Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of the human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme, demonstrating IC50 values of 10 nM and 68 nM, respectively. It exhibits good metabolic stability [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 987.00 | |
50 mg | 10-14 weeks | $ 1,360.00 | |
100 mg | 10-14 weeks | $ 2,190.00 |
Description | (Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of the human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme, demonstrating IC50 values of 10 nM and 68 nM, respectively. It exhibits good metabolic stability [1]. |
Targets&IC50 | 11β-HSD1 (human):10 nM , 11β-HSD1 (mouse):68 nM |
In vivo | (Rac)-BMS-816336 (compound 6n) demonstrates high metabolic stability, as evidenced by its retention rates of 88%, 82%, and 72% in human, mouse, and rat models, respectively [1]. |
Molecular Weight | 341.44 |
Formula | C21H27NO3 |
CAS No. | T12663 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(Rac)-BMS-816336 T12663 Metabolism Dehydrogenase BMS 816336 BMS-816336 (Rac)BMS816336 (Rac) BMS 816336 BMS816336 inhibitor inhibit