hormone receptor(THR)
L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxi...
T79089 THR-β modulator-1
THR-β Modulator-1 (Compound 1a) is a potent modulator of the thyroid hormone receptor β, utilized in the study of thyroid hormone receptor-associated disorders [1].
T74785 THR-β agonist 6
THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remar...
Cat No. Product Name Synonyms Targets
T6956 Protirelin Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF Thyroid hormone receptor(THR) , Endogenous Metabolite
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
T0864 L-Thyroxine Levothyroxine,NSC 36397,T4 Thyroid hormone receptor(THR) , Endogenous Metabolite
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in...
T1653 Liothyronine Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine Thyroid hormone receptor(THR) , Endogenous Metabolite
Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
T16442 PCO371 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- Thyroid hormone receptor(THR)
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...

Natural Products

Protirelin
T6956
Synonym: Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
L-Thyroxine
T0864
Synonym: Levothyroxine,NSC 36397,T4
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
Liothyronine
T1653
Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
PCO371
T16442
Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-
Target: Thyroid hormone receptor(THR)

Recombinant Proteins

Species：
Human (1)
Expression System：
E. coli (1)
Tag：
His (1)
Cat No. Product Name Species Expression System
TMPY-06821 THRB Protein, Human, Recombinant (His) Human E. coli
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
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