T10160 |
11β-HSD1-IN-1
|
1203956-47-1
|
98%
|
|
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
|
T27214 |
DSM421
|
2011769-21-2
|
98%
|
|
DSM421 is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown activity against ...
|
T60240 |
ALDH1A3-IN-2
|
886502-08-5
|
98%
|
|
ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.
|
T25209 |
CB29
|
315239-63-5
|
98%
|
|
CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
|
T67903 |
1-(biphenyl-4-ylsulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine
|
946394-50-9
|
98%
|
|
1-(biphenyl-4-ylsulfonyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).
|
T67832 |
ALDH2 modulator 1
|
1629615-99-1
|
98%
|
|
ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
|
T25006 |
AGI-14100
|
1448346-43-7
|
98%
|
|
AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
|
T60364 |
DHODH-IN-17
|
16344-26-6
|
98%
|
|
DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM. DHODH-IN-17 is a 2- anilino nicotinic acid that can be used in the study of acute myeloid leukemi...
|
T73143 |
PHGDH-IN-3
|
2893778-31-7
|
98%
|
|
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 2.8 μM against PHGDH. PHGDH-IN-3 can be used in studies about can...
|
T3044 |
(E/Z)-Teriflunomide
|
108605-62-5
|
98%
|
|
Teriflunomide, a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.
|
T7732 |
Carbenoxolone
|
5697-56-3
|
98%
|
|
Carbenoxolone is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development ...
|
T2637 |
ADH-1
|
229971-81-7
|
98%
|
|
Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
|
T64360 |
HDHODH-IN-8
|
2757405-31-3
|
98%
|
|
hDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM. hDHODH-IN-8 has potent antiproliferative activity and exc...
|
T14780 |
BRD9185
|
2057420-29-6
|
98%
|
|
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
|
T16269 |
Nanaomycin A
|
52934-83-5
|
98%
|
|
Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells. Nanaomycin A is a selective inhibitor of DNMT3B (IC50 = 5...
|
T11611 |
IDH1 Inhibitor 2
|
2244895-42-7
|
98%
|
|
IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
|
T12663 |
(Rac)-BMS-816336
|
T12663
|
98%
|
|
(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzym...
|
T11238 |
Etamicastat
|
760173-05-5
|
98%
|
|
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
|
T14383 |
AZD8329
|
1048668-70-7
|
98%
|
|
AZD8329 is a selectable and potent inhibitor of human recombinant 11β-HSD1 and isolated human adipocyte 11ß-HSD1 and is an inhibitor of rat 11β-HSD1 (IC50 - 89nM...
|
T13054 |
T-3764518
|
1809151-56-1
|
98%
|
|
T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
|