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Human Endogenous Metabolite Library

Catalog No. L2500
  Library Compound List   Excel SDF

Changes in biological status (such as hypoxia, nutrients, drugs) usually cause the perturbations in the concentrations and fluxes of specific endogenous metabolites involved in a number of key disease-related or other specific cellular pathways. Extensive efforts in recent years have been focused on metabolic alterations in cancer, the products of intermediary metabolism has been a topic of considerable research interest. Cancer cells exhibit profound alterations in their metabolism. The quantitative measurement of the dynamic multiparametric metabolites, identification and quantification of intermediary metabolism can better help predict the tumor progress, understand the metabolic pathways and molecular mechanism of carcinogenesis. Current researches mainly focus on energy metabolism targeted compounds, such as nucleotides, amino acids, lipids, saccharide, etc. For example, alterations of cellular lipidomics (choline, phosphatidylcholine, cholesterol, etc.) reported in cancer provides a major opportunity to treat and prevent cancer; alterations of glucose metabolism (abnormal pyruvate, lactate, and isobutyric acid, etc.) in cancer cells, which also have become the hotspots in cancer research and therapeutics by targeting lipid metabolism and glucose metabolism.

TargetMol’s collection of 1400 endogenous metabolism-related compounds, Human Endogenous Metabolism Compound Library, can be used for research in endogenous metabolism-related diseases and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 1400 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening;
  • Effective tool for research in endogenous metabolism-related diseases, exploring the tumorigenesis, and drug discovery;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L2500)

Library Composition

Endogenous Metabolite (855)
Apoptosis (119)
Autophagy (83)
Antibacterial (81)
Reactive Oxygen Species (44)
NF-κB (44)
Antifungal (40)
Antibiotic (27)
COX (26)
Antioxidant (26)
DNA/RNA Synthesis (26)
P450 (22)
PPAR (20)
Influenza Virus (20)
HIV Protease (19)
Parasite (18)
Estrogen/progestogen Receptor (17)
Ferroptosis (17)
5-HT Receptor (16)
GABA Receptor (15)
ERK (14)
AChR (13)
Nucleoside Antimetabolite/Analog (12)
HSV (12)
TRP/TRPV Channel (12)
TNF (12)
Mitophagy (12)
Estrogen Receptor/ERR (12)
Caspase (11)
Amino Acids and Derivatives (11)
Histamine Receptor (10)
MMP (10)
Dehydrogenase (10)
Calcium Channel (10)
PI3K (10)
NO Synthase (10)
Dopamine Receptor (10)
Adrenergic Receptor (10)
Akt (9)
JNK (9)
Beta Amyloid (9)
iGluR (9)
Potassium Channel (9)
Prostaglandin Receptor (8)
Virus Protease (8)
AMPK (8)
Tyrosinase (8)
GluR (8)
p38 MAPK (8)
Lipoxygenase (8)
NMDAR (8)
Anti-infection (7)
ROS (7)
Glucocorticoid Receptor (6)
Phosphatase (6)
PKC (6)
Drug Metabolite (6)
Glucokinase (6)
IL Receptor (6)
Adenosine Receptor (6)
Sirtuin (5)
BCL (5)
Interleukin (5)
STAT (5)
Opioid Receptor (5)
Reductase (5)
Cannabinoid Receptor (5)
MAO (5)
AChE (5)
Mitochondrial Metabolism (5)
Progesterone Receptor (4)
Proteasome (4)
Chloride channel (4)
GPR (4)
PDE (4)
PARP (4)
PKA (4)
Aryl Hydrocarbon Receptor (4)
SARS-CoV (4)
HIF/HIF Prolyl-Hydroxylase (4)
ATPase (4)
Thyroid hormone receptor(THR) (4)
Norepinephrine (4)
Transferase (4)
Serotonin Transporter (4)
Topoisomerase (4)
NOS (4)
FXR (4)
Sodium Channel (4)
Antiviral (4)
LDL (3)
P-gp (3)
Arginase (3)
HMG-CoA Reductase (3)
Phospholipase (3)
Phosphorylase (3)
Microtubule Associated (3)
Xanthine Oxidase (3)
Monoamine Oxidase (3)
Platelet aggregation (3)
TLR (3)
CaMK (3)
AhR (3)
VEGFR (3)
TGF-beta/Smad (3)
GPCR19 (3)
EGFR (3)
RAAS (3)
MRP (2)
MT Receptor (2)
Neurokinin receptor (2)
UGT (2)
Acyltransferase (2)
NOD (2)
Wnt/beta-catenin (2)
mTOR (2)
Nrf2 (2)
Trk receptor (2)
Syk (2)
Serine/threonin kinase (2)
P2 Receptor (2)
ATP Citrate Lyase (2)
ROR (2)
p53 (2)
Aromatase (2)
ribosome (2)
Retinoid Receptor (2)
Androgen Receptor (2)
Antifection (2)
DNA Methyltransferase (2)
Bombesin Receptor (2)
Glutathione reductase (2)
HIF (2)
HER (2)
Melatonin Receptor (2)
HBV (2)
GST (2)
GSK-3 (2)
Glutathione Peroxidase (2)
CDK (2)
Gamma-secretase (2)
Free radical scavengers (2)
Fatty Acid Synthase (2)
FAAH (2)
DNA Alkylator/Crosslinker (2)
E1/E2/E3 Enzyme (2)
Histone Acetyltransferase (2)
HDAC (2)
Integrin (2)
Carbonic Anhydrase (2)
JAK (2)
MAPK (2)
MEK (2)
Lipid (1)
c-Myc (1)
CXCR (1)
FGFR (1)
SGLT (1)
Sigma receptor (1)
RSV (1)
DUB (1)
CYP19A1 (1)
Somatostatin (1)
Bradykinin Receptor (1)
stilbene oxidase (1)
Cysteine Protease (1)
Telomerase (1)
GlyT (1)
Thrombin (1)
LTR (1)
Fas/FasL (1)
NADPH (1)
DHFR (1)
Transaminase (1)
DNA (1)
transporter (1)
Epoxide Hydrolase (1)
aconitase (1)
Epigenetic Reader Domain (1)
DNA gyrase (1)
DYRK (1)
Lipase (1)
Rho (1)
GNRH Receptor (1)
IRAK (1)
Carboxypeptidase(CPG2) (1)
Immunology/Inflammation related (1)
ABC (1)
p97 (1)
PAFR (1)
PAK (1)
Casein Kinase (1)
IFNAR (1)
IAP (1)
PDK (1)
PGE Synthase (1)
CaSR (1)
HSP (1)
Oxytocin Receptor (1)
CFTR (1)
P2X Receptor (1)
IκB/IKK (1)
Antifolate (1)
Hexokinase (1)
PLK (1)
BACE (1)
Annexin A (1)
Hedgehog/Smoothened (1)
HCV Protease (1)
Proton pump (1)
PTEN (1)
Aminopeptidase (1)
Leukotriene Receptor (1)
NOD-like Receptor (NLR) (1)
Reverse Transcriptase (1)
cAMP (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE