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Transferase

A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of life's most important processes.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2700 FTI-277 hydrochloride 180977-34-8 98.19%
FTI-277 hydrochloride
FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than th...
T1599L Ibandronate sodium 138844-81-2 98.13%
Ibandronate sodium
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
T7439 3-Methoxybenzamide 5813-86-5 98%
3-Methoxybenzamide
3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
T8489 Minodronic acid monohydrate 155648-60-5 98%
Minodronic acid monohydrate
Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
T4473 Ibiglustat 1401090-53-6 97.97%
Ibiglustat
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation o...
T2678 LB42708 226929-39-1 97.83%
LB42708
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
T1455 Nialamide 51-12-7 90.30%
Nialamide
Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
T16398 Opicapone 923287-50-7 100%
Opicapone
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for ...
T2216 Entacapone 130929-57-6 100%
Entacapone
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
T0525 Flopropione 2295-58-1 100%
Flopropione
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
T25210 CBHcy 88096-02-0 100%
CBHcy
CBHcy is a dual-substrate analogue, a specific BHMT inhibitor that causes betaine-homocysteine S-methyltransferase (BHMT) to adopt the same conformation as the t...
T35626 AMP-Deoxynojirimycin 216758-20-2 98%
AMP-Deoxynojirimycin
AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2.AMP-Deoxynojirimycin is a potent inhibitor of GlcCer biosynthesi...
T6365 A 922500 959122-11-3 98%
A 922500
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferas...
T6302 Lonafarnib 193275-84-2 98%
Lonafarnib
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
T11282 FGTI-2734 1247018-19-4 98%
FGTI-2734
FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. FGTI-2734...
T10512 Prenyl-IN-1 360561-53-1 98%
Prenyl-IN-1
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects i...
T4681 T863 701232-20-4 98%
T863
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
TN6512 Tectol 24449-39-6 98%
Tectol
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemi...
T6844 GGTI298 Trifluoroacetate 1217457-86-7 98%
GGTI298 Trifluoroacetate
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycl...
T15109 DGAT1-IN-1 1449779-49-0 98%
DGAT1-IN-1
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
FTI-277 hydrochloride
T2700
FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than th...
Ibandronate sodium
T1599L
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
3-Methoxybenzamide
T7439
3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
Minodronic acid monohydrate
T8489
Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
Ibiglustat
T4473
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation o...
LB42708
T2678
LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).
Nialamide
T1455
Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
Opicapone
T16398
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for ...
Entacapone
T2216
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
Flopropione
T0525
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
CBHcy
T25210
CBHcy is a dual-substrate analogue, a specific BHMT inhibitor that causes betaine-homocysteine S-methyltransferase (BHMT) to adopt the same conformation as the t...
AMP-Deoxynojirimycin
T35626
AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2.AMP-Deoxynojirimycin is a potent inhibitor of GlcCer biosynthesi...
A 922500
T6365
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferas...
Lonafarnib
T6302
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
FGTI-2734
T11282
FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. FGTI-2734...
Prenyl-IN-1
T10512
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects i...
T863
T4681
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
Tectol
TN6512
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemi...
GGTI298 Trifluoroacetate
T6844
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycl...
DGAT1-IN-1
T15109
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
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TargetMol