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TargetMol | Compound Library

Natural Product Derivatives Library

Catalog No. NY1000

Historically, natural products have been pharma's treasure trove. According to the Natural Products Library Initiative at the Scripps Research Institute, "from 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (530/0) being either natural products or derived there from. “In a sense, this is not surprising. In nature, after all, creatures — and at the more basic level, structures, such as receptors and their ligands — have been co—evolving for billions of years.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. NY1000

Natural Product Derivatives Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • The library consists of more than 3745 members belonging 22 scaffolds (average 180 compounds per scaffold).
  • The library includes the following sub-libraries:
  • Cytisine-based sub-library
  • Matrine-based sub-library
  • Podophyllotoxin-based sub-library
  • Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc.
  • TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members).
  • NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc.).
  • More than 90% purity for each library member confirmed by LC-MS or NMR analysis.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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