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Gut Microbial Metabolite Library

Catalog No. L2540
  Library Compound List   Excel SDF

The gut microbiome in humans can be considered as an organ, which has functions critical for human metabolism, digestion, maintenance of gut barrier function and immunomodulation. Human metabolism is highly associated with altered microbiota composition.

Moreover, the gut microbiome has been linked to many diseases not classically associated with microbes, such as metabolic diseases including obesity and obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes mellitus (T2DM), rheumatoid arthritis and psychiatric disorders. The gastrointestinal (GI) tract is considered the largest immunological organ in the body having a central role in regulating immune homeostasis, relying on the dynamic interactions between intestinal epithelial cells, immune cells and microbiome in shaping specific immune responses to antigens. The gut microbiota contributes to host physiology through the production of a myriad of metabolites. These metabolites exert their effects within the host as signaling molecules (“messengers”) and substrates for metabolic reactions, such as influencing human energetics, suppressing inflammation through distinct mechanisms, regulating intestinal epithelial cell homeostasis, immune cell response, and neuronal excitability, etc. Therefore, the study on gut microbial metabolite will be helpful in discovering the mechanisms of some diseases and developing appropriate and effective therapies.

TargetMol’s Gut Microbial metabolite Library collects 351 gut microbial metabolites which can be used in research of gut microbiome and its related drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Features

  • A unique collection of 352 gut microbial metabolites which can be used for HTS and HCS;
  • Includes short chain fatty acids, amino acids, vitamins, saccharides, lipids, etc.;
  • Effective tool for research in gut microbiome metabolism and related drug development;
  • Detailed compound information with structure, target, IC50, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L2540)

Library Composition

Endogenous Metabolite (82)
Vitamin (12)
Amino Acids and Derivatives (5)
Antioxidant (5)
5-HT Receptor (4)
Antibacterial (4)
NMDAR (4)
AhR (3)
AChR (3)
Nucleoside Antimetabolite/Analog (3)
GPCR19 (2)
GluR (2)
GABA Receptor (2)
FXR (2)
Dehydrogenase (2)
PPAR (2)
TNF (2)
Antibiotic (2)
Transferase (1)
MT Receptor (1)
mTOR (1)
NF-κB (1)
Virus Protease (1)
Tyrosinase (1)
Trk receptor (1)
Potassium Channel (1)
PLK (1)
ROR (1)
Reductase (1)
P450 (1)
PARP (1)
Phosphorylase (1)
PKC (1)
Monocarboxylate transporter (1)
MPO (1)
iGluR (1)
MMP (1)
COX (1)
aconitase (1)
AMPK (1)
Apoptosis (1)
Arginase (1)
Autophagy (1)
CaMK (1)
Carbonic Anhydrase (1)
Caspase (1)
CFTR (1)
Chloride channel (1)
DHFR (1)
Mitochondrial Metabolism (1)
DNA/RNA Synthesis (1)
Dopamine Receptor (1)
Estrogen/progestogen Receptor (1)
Fatty Acid Synthase (1)
GlyT (1)
Histamine Receptor (1)
LDL (1)
Lipase (1)
MAO (1)
Melatonin Receptor (1)
Wnt/beta-catenin (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE