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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
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Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

Transcription Factor-Targeted Compound Library

Catalog No. L1380
  Library Compound List   Excel SDF

Transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of TFs is to regulate—turn on and off—genes in order to make sure that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. TFs function in a coordinated fashion to direct cell division, cell growth, and cell death throughout life; cell migration and organization (body plan) during embryonic development; and intermittently in response to signals from outside the cell, such as a hormone. There are up to 2600 TFs in the human genome.

TargetMol’s Transcription Factor-Targeted Compound Library collects 1200 compounds with unique structures targeting 13 different transcription factors with IC50 value below 2.5 μM, is a supplemental tool for research in cell division and cell cycle regulation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
Request Library
Get quote

Product Description

  • Quantity: well-chosen 1200 compounds with unique structures targeting transcription factor;
  • High bioactivity: All compounds with IC50 below 2.5 μM;
  • Targeting 13 transcription factors;
  • Detailed information: each compound has information about activity testing method, providing reference for your experimental design;
  • A powerful tool for cell division, cell cycle regulation, and transcription factor related study.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L1380)

Library Composition

NF-κB (223)
PPAR (113)
Apoptosis (112)
Autophagy (89)
STAT (83)
Androgen Receptor (62)
Endogenous Metabolite (45)
HIF/HIF Prolyl-Hydroxylase (39)
p53 (37)
COX (35)
Antibacterial (32)
HIF (29)
TNF (27)
ERK (26)
Aryl Hydrocarbon Receptor (23)
Ferroptosis (21)
Nrf2 (20)
Reactive Oxygen Species (20)
E1/E2/E3 Enzyme (20)
Mdm2 (19)
IL Receptor (17)
p38 MAPK (17)
c-Myc (16)
JNK (15)
DNA/RNA Synthesis (15)
JAK (14)
Akt (14)
HIV Protease (13)
c-Fms (13)
CSF-1R (12)
AhR (12)
BCL (12)
P450 (11)
MMP (10)
Caspase (10)
Antifungal (10)
Parasite (10)
Influenza Virus (9)
ROR (9)
Antibiotic (9)
AMPK (8)
IκB/IKK (8)
Sirtuin (8)
Lipoxygenase (8)
Dehydrogenase (7)
VEGFR (7)
HSP (7)
NO Synthase (7)
c-Kit (7)
Antioxidant (7)
Potassium Channel (6)
PARP (6)
CDK (6)
NOS (6)
Mitophagy (6)
Proteasome (5)
Interleukin (5)
Sodium Channel (5)
FLT (5)
Prostaglandin Receptor (5)
Tyrosinase (5)
Virus Protease (5)
TLR (5)
Wnt/beta-catenin (5)
Beta Amyloid (5)
Epigenetic Reader Domain (5)
PI3K (4)
PDE (4)
MEK (4)
Retinoid Receptor (4)
Drug Metabolite (4)
Anti-infection (4)
EGFR (4)
Topoisomerase (4)
Calcium Channel (4)
IAP (4)
TRP/TRPV Channel (4)
GABA Receptor (4)
GPR (4)
Glucocorticoid Receptor (4)
AChE (3)
AChR (3)
ROS (3)
Leukotriene Receptor (3)
NOD-like Receptor (NLR) (3)
Src (3)
Glucokinase (3)
RAR/RXR  (3)
TGF-beta/Smad (3)
transporter (3)
Mitochondrial Metabolism (3)
Progesterone Receptor (3)
IGF-1R (3)
PDGFR (3)
Cannabinoid Receptor (3)
PGE Synthase (3)
GSK-3 (3)
Estrogen/progestogen Receptor (3)
FAK (3)
Antifection (3)
Ras (2)
mTOR (2)
Decarboxylase (2)
Opioid Receptor (2)
NOD (2)
CaMK (2)
OCT (2)
Phosphatase (2)
P-gp (2)
DNA Alkylator/Crosslinker (2)
ATPase (2)
Raf (2)
Chloride channel (2)
SARS-CoV (2)
Integrin (2)
Glutathione Peroxidase (2)
Adrenergic Receptor (2)
HCV Protease (2)
HDAC (2)
HER (2)
Histone Acetyltransferase (2)
HSV (2)
IFNAR (2)
Estrogen Receptor/ERR (2)
S6 Kinase (2)
PKC (2)
STING (1)
ATP Citrate Lyase (1)
Reverse Transcriptase (1)
Adenosine deaminase (1)
UGT (1)
PKM (1)
PLK (1)
S1P Receptor (1)
Reductase (1)
Aminopeptidase (1)
RAAS (1)
Bcr-Abl (1)
Aromatase (1)
BACE (1)
Antiviral (1)
ATM/ATR (1)
Thrombin (1)
Proton pump (1)
PTEN (1)
Rho (1)
FLAP (1)
PKA (1)
Immunology/Inflammation related (1)
LTR (1)
Liver X Receptor (1)
LDL (1)
KLF (1)
DUB (1)
IRAK (1)
Epoxide Hydrolase (1)
Histamine Receptor (1)
MAPK (1)
Fatty Acid Synthase (1)
FGFR (1)
hCE (1)
HBV (1)
Guanylate cyclase (1)
GST (1)
gp120/CD4 (1)
Free radical scavengers (1)
MAO (1)
Dopamine Receptor (1)
PERK (1)
FOXO1 (1)
PDK (1)
PD-1/PD-L1 (1)
PAK (1)
cAMP (1)
CCR (1)
CFTR (1)
Nucleoside Antimetabolite/Analog (1)
NPC1L1 (1)
Microtubule Associated (1)
CXCR (1)
Norepinephrine (1)
Cysteine Protease (1)
NMDAR (1)
NAMPT (1)
NADPH-oxidase (1)
NADPH (1)
DNA Methyltransferase (1)
ABC (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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