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Home News Center

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News
14 Jun 2024

WIKIMOLE—3-Methyladenine

3-Methyladenine (Catalog No. T1879), also known as 3-MA, 3-Methyladenine, and NSC 66389, is a PI3K inhibitor that exerts its autophagy-inhibiting effects by inhibiting PI3K. It plays an important role in the study of cell signaling and autophagy processes.

WIKIMOLE—3-Methyladenine
Meeting
05 Jun 2024

Meet TargetMol at EACR 2024 Congress

Meet TargetMol at EACR 2024 Congress

Meet TargetMol at EACR 2024 Congress
Article
24 May 2024

WIKIMOLE—Osimertinib

Osimertinib is an orally available, third-generation EGFR inhibitor (EGFR-TKI) widely used for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations.

WIKIMOLE—Osimertinib
Article
26 Apr 2024

WIKIMOLE—Venetoclax

Venetoclax, Catalog number T2119, also known as GDC-0199, ABT 199, Venclexta, ABT-199, and ABT199. Venetoclax is a Bcl-2 inhibitor (Ki <0.01 nM) with high potency, selectivity, and oral activity. Venetoclax can induce autophagy and apoptosis.

WIKIMOLE—Venetoclax
Article
19 Apr 2024

WIKIMOLE—MG-132

MG-132, catalog number: T2154, also known as Z-LLL-al or Z-Leu-Leu-Leu-CHO, is a 26S proteasome inhibitor with an IC50 of 100 nM. It exhibits cell permeability and reversibility. MG-132 is capable of inducing apoptosis.

WIKIMOLE—MG-132
Advertisement
18 Apr 2024

Add 1 UDS/EURO to get a CCK-8 kit 1ml(100 tests)

Add 1 UDS/EURO to get a CCK-8 kit 1ml(100 tests)

Add 1 UDS/EURO to get a CCK-8 kit 1ml(100 tests)
Article
12 Apr 2024

WIKIMOLE—Gastrin I, human

Gastrin I, human, Catalog Number TP2030, also known as Gastrin I (human) or Gastrin 1, is an endogenous peptide produced in the stomach. It increases gastric pepsinogen and gastric acid secretion in rats through the CCK2 receptor.

WIKIMOLE—Gastrin I, human
Article
12 Apr 2024

WIKIMOLE—Olaparib

Gastrin I, human, Catalog Number TP2030, also known as Gastrin I (human) or Gastrin 1, is an endogenous peptide produced in the stomach. It increases gastric pepsinogen and gastric acid secretion in rats through the CCK2 receptor.

WIKIMOLE—Olaparib
Article
07 Apr 2024

WIKIMOLE—Y-27632 & Y-27632 2HCl

Y-27632, catalog number T1870, is a selective inhibitor of ROCK-I and ROCK-II, exhibiting oral bioavailability and ATP competitiveness. Y-27632 can also inhibit apoptosis of dissociation-induced mouse prostate stem cells or progenitor cells, commonly used in stem cell research and organoid culture.

WIKIMOLE—Y-27632 & Y-27632 2HCl
Article
20 Mar 2024

WIKIMOLE—A 83-01 & SB-431542 & SB 202190

A 83-01, catalog number T3031, also known as ALK5 Inhibitor IV, is an inhibitor of TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50 = 12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into induced pluripotent stem cells (iPSCs). It can also be used for organoid culture.

WIKIMOLE—A 83-01 & SB-431542 & SB 202190