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TargetMol | Compound Library

Anti-Neurodegenerative Disease Compound Library

Catalog No. L2620

Neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), spinal muscular atrophy (SMA), and amyotrophic lateral sclerosis (ALS), are incurable and debilitating conditions characterized by progressive degeneration of specific neurons within the brains of affected individuals. Neurodegenerative diseases have become an enormous economic burden that is projected to grow significantly over the next few decades in the absence of any new therapeutic interventions. Drugs for the central nervous system, including neurodegenerative diseases, that entered clinical development, have a considerably lower probability of reaching the marketplace (7%) than the industry average across other therapeutic areas (15%), and require a longer time for development and regulatory approval (average of 12.6 years) compared with most other diseases (e.g., 6.3 years for cardiovascular and 7.5 years for gastrointestinal indications). In this compound library, TargetMol collects 2154 compounds related to neurodegenerative diseases having therapeutic effect or acting on neurodegenerative disease-related targets.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2620

Anti-Neurodegenerative Disease Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS;
  • Targets include AchE, NMDA, CGRP, β -secretase, γ -secretase, Dopamine receptor, Adenosine receptor, 5-HT receptor, etc.;
  • Some of them are FDA-approved;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

5-HT Receptor
AChR
Dopamine Receptor
Adrenergic Receptor
GluR
GABA Receptor
Histamine Receptor
Autophagy
Opioid Receptor
Apoptosis
NMDAR
PDE
iGluR
COX
MAO
AChE
Beta Amyloid
Gamma-secretase
Monoamine Oxidase
Serotonin Transporter
Norepinephrine
Potassium Channel
GSK-3
Adenosine Receptor
PPAR
Sodium Channel
JNK
Calcium Channel
CaMK
LRRK2
Antibacterial
P450
HIV Protease
Caspase
CDK
Parasite
Bcr-Abl
Reactive Oxygen Species
Endogenous Metabolite
Src
Ferroptosis
BACE
Mitochondrial Metabolism
Phosphatase
Mitophagy
Beta-Secretase
Cannabinoid Receptor
Sigma receptor
Dehydrogenase
GlyT
Nrf2
FLT
Antibiotic
Imidazoline Receptor
Adenylyl cyclase
Transferase
Drug Metabolite
OX Receptor
P-gp
Influenza Virus
Phospholipase
c-Kit
Microtubule Associated
Antifungal
PI3K
LPL Receptor
P2Y Receptor
MRP
Wnt/beta-catenin
TRP/TRPV Channel
ERK
MT Receptor
AAK1 (AP2 associated kinase 1)
P2X Receptor
FAAH
Aurora Kinase
MEK
TNF
NO Synthase
S1P Receptor
Carbonic Anhydrase
Histone Methyltransferase
Virus Protease
Melatonin Receptor
ABC
PKA
VEGFR
PKC
ROS
BCL
JAK
CCR
IL Receptor
Interleukin
Akt
SARS-CoV
NF-κB
Neurokinin receptor
Chloride channel
Histone Demethylase
RAAS
Rho
Epoxide Hydrolase
Epigenetic Reader Domain
IGF-1R
EGFR
DNA/RNA Synthesis
Prostaglandin Receptor
Trk receptor
Sirtuin
Casein Kinase
IκB/IKK
c-Fms
FGFR
S6 Kinase
advanced glycation end products
NOS
ROR
Integrin
p38 MAPK
Estrogen/progestogen Receptor
c-Met/HGFR
Antioxidant
IFNAR
NADPH
Cysteine Protease
CSF-1R
Glucocorticoid Receptor
BTK
Guanylate cyclase
HSV
Lipoxygenase
TGF-beta/Smad
PGE Synthase
MAPK
Acyltransferase
STING
STAT
Retinoid Receptor
HDAC
CRISPR/Cas9
CGRP Receptor
Gap Junction Protein
Syk
NOD
HMG-CoA Reductase
Ras
HIF/HIF Prolyl-Hydroxylase
FAK
NOD-like Receptor (NLR)
HER
Proteasome
ATPase
Transaminase
NPC1L1
Monocarboxylate transporter
Amino Acids and Derivatives
Arrestin
Na+/Ca2+ Exchanger
GTPase
Progesterone Receptor
PARP
Hck
Liver X Receptor
FXR
ROCK
Aryl Hydrocarbon Receptor
Immunology/Inflammation related
Topoisomerase
Annexin A
E1/E2/E3 Enzyme
UGT
LDL
Raf
GRK
Glucosidase
Hexokinase
Monoamine Transporter
HCN Channel
Neuropeptide Y Receptor
PAK
PDGFR
DNA Alkylation
Stearoyl-CoA Desaturase (SCD)
Somatostatin
Chk
MMP
DUB
Androgen Receptor
SGLT
Antiviral
HSP
TLR
Free radical scavengers
Histone Acetyltransferase
Decarboxylase
GluCls
ALK
RSV
Neprilysin
GST
ATM/ATR
Reverse Transcriptase
GPR
AMPK
Hydroxylase
Adenosine deaminase
HIF
SGK
DNA Methyltransferase
IRAK
Thrombin
MLK

Keywords