Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
TN1298	6''-O-Acetylglycitin	134859-96-4	98%
TN1298	6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
T13100	TC HSD 21	330203-01-5	98%
T13100	TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).
T2637	ADH-1	229971-81-7	98%
T2637	Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
T13453	CGRP antagonist 1	1123757-49-2	98%
T13453	CGRP antagonist 1 is a highly potent antagonist of CGRP receptor(Ki and IC50 of 35 and 57 nM, respectively).
T11611	IDH1 Inhibitor 2	2244895-42-7	98%
T11611	IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
T10160	11β-HSD1-IN-1	1203956-47-1	98%
T10160	11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
T14780	BRD9185	2057420-29-6	98%
T14780	BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
T14383	AZD8329	1048668-70-7	98%
T14383	AZD8329 is a potent inhibitor of 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1)(IC50 of 9 nM for human 11β-HSD1), and displays excellent selectivity versus 1...
T12663	(Rac)-BMS-816336	T12663	98%
T12663	(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11...
T13054	T-3764518	1809151-56-1	98%
T13054	T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
T12614L	BMS-816336	1009583-20-3	98%
T12614L	BMS-816336 is a novel, orally bioavailable inhibitor, and potent against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM[1...
T27214	DSM421	2011769-21-2	98%
T27214	DSM421 is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown activity against ...
T67875	DHODH-IN-23	1346705-53-0	98%
T67875	DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.
T11238	Etamicastat	760173-05-5	98%
T11238	Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
T25209	CB29	315239-63-5	98%
T25209	CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
T11238L	Etamicastat hydrochloride	677773-32-9	98%
T11238L	Etamicastat hydrochloride is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
T15362	FX-11	213971-34-7	98%
T15362	FX-11 is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2)...
T67903	1-(biphenyl-4-ylsulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine	946394-50-9	98%
T67903	1-(biphenyl-4-ylsulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).
T11023	DHODH-IN-14	1364791-93-4	98%
T11023	DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726. DHODH-IN-14 is a dihydroorotate dehydrogenase (DHODH) inhibitor IC50 0.49 μM mouse liver DHODH. DHOD...
T38163	ML-148	451496-96-1	98%
T38163	ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydr...