Alkaloid Natural Product Library

Catalog No. L6110

Library Compound List Excel SDF

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, and mainly produced by plant. A large amount of research have found that alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma, anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. As research in alkaloids advances, alkaloids would play an important and visible role in modern drug development and provide a continuing source of novel drug leads.

TargetMol’s Alkaloid Natural Product Library carefully collects 468 alkaloids derived from plants, including Aconite, Periwinkle, Camptotheca acuminate, Belladonna, Coptis chinensis, etc. They have anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects. For example, vinca alkaloids obtained from Madagascar periwinkle plant are important for being cancer fighters and are the second-most-used class of cancer drugs and will stay among the original caner therapies. Lycorine, one of the main alkaloids of the Amaryllidaceae family, was found to be responsible for the pronounced antiviral and antibacterial activity of the crude extracts from the roots and leaves of Clivia miniata Regel. Tetrahydropalmatine, an isoquinoline alkaloid that is considered the active ingredient of Corydalis yanhusuo, has significant analgesic effects.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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Product Description

A unique collection of 468 natural alkaloids can be used for high throughput and high content screening；
Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects；
Detailed compound information with structure, target, and biological activity description；
NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Death & Disease. 2022, 13(11): 1-13. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..

10. Nature Communications. 2023, 14(1): 2756.. 11. Blood. 2021, 137(11): 1478-1490. 12. Nucleic Acids Research. 2021. 13. Nature Communications. 2023, 14(1): 7574. 14. Advanced Science. 2020, 7(16): 2000925. 15. Angewandte Chemie. 2021. 16. Acta Pharmaceutica Sinica B. 2022. 17. Protein & Cell. 2021, 12(11): 877-888. 18. Bone Research. 2023, 11(1): 54. 19. Pharmacology & Therapeutics. (2021): 107930. 20. Nature Communications. 2021, 12(1): 1-12. 21. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Autophagy (54)

Apoptosis (47)

Endogenous Metabolite (36)

AChR (34)

Antibacterial (33)

NF-κB (26)

Parasite (24)

AChE (22)

Antifungal (22)

Topoisomerase (20)

Antibiotic (20)

Adrenergic Receptor (14)

Microtubule Associated (13)

Potassium Channel (13)

5-HT Receptor (13)

Influenza Virus (13)

P450 (11)

Calcium Channel (11)

Sodium Channel (11)

p38 MAPK (9)

Dopamine Receptor (9)

DNA/RNA Synthesis (7)

Virus Protease (6)

ERK (6)

Indoleamine 2,3-Dioxygenase (IDO) (6)

BCL (6)

Antioxidant (6)

Anti-infection (6)

HIV Protease (5)

Antifection (5)

GABA Receptor (5)

PDE (5)

Adenosine Receptor (5)

Akt (5)

TNF (5)

Caspase (5)

PARP (4)

TRP/TRPV Channel (4)

Opioid Receptor (4)

P-gp (4)

Reactive Oxygen Species (4)

COX (4)

STAT (3)

Ferroptosis (3)

AMPK (3)

Histamine Receptor (3)

Platelet aggregation (3)

TLR (3)

TGF-beta/Smad (3)

IL Receptor (3)

EGFR (3)

Antiviral (3)

NOS (3)

Mitophagy (3)

MAO (3)

Nucleoside Antimetabolite/Analog (3)

JNK (3)

Aurora Kinase (2)

HSP (2)

MMP (2)

cAMP (2)

Prostaglandin Receptor (2)

FAAH (2)

HDAC (2)

Hedgehog/Smoothened (2)

Fatty Acid Synthase (2)

Serotonin Transporter (2)

NO Synthase (2)

Monoamine Oxidase (2)

HER (2)

Imidazoline Receptor (2)

FAK (2)

Dehydrogenase (2)

HIF/HIF Prolyl-Hydroxylase (2)

DYRK (2)

RAAS (2)

Smo (2)

SARS-CoV (2)

VEGFR (2)

Drug Metabolite (2)

ROS (2)

HIF (2)

E1/E2/E3 Enzyme (2)

Glucosidase (2)

PKC (2)

P2X Receptor (2)

Phospholipase (1)

GPR (1)

p53 (1)

GST (1)

IκB/IKK (1)

Beta Amyloid (1)

Hydroxylase (1)

Tyrosinase (1)

MEK (1)

Reverse Transcriptase (1)

FLT (1)

Proteasome (1)

Nrf2 (1)

c-Met/HGFR (1)

Tyrosine Kinases (1)

MRP (1)

PERK (1)

NADPH (1)

BACE (1)

LPL Receptor (1)

PI3K (1)

RANKL/RANK (1)

Arginase (1)

HCV Protease (1)

Hydrogenase (1)

CAT (1)

Proton pump (1)

Chloride channel (1)

ATPase (1)

Cysteine Protease (1)

Aryl Hydrocarbon Receptor (1)

MAPK (1)

HSV (1)

Beta-Secretase (1)

PGE Synthase (1)

mTOR (1)

DNA (1)

CaMK (1)

GluR (1)

PAK (1)

Immunology/Inflammation related (1)

PDGFR (1)

Monoamine Transporter (1)

Mitochondrial Metabolism (1)

DNA gyrase (1)

Bcr-Abl (1)

Adiponectin receptor (1)

iGluR (1)

S1P Receptor (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty