T9662 |
SRI 37892
|
1030769-75-5
|
98.92%
|
|
SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.
|
T4S2126 |
Ginkgetin
|
481-46-9
|
98.91%
|
|
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against...
|
T22775 |
Exo-IWR-1
|
1127442-87-8
|
98.85%
|
|
exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin s...
|
T5S1058 |
Triptonide
|
38647-11-9
|
98.8%
|
|
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-in...
|
TN7036 |
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
|
883715-23-9
|
98.66%
|
|
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem c...
|
T13004 |
SSTC3
|
1242422-09-8
|
98.65%
|
|
SSTC3 is a casein kinase 1α (CK1α) activator with a Kd of 32 nM.SSTC3 has potential antitumor activity, inhibits WNT signaling, and suppresses SHH medulloblastom...
|
T23602 |
ABC99
|
2331255-53-7
|
98.65%
|
|
ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the s...
|
T2237 |
ICG001
|
847591-62-2
|
98.63%
|
|
ICG001 (PRI-724 isomer) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with ...
|
T2310 |
CHIR-99021
|
252917-06-9
|
98.63%
|
|
CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021...
|
T21685 |
CCT 031374 hydrobromide
|
1219184-91-4
|
98.61%
|
|
CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.
|
T11284 |
FIDAS-3
|
1266684-01-8
|
98.59%
|
|
FIDAS-3 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-3 has anticancer activities. FIDAS-3 is a stilbene derivative and is a p...
|
T1716 |
Echinacoside
|
82854-37-3
|
98.58%
|
|
Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neu...
|
T2651 |
IWR-1
|
1127442-82-3
|
98.46%
|
|
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
|
T7333 |
Pyrvinium pamoate
|
3546-41-6
|
98.43%
|
|
Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug du...
|
T72437 |
PARP1/2/TNKS1/2-IN-1
|
2243453-32-7
|
98.40%
|
|
PARP1/2/TNKS1/2-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1 and TNKS2.PARP1/2/TNKS1/2-IN-1 has potential anti-tumor activity and induces apoptosis....
|
T77675 |
TNKS-2-IN-1
|
4765-59-7
|
98.4%
|
|
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity ag...
|
T4302 |
ICRT3
|
901751-47-1
|
98.32%
|
|
iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.
|
T13345 |
Wnt pathway activator 2
|
1360540-82-4
|
98.28%
|
|
Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.
|
T9151 |
Teplinovivint
|
1428064-91-8
|
98.27%
|
|
Teplinovivint is a potent wnt/β-catenin signaling pathway inhibitor. It has anti-inflammatory activity and has the potential for tendinopathy research.
|
T2003 |
ISX-9
|
832115-62-5
|
98.26%
|
|
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.
|