T11599 |
Ibiglustat (L-Malic acid)
|
1629063-78-0
|
99.79%
|
|
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic a...
|
T6373 |
Alendronate sodium hydrate
|
121268-17-5
|
99.78%
|
|
Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment...
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T9186 |
Ervogastat
|
2186700-33-2
|
99.77%
|
|
Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor. Ervogastat reduces steatosis and hepatic triglyceride levels ...
|
T24030 |
Entacapone acid
|
160391-70-8
|
99.76%
|
|
Entacapone acid (AG 1290) is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).
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T3663 |
Eliglustat
|
491833-29-5
|
99.71%
|
|
Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.
|
T22128 |
OU749
|
519170-13-9
|
99.7%
|
|
OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.
|
TQ0165 |
Arglabin
|
84692-91-1
|
99.62%
|
|
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.
|
TQ0155 |
Miglustat hydrochloride
|
210110-90-0
|
99.61%
|
|
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher dis...
|
T1041 |
Risedronate Sodium
|
115436-72-1
|
99.57%
|
|
Risedronate Sodium (NE 58095 Sodium) is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used...
|
T2644 |
(E)-Daporinad
|
658084-64-1
|
99.44%
|
|
(E)-Daporinad (FK866) is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activi...
|
T27773L |
L-739750 2HCl
|
|
99.34%
|
|
L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.
|
TN6512 |
Tectol
|
24449-39-6
|
99.23%
|
|
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemi...
|
T6271 |
Tipifarnib
|
192185-72-1
|
99.22%
|
|
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein tr...
|
T77633 |
G43
|
690693-02-8
|
99.21%
|
|
G43 is a potent and selective glucosyltransferase inhibitor that inhibits GtfB and GtfC with Kd values of 3.7 μM and 46.9 nM, respectively.G43 exhibits in vitro ...
|
T2678 |
LB42708
|
226929-39-1
|
99.06%
|
|
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
|
T17102 |
Tipifarnib (S enantiomer)
|
192185-71-0
|
99.05%
|
|
Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).
|
TN7057 |
Rosmarinate acid
|
537-15-5
|
99.00%
|
|
Rosmarinate acid(Rosemary acid) inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively
|
T7831 |
Nitecapone
|
116313-94-1
|
99%
|
|
Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)
|
T2216 |
Entacapone
|
130929-57-6
|
98.88%
|
|
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
|
T3182 |
L-778123 hydrochloride
|
253863-00-2
|
98.51%
|
|
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
|