T2818 |
Methyl Vanillate
|
3943-74-6
|
100%
|
|
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariect...
|
T67866 |
YW2036
|
2131223-92-0
|
100%
|
|
YW2036 is an inhibitor of Wnt signaling pathway.
|
T77524 |
Carboxylesterase-IN-2
|
2764748-88-9
|
100%
|
|
Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.
|
T15363 |
FzM1.8
|
2204290-85-5
|
100%
|
|
FzM1.8 is an allosteric FZD4 agonist with a pEC50 of 6.4. FzM1.8 binds to FZD4, promotes TCF/LEF transcriptional activity in the absence of any WNT ligand, and a...
|
T8005 |
Cardiogenol C hydrochloride
|
1049741-55-0
|
100%
|
|
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
|
T19355 |
Heparan Sulfate
|
9050-30-0
|
|
|
Heparan Sulfate is a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on th...
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T2052 |
KY02111
|
1118807-13-8
|
|
|
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
|
T77692 |
F7H
|
897109-93-2
|
98%
|
|
F7H is a potent Frizzled receptor FZD7 antagonist with an IC50 value of 1.25 μM.F7H is a potent ligand for the transmembrane structural domain (TMD) of FZD7, wit...
|
T77719 |
TNIK-IN-7
|
1417795-24-4
|
98%
|
|
TNIK-IN-7 is a potent and selective Traf2 and Nck interacting kinase (TNIK) inhibitor (IC50: 11 nM) with antitumor activity for studying signaling and proliferat...
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T77733 |
TNKS-2-IN-2
|
2719726-91-5
|
98%
|
|
TNKS-2-IN-2 is a novel and potent TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breas...
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T38776 |
LP-922056
|
1365060-22-5
|
98%
|
|
LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
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TN4583 |
Moringin
|
73255-40-0
|
98%
|
|
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moring...
|
T4486 |
ICRT 14
|
677331-12-3
|
98%
|
|
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
|
T9557 |
TNIK-IN-2
|
2754265-76-2
|
98%
|
|
TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.
|
T9696 |
β-catenin-IN-2
|
1458664-10-2
|
98%
|
|
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
|
T6113 |
ICG-001
|
780757-88-2
|
98%
|
|
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related tr...
|
T3168 |
MN-64
|
92831-11-3
|
98%
|
|
MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
|
T27582 |
ICRT-5
|
18623-44-4
|
98%
|
|
iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity, blocking Wnt/β-catenin expression and inducing apoptosis. iCRT-5 can be u...
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T22884 |
JW 67
|
442644-28-2
|
98%
|
|
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including ...
|
T2161 |
Cardiogenol C
|
671225-39-1
|
98%
|
|
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
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