VEGFR

VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.

Cat. No.	Product name	CAS No.	Purity
T0263	Chloropyramine hydrochloride	6170-42-9	99.45%
T0263	Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.
T12145L	N-Desethylsunitinib hydrochloride	1261432-05-6	99.42%
T12145L	N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibi...
T5475	ZD-4190	413599-62-9	99.42%
T5475	ZD-4190 is a compound that inhibits both the vascular endothelial growth factor receptor 2 (VEGFR2) and the epidermal growth factor receptor (EGFR) signaling pat...
T3476	JI-101	900573-88-8	99.41%
T3476	JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets vascular endothelial growth factor receptor type 2 (VEGFR-2), platelet derived growth factor rec...
T2054	Altiratinib	1345847-93-9	99.39%
T2054	Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, c...
T3S0153	Xanthatin	26791-73-1	99.39%
T3S0153	1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSC...
T2479	Tyrphostin A9	10537-47-0	99.36%
T2479	Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor
T6128	PHA-665752	477575-56-7	99.35%
T6128	PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.
T1837	BX-912	702674-56-4	99.34%
T1837	BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC...
T0129	Sanguinarine chloride	5578-73-4	99.33%
T0129	Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen specie...
T6057	URMC-099	1229582-33-5	99.32%
T6057	URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)...
T1754	ZM 306416	690206-97-4	99.31%
T1754	ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
T2514	Linifanib	796967-16-3	99.29%
T2514	Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDG...
T17219	Vatalanib free base	212141-54-3	99.27%
T17219	Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
T2576	Brivanib (alaninate)	649735-63-7	99.23%
T2576	Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activit...
T28077	MMPP	1895957-18-2	99.22%
T28077	MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pat...
T6351	MGCD-265 analog	875337-44-3	99.21%
T6351	MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 n...
T0093	Sorafenib tosylate	475207-59-1	99.2%
T0093	Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
T3463	NVP-ACC789	300842-64-2	99.19%
T3463	ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.
T12574	PTC299	1256565-36-2	99.19%
T12574	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA trans...