T62839 |
Dalzanemdor
|
1629853-48-0
|
98.20%
|
|
Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dys...
|
T12733 |
Rislenemdaz
|
808732-98-1
|
98.18%
|
|
Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).
|
T15623 |
JNJ-61432059
|
2035814-50-5
|
98.13%
|
|
JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8 (pIC50: 9.7 for GluA1...
|
T7579 |
1-BCP
|
34023-62-6
|
98%
|
|
1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.
|
T5522 |
NMDAR antagonist 1
|
2220162-06-9
|
98%
|
|
NMDAR antagonist 1 is an orally active, NR2B-selective NMDAR antagonist.
|
T6618 |
Orphenadrine Citrate
|
4682-36-4
|
98%
|
|
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
|
T7178 |
CNQX
|
115066-14-3
|
98%
|
|
CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)
|
T7580 |
CX546
|
215923-54-9
|
98%
|
|
CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.
|
T1909 |
L-701324
|
142326-59-8
|
98%
|
|
L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.
|
T0675 |
Topiramate
|
97240-79-4
|
98%
|
|
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associate...
|
T7591 |
Coluracetam
|
135463-81-9
|
98%
|
|
Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.
|
T7108 |
Omberacetam
|
157115-85-0
|
98%
|
|
Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to...
|
T15820 |
Mibampator
|
375345-95-2
|
97.63%
|
|
Mibampator (LY451395) is an effective and selective AMPA receptor potentiator.
|
T7355 |
IC87201
|
866927-10-8
|
97.44%
|
|
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
|
T10774 |
CFM-2
|
178616-26-7
|
97.16%
|
|
CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.
|
T16801 |
(RS)-(Tetrazol-5-yl)glycine
|
138199-51-6
|
95.00%
|
|
(RS)-(Tetrazol-5-yl)glycine (LY 285265) (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)gly...
|
T4171 |
PEAQX
|
459836-30-7
|
100%
|
|
PEAQX (NVP-AAM077)(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A...
|
T7706 |
LY-404187
|
211311-95-4
|
100%
|
|
LY404187 is a positive allosteric modulator of AMPA receptors
|
T10930 |
D-AP5
|
79055-68-8
|
100%
|
|
D-AP5 (D-APV) is a NMDA receptor antagonist.
|
T8435 |
YM90K
|
154164-30-4
|
100%
|
|
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
|