T80873 |
VEGFR2/HDAC1-IN-1
|
|
98%
|
|
VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC. It arrests the c...
|
T80874 |
VEGFR-2/c-Met-IN-1
|
|
98%
|
|
VEGFR-2/c-Met-IN-1 is a dual inhibitor targeting VEGFR-2 and c-Met with respective IC50 values of 138 nM and 74 nM, demonstrating antitumor activity [1].
|
T81054 |
T-1-MCPAB
|
|
98%
|
|
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 µM, effectively suppresses MCF7 cell migration and has applications in cancer research [1].
|
T81125 |
Sotiburafusp alfa
|
2637466-37-4
|
98%
|
|
Sotiburafusp alfa is a humanized bispecific fusion protein comprising a VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) connected ...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
T13156 |
TG 100572
|
867334-05-2
|
98%
|
|
TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 ...
|
TN1867 |
Licoricidin
|
30508-27-1
|
98%
|
|
Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
|
TQ0080 |
SU14813 maleate
|
849643-15-8
|
98%
|
|
SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).
|
TN4913 |
Riddelline
|
23246-96-0
|
98%
|
|
Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
|
T6936 |
PF-03814735
|
942487-16-3
|
98%
|
|
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and...
|
TN1095 |
Ginsenoside Rk2
|
364779-14-6
|
98%
|
|
Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities.
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
TN4748 |
Penduletin
|
569-80-2
|
98%
|
|
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
|
TN4603 |
Myricanol
|
33606-81-4
|
98%
|
|
Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.
|
T74000 |
CP-547632 TFA
|
2805804-54-8
|
98%
|
|
CP-547632 TFA is an orally active, ATP-competitive inhibitor that potently targets VEGFR-2 and FGF kinases with IC50 values of 11 nM and 9 nM, respectively. It d...
|
T13157L |
TG 100801 Hydrochloride
|
1018069-81-2
|
98%
|
|
TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase(IC50s of 2, 7, 2, 16, 13, 5, 0....
|
TN5250 |
Vomifoliol
|
23526-45-6
|
98%
|
|
Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major ...
|
T13039 |
Sunitinib-d10
|
1126721-82-1
|
98%
|
|
Sunitinib D10 is a deuterium labeled Sunitinib. Sunitinib is a inhibitor of multi-targeted receptor tyrosine kinase(IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ...
|
TN5050 |
Sprengerinin C
|
88861-91-0
|
98%
|
|
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
|
TN5100 |
Taspine
|
602-07-3
|
98%
|
|
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
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