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VEGFR

VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T14677 BMS-690514 859853-30-8 98%
BMS-690514
BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
T78253 Faricimab 1607793-29-2 98%
Faricimab
Faricimab, a bispecific antibody, simultaneously targets angiopoietin-2 and vascular endothelial growth factor-A (VEGF-A), and is utilized in research on diabeti...
T78759 VEGFR2-IN-4 98%
VEGFR2-IN-4
VEGFR2-IN-4 (compound 25) is a potent, selective inhibitor of the VEGFR2 kinase, exhibiting a GI50 of 0.7 nM and demonstrating anti-angiogenic effects. It is uti...
T78792 Multi-kinase-IN-4 98%
Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.18...
T78819 VEGFR-2-IN-33 98%
VEGFR-2-IN-33
VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving ...
T78845 FGFR1/VEGFR2-IN-1 98%
FGFR1/VEGFR2-IN-1
FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].
T79009 VEGFR2-IN-3 417717-09-0 98%
VEGFR2-IN-3
VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].
T79400 VEGFR-2-IN-35 98%
VEGFR-2-IN-35
VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM. Additionally, it demonstrates inhibitory activity against MCF-7 and HCT...
T79403 VEGFR-2-IN-36 98%
VEGFR-2-IN-36
VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated antica...
T79494 VEGFR-2-IN-31 98%
VEGFR-2-IN-31
VEGFR-2-IN-31 (compound 3i), a robust VEGFR-2 inhibitor (IC50=8.93 nM), serves as an anti-prostate cancer agent by arresting the cell cycle at the S-phase and in...
T79495 VEGFR-2-IN-32 98%
VEGFR-2-IN-32
VEGFR-2-IN-32 (Comp 3a) is an inhibitor of VEGFR-2, exhibiting an inhibitory concentration (IC 50) of 8.93 nM, and demonstrates cytotoxic activity towards PC-3 c...
T79587 HCA/VEGFR-2-IN-2 98%
hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and t...
T79588 HCA/VEGFR-2-IN-3 98%
hCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. This compound ...
T79591 HCA/VEGFR-2-IN-4 98%
hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/X...
T80152 Protein LMWP 121052-30-0 98%
Protein LMWP
Protein LMWP, a cell-penetrating peptide, exhibits inhibitory activity against vascular endothelial growth factor (VEGF), and is utilized in cancer research for ...
T80287 KLTWQELYQLKYKGI 917760-16-8 98%
KLTWQELYQLKYKGI
KLTWQELYQLKYKGI (QK) is a VEGF-mimicking peptide that competes with VEGF by binding to its receptors. It facilitates the healing of gastric ulcers in rodents thr...
T80579 Suvemcitug 1610010-57-5 98%
Suvemcitug
Suvemcitug, an IgG1κ antibody, specifically targets vascular endothelial growth factor (VEGF) and is derived from the African hare (Oryctolagus cuniculus) [1].
T80593 Brolucizumab 1531589-13-5 98%
Brolucizumab
Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment exhibiting low picomolar affinity (K D = 1.05 pM), utilized for cancer research [1] [2].
T80595 Conbercept 1227158-72-6 98%
Conbercept
Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDR, ...
T80872 VEGFR-2-IN-37 298207-77-9 98%
VEGFR-2-IN-37
VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM. It is also identified as a p...
BMS-690514
T14677
BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.
Faricimab
T78253
Faricimab, a bispecific antibody, simultaneously targets angiopoietin-2 and vascular endothelial growth factor-A (VEGF-A), and is utilized in research on diabeti...
VEGFR2-IN-4
T78759
VEGFR2-IN-4 (compound 25) is a potent, selective inhibitor of the VEGFR2 kinase, exhibiting a GI50 of 0.7 nM and demonstrating anti-angiogenic effects. It is uti...
Multi-kinase-IN-4
T78792
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.18...
VEGFR-2-IN-33
T78819
VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving ...
FGFR1/VEGFR2-IN-1
T78845
FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].
VEGFR2-IN-3
T79009
VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].
VEGFR-2-IN-35
T79400
VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM. Additionally, it demonstrates inhibitory activity against MCF-7 and HCT...
VEGFR-2-IN-36
T79403
VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated antica...
VEGFR-2-IN-31
T79494
VEGFR-2-IN-31 (compound 3i), a robust VEGFR-2 inhibitor (IC50=8.93 nM), serves as an anti-prostate cancer agent by arresting the cell cycle at the S-phase and in...
VEGFR-2-IN-32
T79495
VEGFR-2-IN-32 (Comp 3a) is an inhibitor of VEGFR-2, exhibiting an inhibitory concentration (IC 50) of 8.93 nM, and demonstrates cytotoxic activity towards PC-3 c...
hCA/VEGFR-2-IN-2
T79587
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and t...
hCA/VEGFR-2-IN-3
T79588
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. This compound ...
hCA/VEGFR-2-IN-4
T79591
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/X...
Protein LMWP
T80152
Protein LMWP, a cell-penetrating peptide, exhibits inhibitory activity against vascular endothelial growth factor (VEGF), and is utilized in cancer research for ...
KLTWQELYQLKYKGI
T80287
KLTWQELYQLKYKGI (QK) is a VEGF-mimicking peptide that competes with VEGF by binding to its receptors. It facilitates the healing of gastric ulcers in rodents thr...
Suvemcitug
T80579
Suvemcitug, an IgG1κ antibody, specifically targets vascular endothelial growth factor (VEGF) and is derived from the African hare (Oryctolagus cuniculus) [1].
Brolucizumab
T80593
Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment exhibiting low picomolar affinity (K D = 1.05 pM), utilized for cancer research [1] [2].
Conbercept
T80595
Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDR, ...
VEGFR-2-IN-37
T80872
VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM. It is also identified as a p...
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