T10123 |
VEGFR-2-IN-9
|
408502-06-7
|
97.19%
|
|
VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.
|
T13178 |
Toceranib
|
356068-94-5
|
97.14%
|
|
Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 a...
|
T29797 |
AKB-6899
|
1007377-55-0
|
97.11%
|
|
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macr...
|
T5164 |
Cabozantinib hydrochloride
|
1817759-42-4
|
97.09%
|
|
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM...
|
T6458 |
CYC-116
|
693228-63-6
|
96.6%
|
|
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active a...
|
T35570 |
Chiauranib
|
1256349-48-0
|
96.25%
|
|
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related k...
|
T15185 |
Lucitanib
|
1058137-23-7
|
96.13%
|
|
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, ...
|
T2056 |
VEGFR-2-IN-5
|
1430089-64-7
|
81.14%
|
|
VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
|
T6184 |
Orantinib
|
252916-29-3
|
100%
|
|
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It ...
|
T8402 |
Regorafenib Hydrochloride
|
835621-07-3
|
100%
|
|
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with pote...
|
T23554 |
(Z)-FeCP-oxindole
|
1137967-28-2
|
100%
|
|
(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.
|
T6720 |
Vatalanib dihydrochloride
|
212141-51-0
|
100%
|
|
Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against...
|
T22432 |
SU5208
|
62540-08-3
|
100%
|
|
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).
|
T60094 |
SU 4981
|
186610-88-8
|
100%
|
|
SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.
|
T2372L |
Ponatinib Hydrochloride
|
1114544-31-8
|
100%
|
|
Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.3...
|
T7104 |
Dovitinib lactate
|
692737-80-7
|
100%
|
|
Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).
|
T0342 |
Carvedilol phosphate hemihydrate
|
610309-89-2
|
100%
|
|
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
|
T13157 |
TG 100801
|
867331-82-6
|
100%
|
|
TG 100801 is a dual inhibitor of VEGFr2 and Src family (Src and YES) kinases and is a candidate compound for the treatment of age-related macular degeneration (A...
|
TQ0317 |
R1530
|
882531-87-5
|
|
|
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
|
T14943 |
CGP60474
|
164658-13-3
|
|
|
CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits ...
|