T2700 |
FTI-277 hydrochloride
|
180977-34-8
|
98.19%
|
|
FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than th...
|
T1599L |
Ibandronate sodium
|
138844-81-2
|
98.13%
|
|
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
|
T7439 |
3-Methoxybenzamide
|
5813-86-5
|
98%
|
|
3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
|
T8489 |
Minodronic acid monohydrate
|
155648-60-5
|
98%
|
|
Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
|
T4473 |
Ibiglustat
|
1401090-53-6
|
97.97%
|
|
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation o...
|
T2678 |
LB42708
|
226929-39-1
|
97.83%
|
|
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
|
T1455 |
Nialamide
|
51-12-7
|
90.30%
|
|
Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
|
T16398 |
Opicapone
|
923287-50-7
|
100%
|
|
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for ...
|
T2216 |
Entacapone
|
130929-57-6
|
100%
|
|
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
|
T0525 |
Flopropione
|
2295-58-1
|
100%
|
|
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
|
T25210 |
CBHcy
|
88096-02-0
|
100%
|
|
CBHcy is a dual-substrate analogue, a specific BHMT inhibitor that causes betaine-homocysteine S-methyltransferase (BHMT) to adopt the same conformation as the t...
|
T35626 |
AMP-Deoxynojirimycin
|
216758-20-2
|
98%
|
|
AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2.AMP-Deoxynojirimycin is a potent inhibitor of GlcCer biosynthesi...
|
T6365 |
A 922500
|
959122-11-3
|
98%
|
|
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferas...
|
T6302 |
Lonafarnib
|
193275-84-2
|
98%
|
|
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
|
T11282 |
FGTI-2734
|
1247018-19-4
|
98%
|
|
FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. FGTI-2734...
|
T10512 |
Prenyl-IN-1
|
360561-53-1
|
98%
|
|
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects i...
|
T4681 |
T863
|
701232-20-4
|
98%
|
|
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
|
TN6512 |
Tectol
|
24449-39-6
|
98%
|
|
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemi...
|
T6844 |
GGTI298 Trifluoroacetate
|
1217457-86-7
|
98%
|
|
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycl...
|
T15109 |
DGAT1-IN-1
|
1449779-49-0
|
98%
|
|
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
|