Thyroid hormone receptor(THR)|Targetmol

Thyroid hormone receptor(THR)

The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone.TRs act as transcription factors, ultimately affecting the regulation of gene transcription and translation. These receptors also have non-genomic effects that lead to second messenger activation, and corresponding cellular response.

Cat No.	Product Name
T0840	Methimazole	Methimazole is a thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl res...
T0864	L-Thyroxine	Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling ...
T0952	Carbimazole	Carbimazole is an imidazole antithyroid agent. It is only found in individuals that have used or taken this drug. Carbimazole is metabolized to methimazole, whi...
T1309	Propylthiouracil	Propylthiouracil is a thiourea derivative with an antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction w...
T1310	Deracil	Deracil is a thiolated uracil derivative that is a known anti-hyperthyroid agent.
T1604	Tiratricol	Tiratricol is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials ...
T1653	Lyothyronine	Liothyronine is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
T1669	Liothyronine sodium	Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyro...
T3595	MGL3196	MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist.
T5313	Sobetirome	Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T5360	Eprotirome	Eprotirome, a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
T7578	reverse T3	reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
T15644	KAT681	KAT681 is a liver selective thyromimetic.
T15699	L-Thyroxine sodium salt pentahydrate	DIO enzymes convert biologically active thyroid hormone from L-Thyroxine (T4). L-Thyroxine sodium salt pentahydrate is a synthetic hormone in the treatment of h...
T10855	CO23	CO23 is a selective agonist of the thyroid hormone receptor (TR) α and can be transported through the blood-brain barrier. CO23 is used for growth and developm...
T13072	Taltirelin acetate	Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic...

Cat No.

Product Name

T0840

Methimazole

Methimazole is a thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl res...

T0864

L-Thyroxine

Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling ...

T0952

Carbimazole

Carbimazole is an imidazole antithyroid agent. It is only found in individuals that have used or taken this drug. Carbimazole is metabolized to methimazole, whi...

T1309

Propylthiouracil

Propylthiouracil is a thiourea derivative with an antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction w...

T1310

Deracil

Deracil is a thiolated uracil derivative that is a known anti-hyperthyroid agent.

T1604

Tiratricol

Tiratricol is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials ...

T1653

Lyothyronine

Liothyronine is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.

T1669

Liothyronine sodium

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyro...

T3595

MGL3196

MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist.

T5313

Sobetirome

Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).

T5360

Eprotirome

Eprotirome, a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.

T7578

reverse T3

reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

T15644

KAT681

KAT681 is a liver selective thyromimetic.

T15699

L-Thyroxine sodium salt pentahydrate

DIO enzymes convert biologically active thyroid hormone from L-Thyroxine (T4). L-Thyroxine sodium salt pentahydrate is a synthetic hormone in the treatment of h...

T10855

CO23

CO23 is a selective agonist of the thyroid hormone receptor (TR) α and can be transported through the blood-brain barrier. CO23 is used for growth and developm...

T13072

Taltirelin acetate

Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic...